Honorary Professor John Upham
Affiliate Professor of Frazer Institute
Frazer Institute
Professor John Upham leads the Lung and allergy research group.
Book Chapters
Narla, Sai P. and Upham, John W. (2019). Immunity to rhinoviruses. Rhinovirus infections: rethinking the impact on human health and disease. (pp. 99-119) edited by Nathan Bartlett, Peter Wark and Darryl Knight. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-816417-4.00004-4
Upham, John W. and Yerkovich, Stephanie T. (2011). Interactions between allergens and dendritic cells: Pattern recognition receptors and their function in the pathogenesis of allergic respiratory diseases. Allergens and respiratory pollutants : the role of innate immunity. (pp. 245-275) edited by Marc A. Williams. Oxford, England: Biohealthcare Publishing. doi: 10.1016/B978-1-907568-54-1.50012-2
Rate, A. and Upham, J. (2008). The Epithelium and Immunoregulation. The Pulmonary Epithelium in Health and Disease. (pp. 201-214) edited by Proud, D.. UK: John Wiley & Sons Ltd. doi: 10.1002/9780470727010.ch11
Upham, John W., Stick, Stephen M. and Moodley, Yuben (2008). Lung cell biology. Pediatric respiratory medicine. (pp. 35-43) edited by Lynn M. Taussig and Louis I. Landau. Philadelphia, USA: Mosby/Elsevier. doi: 10.1016/B978-032304048-8.50008-6
Upham, J. W. and Hughes, T. (2006). Dendritic cells. Encyclopedia of Respiratory Medicine. (pp. 10-15) edited by Geoffrey J. Laurent and Steven D. Shapiro. Oxford: Elsevier Academic Press. doi: 10.1016/B0-12-370879-6/00111-3
Journal Articles
Thomas, Dennis, McDonald, Vanessa M., Stevens, Sean, Harvey, Erin S., Baraket, Melissa, Bardin, Philip, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Gillman, Andrew, Hew, Mark, Hodge, Sandra, James, Alan, Jenkins, Christine, Katelaris, Constance H., Katsoulotos, Gregory P., Langton, David, Lee, Joy, Marks, Guy, Peters, Matthew, Radhakrishna, Naghmeh, Reynolds, Paul N., Rimmer, Janet, Sivakumaran, Pathmanathan, Upham, John W., Wark, Peter, Yang, Ian A. and Gibson, Peter G. (2024). Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients. Allergy, 79 (2), 384-392. doi: 10.1111/all.15867
Vertigan, Anne E., Harvey, Erin S., Beyene, Tesfalidet, Van Buskirk, Joseph, Holliday, Elizabeth G., Bone, Sarah L., McDonald, Vanessa M., Horvat, Jay C., Murphy, Vanessa E., Jensen, Megan E., Morgan, Geoffrey G., Zosky, Graeme R., Peters, Matthew, Farah, Claude S., Jenkins, Christine R., Katelaris, Constance H., Harrington, John, Langton, David, Bardin, Philip, Katsoulotos, Gregory P., Upham, John W., Chien, Jimmy, Bowden, Jeffrey J., Rimmer, Janet, Bell, Rose and Gibson, Peter G. (2023). Impact of landscape fire smoke exposure on patients with asthma with or without laryngeal hypersensitivity. The Journal of Allergy and Clinical Immunology: In Practice, 11 (10), 3107-3115.e2. doi: 10.1016/j.jaip.2023.06.015
Malik, Bilal, Bartlett, Nathan W., Upham, John W., Nichol, Kristy S., Harrington, John and Wark, Peter A. B. (2023). Severe asthma
ILC2s
demonstrate enhanced proliferation that is modified by biologics. Respirology, 28 (8), 758-766. doi: 10.1111/resp.14506
Samaranayake, Chinthaka Bhagya, Upham, John, Tran, Khoa, Howard, Luke S, Nguyen, Sean, Lwin, Myo, Anderson, James, Wahi, Sudhir, Price, Laura C, Wort, Stephen, Li, Wei, McCabe, Colm and Keir, Gregory J (2023). Right ventricular functional recovery assessment with stress echocardiography and cardiopulmonary exercise testing after pulmonary embolism: a pilot prospective multicentre study. BMJ Open Respiratory Research, 10 (1) e001637, e001637. doi: 10.1136/bmjresp-2023-001637
