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Dynamic tumour heterogeneity in melanoma therapy resources

    Summary table and guide for readings

    Please download this document and respond to the guiding questions as you read through the papers below

    Pre-reading

    Spoerri L, Beaumont KA, Anfosso A, Haass NK* (in press). Real-time cell cycle imaging in a 3D cell culture model of melanoma. Methods Mol Biol accepted for publication April 2nd 2016 

    Haass NK* (2015) Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?Melanoma Manag 2: 93-95, http://www.futuremedicine.com/doi/pdf/10.2217/mmt.15.1

    Beaumont KA, Hill DS, Daignault SM, Lui GY, Sharp DM, Gabrielli B, Weninger W, Haass NK* (2016) Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells. J Invest Dermatol 136: 1479-1489 

    Beaumont KA, Anfosso A, Ahmed F, Weninger W, Haass NK (2015). Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids. J Vis Exp 106: e53486

    Haass NK*, Beaumont KA, Hill DS, Anfosso A, Mrass P, Munoz MA, Kinjyo I, Weninger W (2014). Real-time cell cycle imaging during melanoma growth, invasion, and drug response. Pigment Cell Melanoma Res 27: 764-776  

    Beaumont KA, Mohana-Kumaran N, Haass NK* (2014; Epub 2013 Dec 23). Modeling Melanoma In Vitro and In Vivo.Special Issue "Melanoma and Neoplasms of Skin". Healthcare (Basel) 2: 27-46

    Extension papers

    Tonnessen CA, Haass NK* (2015) Melanoma: From tumor specific mutations to a new molecular taxonomy and innovative therapeutics.  In: Bieber T & Nestle F (Eds.): Personalized Treatment Options in Dermatology. Springer-Verlag Berlin Heidelberg, pp. 7-27, DOI: 10.1007/978-3-662-45840-2_2  (pdf link here)

    Haass NK, Sproesser K, Nguyen TK, Contractor R, Medina CA, Nathanson KL, Herlyn M, Smalley KS (2008). The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. Clin Cancer Res 14: 230-239

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