Barbour Group - Research

Our current research projects focus on:

1. Whole genome sequencing of oesophageal adenocarcinoma
   1. Intratumour heterogeneity
   2. Genomic evolution
   3. Circulating biomarkers for precision medicine
   4. Neoantigens and immune response
   5. Radiomics
2. Whole exome sequencing of melanoma
   1. Intratumour heterogeneity
   2. Circulating biomarkers for precision medicine
   3. Radiomics
3. Clinical Trials
   1. MASTERPLAN for pancreatic cancer

Student projects

• Use circulating tumour DNA (ctDNA) from stage III/IV melanoma patients to confirm the feasibility of using ‘liquid biopsy’ as a non-invasive test for assessing tumour burden. This will be used as a biomarker for prognostication and monitoring of treatment response.