Upham, John W. (2023). Can Allergen Immunotherapy Improve Antiviral Immunity in Patients with Allergic Asthma?. American Journal of Respiratory and Critical Care Medicine, 207 (9), 1112-1114. doi: 10.1164/rccm.202302-0234ed
Sikder, Md. Al Amin, Rashid, Ridwan B., Ahmed, Tufael, Sebina, Ismail, Howard, Daniel R., Ullah, Md. Ashik, Rahman, Muhammed Mahfuzur, Lynch, Jason P., Curren, Bodie, Werder, Rhiannon B., Simpson, Jennifer, Bissell, Alec, Morrison, Mark, Walpole, Carina, Radford, Kristen J., Kumar, Vinod, Woodruff, Trent M., Ying, Tan Hui, Ali, Ayesha, Kaiko, Gerard E., Upham, John W., Hoelzle, Robert D., Cuív, Páraic Ó., Holt, Patrick G., Dennis, Paul G. and Phipps, Simon (2023). Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection. Immunity, 56 (5), 1098-1114.e10. doi: 10.1016/j.immuni.2023.03.002
Anderson, Gary P., Irving, Louis B., Jarnicki, Andrew, Kedzierska, Katherine, Koutsakos, Marios, Kent, Stephen, Hurt, Aeron C., Wheatley, Adam K., Nguyen, Thi H. O., Snape, Natale and Upham, John W. (2023). Prime-boost, double-dose influenza vaccine immunity in COPD: a pilot observational study. ERJ Open Research, 9 (2) 00641-2021, 1-9. doi: 10.1183/23120541.00641-2021
Kritikos, Vicky, Harvey, Erin S., Stevens, Sean, Katelaris, Constance H., Langton, David, Rimmer, Janet, Farah, Claude S., Gillman, Andrew, Hew, Mark, Radhakrishna, Naghmeh, Thomas, Dennis, Gibson, Peter G., Baraket, Melissa, Bardin, Philip, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Grainge, Christopher, Harkness, Nicholas, Harrington, Zinta, Jenkins, Christine, Katsoulotos, Gregory P., McDonald, Vanessa M., Lee, Joy, Peters, Matthew, Reddel, Helen K., Reynolds, Paul N., Sivakumaran, Pathmanathan ... Wark, Peter A. B. (2023). Comorbidities modify the phenotype but not the treatment effectiveness to mepolizumab in severe eosinophilic asthma. Journal of Allergy and Clinical Immunology: In Practice, 11 (3), 885-895.e13. doi: 10.1016/j.jaip.2022.12.004
Valkenborghs, S.R., Wood, L.G., Callister, R., Upham, J.W., Grainge, C.L., Anderson, S., Williams, L.M., McLoughlin, R.F., Williams, E.J. and Scott, H.A. (2023). Excess visceral adipose tissue is associated with poorer lung function and increased airway inflammation in adults with asthma. Proceedings of the Nutrition Society, 82 (OCE2) E192. doi: 10.1017/s002966512300201x
Scott, Hayley A., Wood, Lisa G., Williams, Evan J., Weaver, Natasha and Upham, John W. (2022). Comparing the effect of acute moderate and vigorous exercise on inflammation in adults with asthma: a randomized controlled trial. Annals of the American Thoracic Society, 19 (11), 1848-1855. doi: 10.1513/AnnalsATS.202109-1053OC
McDiarmid, Katrina P., Wood, Lisa G., Upham, John W., MacDonald-Wicks, Lesley K., Shivappa, Nitin, Hebert, James R. and Scott, Hayley A. (2022). The impact of meal dietary inflammatory index on exercise-induced changes in airway inflammation in adults with asthma. Nutrients, 14 (20) 4392, 1-11. doi: 10.3390/nu14204392
Upham, John W. (2022). Home Administration of Biologics for Severe Asthma—A Good Option for Some but Not All. Journal of Allergy and Clinical Immunology: In Practice, 10 (9), 2324-2325. doi: 10.1016/j.jaip.2022.06.007
Samaranayake, Chinthaka B., Craigie, Michelle, Kempny, Aleksander, Bell, Peter T., McCann, Andrew, Wahi, Sudhir, Upham, John W., McCabe, Colm, Coucher, John and Keir, Gregory (2022). Right heart strain assessment on CTPA following acute pulmonary embolism: interobserver variability between expert radiologists and physicians. Respiratory Medicine, 200 106928, 1-7. doi: 10.1016/j.rmed.2022.106928
