Our projects use a multidisciplinary approach, bringing together contemporary techniques in cancer biology, cellular and molecular biology, pharmacology, proteomics and immunology/immunotherapy. We use cutting edge models to: mimic disease, validate our discovers, elucidate mechanisms of action and tailor novel therapeutic approaches. Our research elucidates the cellular signaling and mechanism of regulation of innate lymphocites, and how manipulating these pathways would allow their maximum effectiveness to control different diseases.

Our current research projects aim to:

  • Use computational and system biology to identify new regulatory elements in cellular signalling of immune cells
  • Identify and understand novel immune checkpoints
  • Tailor immunotherapies to modulate immune responses in cancer and inflammatory diseases.

Student projects

We have research interests in, but are not restricted to:

  • Systems biology to identify new regulatory elements in cellular signalling of immune cells
  • Identifying and understanding novel immune checkpoints
  • Tailoring immunotherapies to modulate immune responses in cancer and inflammatory diseases
  • Development of novel pre-clinical models to mimic and study novel therapeutic targets for human disease