Hancock, Kerry L, Bosnic-Anticevich, Sinthia, Blakey, John D, Hew, Mark, Chung, Li Ping, Cvetkovski, Biljana, Claxton, Scott, Del Fante, Peter, Denton, Eve, Doan, Joe, Ranasinghe, Kanchanamala, Morgan, Lucy, Sharma, Anita, Smith, Peter K, Stewart, Deb, Thompson, Philip J, Wiseman, Russell, Upham, John W, Yan, Kwok Y, Carter, Victoria, Dhillon, Kiranjeet, Heraud, Florian, Le, Thao, Vella, Rebecca and Price, David (2022). Characterisation of the Australian adult population living with asthma: severe - exacerbation frequency, long-term OCS use and adverse effects. Pragmatic and Observational Research, Volume 13, 43-58. doi: 10.2147/por.s360044
Beyene, Tesfalidet, Harvey, Erin S., Van Buskirk, Joseph, McDonald, Vanessa M., Jensen, Megan E., Horvat, Jay C., Morgan, Geoffrey G., Zosky, Graeme R., Jegasothy, Edward, Hanigan, Ivan, Murphy, Vanessa E., Holliday, Elizabeth G., Vertigan, Anne E., Peters, Matthew, Farah, Claude S., Jenkins, Christine R., Katelaris, Constance H., Harrington, John, Langton, David, Bardin, Philip, Katsoulotos, Gregory P., Upham, John W., Chien, Jimmy, Bowden, Jeffrey J., Rimmer, Janet, Bell, Rose and Gibson, Peter G. (2022). ‘Breathing Fire’: impact of prolonged bushfire smoke exposure in people with severe asthma. International Journal of Environmental Research and Public Health, 19 (12) 7419, 1-15. doi: 10.3390/ijerph19127419
Cheng, Allen C., Dwyer, Dominic E., Holmes, Mark, Irving, Louis, Simpson, Graham, Senenayake, Sanjaya, Korman, Tony, Friedman, N Deborah, Cooley, Louise, Wark, Peter, Holwell, Anna, Bowler, Simon, Upham, John, Fatovich, Daniel M., Waterer, Grant, Blyth, Christopher C., Crawford, Nigel, Buttery, Jim, Marshall, Helen S., Clark, Julia E., Francis, Joshua, Macartney, Kristine, Kotsimbos, Tom and Kelly, Paul (2022). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2019: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence, 46. doi: 10.33321/cdi.2022.46.14
McCallum, Gabrielle B., Fong, Siew M., Grimwood, Keith, Nathan, Anna M., Byrnes, Catherine A., Ooi, Mong H., Nachiappan, Nachal, Saari, Noorazlina, Morris, Peter S., Yeo, Tsin W., Ware, Robert S., Elogius, Blueren W., Oguoma, Victor M., Yerkovich, Stephanie T., de Bruyne, Jessie, Lawrence, Katrina A., Lee, Bilawara, Upham, John W., Torzillo, Paul J. and Chang, Anne B. (2022). Extended versus standard antibiotic course duration in children <5 years of age hospitalized with community-acquired pneumonia in high-risk settings: four-week outcomes of a multicenter, double-blind, parallel, superiority randomized controlled trial. The Pediatric Infectious Disease Journal, Publish Ahead of Print (7), 549-555. doi: 10.1097/INF.0000000000003558
Begum, Husna, Dwyer, Dominic E., Holmes, Mark, Irving, Louis, Simpson, Graham, Senenayake, Sanjaya, Korman, Tony, Friedman, N Deborah, Cooley, Louise, Wark, Peter, Bowler, Simon, Kok, Jen, Upham, John, Fatovich, Daniel M., Waterer, Grant, Macartney, Kristine, Blyth, Christopher C., Crawford, Nigel, Buttery, Jim, Marshall, Helen S., Clark, Julia E., Francis, Joshua R., Kotsimbos, Tom, Kelly, Paul and Cheng, Allen (2022). Surveillance for severe influenza and COVID-19 in patients admitted to sentinel Australian hospitals in 2020: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence, 46. doi: 10.33321/cdi.2022.46.13
Carson‐Chahhoud, Kristin V., Thompson, Bruce R., Upham, John W. and Thoracic Society of Australia and New Zealand (2022). Philip Morris International buys inhaler company Vectura to expand reach in electronic cigarettes. Respirology, 27 (5), 328-330. doi: 10.1111/resp.14244
Upham, John W., Le Lievre, Chantal, Jackson, David J., Masoli, Matthew, Wechsler, Michael E. and Price, David B. (2022). Reply to “‘Nothing about us without us’ — What matters to patients with severe asthma?”. Journal of Allergy and Clinical Immunology: In Practice, 10 (3), 891-891. doi: 10.1016/j.jaip.2021.12.036
Samaranayake, Chinthaka B., Anderson, James, McCabe, Colm, Zahir, Syeda Farah, Upham, John and Keir, Gregory (2022). Direct oral anticoagulants for cancer associated venous thromboembolisms: a systematic review and network meta-analysis: DOACs for VTE in Cancer. Internal Medicine Journal, 52 (2) 15049, 272-281. doi: 10.1111/imj.15049
Snape, Natale, Anderson, Gary P., Irving, Louis B., Jarnicki, Andrew G., Hurt, Aeron C., Collins, Tina, Xi, Yang and Upham, John W. (2022). Vaccine strain affects seroconversion after influenza vaccination in COPD patients and healthy older people. npj Vaccines, 7 (1) 8, 8. doi: 10.1038/s41541-021-00422-4
Porsbjerg, Celeste M., Menzies-Gow, Andrew N., Tran, Trung N., Murray, Ruth B., Unni, Bindhu, Audrey Ang, Shi Ling, Alacqua, Marianna, Al-Ahmad, Mona, Al-Lehebi, Riyad, Altraja, Alan, Belevskiy, Andrey S., Björnsdóttir, Unnur S., Bourdin, Arnaud, Busby, John, Canonica, G. Walter, Christoff, George C., Cosio, Borja G., Costello, Richard W., FitzGerald, J. Mark, Fonseca, João A., Hansen, Susanne, Heaney, Liam G., Heffler, Enrico, Hew, Mark, Iwanaga, Takashi, Jackson, Daniel J., Kocks, Janwillem W.H., Kallieri, Maria, Bruce Ko, Hsin-Kuo ... van Boven, Job F.M. (2022). Global variability in administrative approval prescription criteria for biologic therapy in severe asthma. Journal of Allergy and Clinical Immunology: In Practice, 10 (5), 1202-1216.e23. doi: 10.1016/j.jaip.2021.12.027
Menzies-Gow, Andrew N., McBrien, Claire, Unni, Bindhu, Porsbjerg, Celeste M., Al-Ahmad, Mona, Ambrose, Christopher S., Dahl Assing, Karin, von Bülow, Anna, Busby, John, Cosio, Borja G., Fitzgerald, J. Mark, Garcia Gil, Esther, Hansen, Susanne, Aheaney, Liam G., Hew, Mark, Jackson, David J., Kallieri, Maria, Loukides, Stelios, Lugogo, Njira L., Papaioannou, Andriana I., Larenas-Linnemann, Désirée, Moore, Wendy C., Perez-De-llano, Luis A., Rasmussen, Linda M., Schmid, Johannes M., Siddiqui, Salman, Alacqua, Marianna, Tran, Trung N., Suppli Ulrik, Charlotte ... Price, David B. (2022). Real world biologic use and switch patterns in severe asthma: Data from the International Severe Asthma Registry and the US CHRONICLE Study. Journal of Asthma and Allergy, 15, 63-78. doi: 10.2147/JAA.S328653
Murray, Liisa M., Thillaiyampalam, Gayathri, Xi, Yang, Cristino, Alexandre S. and Upham, John W. (2021). Whole transcriptome analysis of high and low IFN‐α producers reveals differential response patterns following rhinovirus stimulation. Clinical and Translational Immunology, 10 (11) e1356, 1-17. doi: 10.1002/cti2.1356
Blakey, John, Chung, Li Ping, McDonald, Vanessa M., Ruane, Laurence, Gornall, John, Barton, Chris, Bosnic-Anticevich, Sinthia, Harrington, John, Hew, Mark, Holland, Anne E., Hopkins, Trudy, Jayaram, Lata, Reddel, Helen, Upham, John W., Gibson, Peter G. and Bardin, Philip (2021). Oral corticosteroids stewardship for asthma in adults and adolescents: A position paper from the Thoracic Society of Australia and New Zealand. Respirology, 26 (12), 1112-1130. doi: 10.1111/resp.14147
Upham, John W., Le Lievre, Chantal, Jackson, David J., Masoli, Matthew, Wechsler, Michael E., Price, David B., Mansur, Adel, Detoraki, Aikaterini, Altraja, Alan, James, Alan, Nanzer-Kelly, Alexandra, Côté, Andréanne, Menzies-Gow, Andrew, Papaioannou, Andriana, Cheffins, Anne-Maree, Bourdin, Arnaud, Mahboub, Bassam, Lipworth, Brian, Celis-Preciado, Carlos Andrés, Torres-Duque, Carlos, Bucca, Caterina, Porsbjerg, Celeste, Ulrik, Charlotte, Corrigan, Chris, Taube, Christian, Farah, Claude, Katelaris, Constance, Langton, David, Ryan, Dermot ... Harrington, Zinta (2021). Defining a severe asthma super-responder: findings from a Delphi Process. Journal of Allergy and Clinical Immunology: In Practice, 9 (11), 3997-4004. doi: 10.1016/j.jaip.2021.06.041
Samaranayake, Chinthaka B., Keir, Gregory, Slader, Simon A. A., Tseng, T., Tran, Khoa, Anderson, James, McCann, Andrew, McCabe, Colm and Upham, John W. (2021). Use of direct oral anticoagulants for acute pulmonary embolisms in obesity: a propensity matched multicenter case-control study. ERJ Open Research, 7 (3) 00379-2021, 00379-2021. doi: 10.1183/23120541.00379-2021
Thomas, Dennis, Harvey, Erin S., McDonald, Vanessa M., Stevens, Sean, Upham, John W., Katelaris, Constance H., Kritikos, Vicky, Gillman, Andrew, Harrington, John, Hew, Mark, Bardin, Philip, Peters, Matthew, Reynolds, Paul N., Langton, David, Baraket, Melissa, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Farah, Claude S., Grainge, Christopher, Jenkins, Christine, Katsoulotos, Gregory P., Lee, Joy, Radhakrishna, Naghmeh, Reddel, Helen K., Rimmer, Janet, Sivakumaran, Pathmanathan, Wark, Peter A.B. and Gibson, Peter G. (2021). Mepolizumab and oral corticosteroid stewardship: data from the Australian Mepolizumab Registry. Journal of Allergy and Clinical Immunology: In Practice, 9 (7), 2715-2724.e5. doi: 10.1016/j.jaip.2021.01.028
Shukla, Shakti D, Taylor, Steven L, Gibson, Peter G, Barker, Daniel, Upham, John W, Yang, Ian A, Reynolds, Paul N, Hodge, Sandra, James, Alan L, Rogers, Geraint B and Simpson, Jodie L (2021). Add-on azithromycin reduces sputum cytokines in non-eosinophilic asthma: An AMAZES substudy. Thorax, 76 (7), 733-736. doi: 10.1136/thoraxjnl-2020-216331
Niessen, Natalie M., Gibson, Peter G., Baines, Katherine J., Barker, Daniel, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Simpson, Jodie L. and Fricker, Michael (2021). Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment. Allergy, 76 (7) all.14768, 2090-2101. doi: 10.1111/all.14768
Ruffles, Tom J. C., Goyal, Vikas, Marchant, Julie M., Masters, I. Brent, Yerkovich, Stephanie, Buntain, Helen, Cook, Anne, Schultz, Andre, Upham, John W., Champion, Anita, Versteegh, Lesley and Chang, Anne B. (2021). Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial. The Lancet Respiratory Medicine, 9 (10), 1121-1129. doi: 10.1016/s2213-2600(21)00104-1
Ruffles, Tom J.C., Marchant, Julie M., Masters, Ian B., Yerkovich, Stephanie T., Wurzel, Danielle F., Gibson, Peter G., Busch, Greta, Baines, Katherine J., Simpson, Jodie L., Smith-Vaughan, Heidi C., Pizzutto, Susan J., Buntain, Helen M., Hodge, Gregory, Hodge, Sandra, Upham, John W. and Chang, Anne B. (2021). Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort study. Respirology, 26 (3), 241-248. doi: 10.1111/resp.13950
O Neill, Ciaran, Gibson, Peter G., Heaney, Liam G., Upham, John W., Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, Jenkins, Christine R., Peters, Matthew, Marks, Guy B., James, Alan L. and Simpson, Jodie L. (2021). The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma. European Respiratory Journal, 57 (2) 2002436. doi: 10.1183/13993003.02436-2020
Maltby, Steven, McDonald, Vanessa M., Upham, John W., Bowler, Simon D., Chung, Li Ping, Denton, Eve J., Fingleton, James, Garrett, Jeffrey, Grainge, Christopher L., Hew, Mark, James, Alan L., Jenkins, Christine, Katsoulotos, Gregory, King, Gregory G., Langton, David, Marks, Guy B., Menzies‐Gow, Andrew, Niven, Robert M., Peters, Matthew, Reddel, Helen K., Thien, Francis, Thomas, Paul S., Wark, Peter A. B., Yap, Elaine, Gibson, Peter G. and , (2021). Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings. Internal Medicine Journal, 51 (2) imj.14806, 169-180. doi: 10.1111/imj.14806
Samaranayake, Chinthaka B., Keir, Gregory, McCabe, Colm, Anderson, James, Tran, Khoa and Upham, John W. (2021). Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study. ERJ Open Research, 7 (1) 00762, 1-4. doi: 10.1183/23120541.00762-2020
van der Heide, Saskia L., Xi, Yang and Upham, John W. (2020). Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signaling. Frontiers in Cellular and Infection Microbiology, 10 510619, 1-12. doi: 10.3389/fcimb.2020.510619
Hew, Mark, McDonald, Vanessa M, Bardin, Phil G, Chung, Li Ping, Farah, Claude S, Barnard, Amanda, Cooper, Mark S, Gibson, Peter G and Upham, John W (2020). Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia. Medical Journal of Australia, 213 (7), 316-320. doi: 10.5694/mja2.50758
Xi, Yang and Upham, John W. (2020). Plasmacytoid dendritic cells and asthma: a review of current knowledge. Expert Review of Respiratory Medicine, 14 (11), 1095-`1106. doi: 10.1080/17476348.2020.1803741
Loh, Zhixuan, Simpson, Jennifer, Ullah, Ashik, Zhang, Vivian, Gan, Wan J., Lynch, Jason P., Werder, Rhiannon B., Sikder, Al Amin, Lane, Katie, Sim, Choon Boon, Porrello, Enzo, Mazzone, Stuart B., Sly, Peter D., Steptoe, Raymond J., Spann, Kirsten M., Sukkar, Maria B., Upham, John W. and Phipps, Simon (2020). HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling. PLoS Pathogens, 16 (7) e1008651, 1-21. doi: 10.1371/journal.ppat.1008651
Upham, John W. and Jurak, Lisa M. (2020). How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?. Clinical and Experimental Allergy, 50 (9) cea.13694, 994-1006. doi: 10.1111/cea.13694
Murray, Liisa M., Yerkovich, Stephanie T., Ferreira, Manuel A. and Upham, John W. (2020). Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsets. European Respiratory Journal, 56 (4) 1902453. doi: 10.1183/13993003.02453-2019
Simpson, Jennifer, Loh, Zhixuan, Ullah, Md Ashik, Lynch, Jason P., Werder, Rhiannon B., Collinson, Natasha, Zhang, Vivian, Dondelinger, Yves, Bertrand, Mathieu J M, Everard, Mark L., Blyth, Christopher C., Hartel, Gunter, Van Oosterhout, Antoon J., Gough, Peter J., Bertin, John, Upham, John W., Spann, Kirsten M. and Phipps, Simon (2020). Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells. American Journal of Respiratory and Critical Care Medicine, 201 (11), 1358-1371. doi: 10.1164/rccm.201906-1149OC
Hodge, Sandra, Macowan, Matthew, Liu, Hong, Hamon, Rhys, Chen, Alice C.-H., Marchant, Julie M., Pizzutto, Susan J., Upham, John W. and Chang, Anne B. (2020). Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in children. Pediatric Pulmonology, 55 (6), 1414-1423. doi: 10.1002/ppul.24728
Harvey, Erin S., Langton, David, Katelaris, Constance, Stevens, Sean, Farah, Claude S., Gillman, Andrew, Harrington, John, Hew, Mark, Kritikos, Vicky, Radhakrishna, Naghmeh, Bardin, Philip, Peters, Matthew, Reynolds, Paul N., Upham, John W., Baraket, Melissa, Bowler, Simon, Bowden, Jeffrey, Chien, Jimmy, Chung, Li Ping, Grainge, Christopher, Jenkins, Christine, Katsoulotos, Gregory P., Lee, Joy, McDonald, Vanessa M., Reddel, Helen K., Rimmer, Janet, Wark, Peter A B and Gibson, Peter G. (2020). Mepolizumab effectiveness and identification of super-responders in severe asthma. The European Respiratory Journal, 55 (5) 1902420, 1902420. doi: 10.1183/13993003.02420-2019
Turner, Steve and Upham, John W. (2020). Asthma in children and adults – what are the differences and what can they tell us about asthma?. Frontiers in Pediatrics, 8 141, 141. doi: 10.3389/fped.2020.00141
Maltby, Steven, Gibson, Peter G., Reddel, Helen K., Smith, Lorraine, Wark, Peter A. B., King, Gregory G., Upham, John W., Clark, Vanessa L., Hew, Mark, Owens, Louisa, Oo, Stephen, James, Alan L., Thompson, Bruce, Marks, Guy B. and McDonald, Vanessa M. (2020). Severe Asthma Toolkit: An online resource for multidisciplinary health professionals - Needs assessment, development process and user analytics with survey feedback. BMJ Open, 10 (3) e032877, 1-10. doi: 10.1136/bmjopen-2019-032877
Lynch, Jason P., Werder, Rhiannon B., Curren, Bodie F., Sikder, Md. Al Amin, Ullah, Ashik, Sebina, Ismail, Rashid, Ridwan B., Zhang, Vivian, Upham, John W., Hill, Geoff R., Steptoe, Raymond J. and Phipps, Simon (2020). Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma. Mucosal Immunology, 13 (4), 652-664. doi: 10.1038/s41385-020-0268-8
Kailaivasan, Thina H, Timbrell, Victoria L, Solley, Graham, Smith, William B, McLean-Tooke, Andrew, van Nunen, Sheryl, Smith, Peter, Upham, John W, Langguth, Daman and Davies, Janet M (2020). Biogeographical variation in specific IgE recognition of temperate and subtropical grass pollen allergens in allergic rhinitis patients : Regional IgE specificity for grass pollens. Clinical and Translational Immunology, 9 (2) e01103, e01103. doi: 10.1002/cti2.1103
Blyth, Christopher C., Cheng, Allen C., Crawford, Nigel W., Clark, Julia E., Buttery, Jim P., Marshall, Helen S., Francis, Joshua R., McRae, Jocelynne, Kotsimbos, Tom, Kelly, Paul M., Macartney, Kristine K., on behalf of the Paediatric Active Enhanced Disease Surveillance (PAEDS), Influenza Complications Alert Network (FluCAN) Collaboration and Upham, John (2020). The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018. Vaccine, 38 (13), 2779-2787. doi: 10.1016/j.vaccine.2020.02.031
Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Senanayake, Sanjaya, Cooley, Louise, Irving, Louis B., Simpson, Graham, Korman, Tony, Macartney, Kristine, Friedman, N. Deborah, Wark, Peter, Howell, Anna, Blyth, Christopher C., Crawford, Nigel, Buttery, Jim, Bowler, Simon, Upham, John W., Waterer, Grant W., Kotsimbos, Tom and Kelly, Paul M. (2019). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence Quarterly Report, 43. doi: 10.33321/cdi.2019.43.48
Chung, Li Ping, Upham, John W., Bardin, Philip G. and Hew, Mark (2019). Rational oral corticosteroid use in adult severe asthma: a narrative review. Respirology, 25 (2) resp.13730, 161-172. doi: 10.1111/resp.13730
Cesana-Nigro, Nicole, Keshvari, Sahar, Barclay, Johanna L., Sorbello, Jane, Upham, John W., Benham, Helen, Anderson, Stephen T., Steiger, Natasha, Prins, Johannes B. and Inder, Warrick J. (2019). The effect of glucocorticoids on Thrombospondin-1, Osteocalcin and the Thrombospondin-1:Osteocalcin ratio in humans. Clinical Endocrinology, 91 (6) cen.14108, 728-736. doi: 10.1111/cen.14108
Kerstjens, Huib A. M., Upham, John W. and Yang, Ian A. (2019). Airway pharmacology: treatment options and algorithms to treat patients with chronic obstructive pulmonary disease. Journal of Thoracic Disease, 11 (S17), S2200-S2209. doi: 10.21037/jtd.2019.10.57
Gibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather and Simpson, Jodie L. (2019). Efficacy of azithromycin in severe asthma from the AMAZES randomised trial. ERJ Open Research, 5 (4) 00056-2019, 00056-2019. doi: 10.1183/23120541.00056-2019
Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Senanayake, Sanjaya, Cooley, Louise, Irving, Louis B., Simpson, Graham, Korman, Tony, Macartney, Kristine, Friedman, N Deborah, Wark, Peter, Howell, Anna, Blyth, Christopher C., Bowler, Simon, Upham, John, Waterer, Grant W., Kotsimbos, Tom and Kelly, Paul M. (2019). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2017: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence, 43. doi: 10.33321/cdi.2019.43.39
Taylor, Steven L., Leong, Lex E. X., Mobegi, Fredrick M., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B., Gibson, Peter G., Rogers, Geraint B. and Simpson, Jodie L. (2019). Long-term azithromycin reduces Haemophilus influenzae and increases antibiotic resistance in severe asthma. American Journal of Respiratory and Critical Care Medicine, 200 (3), 309-317. doi: 10.1164/rccm.201809-1739OC
Revez, Joana A., Bain, Lisa M., Watson, Rick M., Towers, Michelle, Collins, Tina, Killian, Kieran J., O'Byrne, Paul M., Gauvreau, Gail M., Upham, John W. and Ferreira, Manuel A. R. (2019). Effects of interleukin‐6 receptor blockade on allergen‐induced airway responses in mild asthmatics. Clinical & Translational Immunology, 8 (6) e1044, e1044. doi: 10.1002/cti2.1044
Chang, Anne B., Fong, Siew Moy, Yeo, Tsin Wen, Ware, Robert S., McCallum, Gabrielle B., Nathan, Anna M., Ooi, Mong H., de Bruyne, Jessie, Byrnes, Catherine A., Lee, Bilawara, Nachiappan, Nachal, Saari, Noorazlina, Torzillo, Paul, Smith-Vaughan, Heidi, Morris, Peter S., Upham, John W. and Grimwood, Keith (2019). HOspitalised Pneumonia Extended (HOPE) Study to reduce the long-term effects of childhood pneumonia: protocol for a multicentre, double-blind, parallel, superiority randomised controlled trial. BMJ Open, 9 (4) e026411, e026411. doi: 10.1136/bmjopen-2018-026411
McDonald, Vanessa M., Fingleton, James, Agusti, Alvar, Hiles, Sarah A., Clark, Vanessa L., Holland, Anne E., Marks, Guy B., Bardin, Philip P., Beasley, Richard, Pavord, Ian D., Wark, Peter A.B., Gibson, Peter G., Treatable Traits Down Under International Workshop, Agusti, Alvar, Anderson, Gary, Bardin, Philip P., Beasley, Richard, Cheng, Allen, Chung, Li Ping, Clark, Vanessa L., Dabscheck, Eli, Dharmage, Shyamali, Fingleton, James, Gibson, Peter, Hardy, Jo, Hew, Mark, Hiles, Sarah A., Holland, Anne E., James, Alan ... Wark, Peter A.B. (2019). Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report. European Respiratory Journal, 53 (5) 1802058. doi: 10.1183/13993003.02058-2018
Upham, John W. (2019). Contemporary Concise Review 2018: asthma and chronic obstructive pulmonary disease: asthma and COPD. Respirology, 24 (7) resp.13553, 693-699. doi: 10.1111/resp.13553
Marsh, Robyn L., Smith-Vaughan, Heidi C., Chen, Alice C.H., Marchant, Julie M., Yerkovich, Stephanie T., Gibson, Peter G., Pizzutto, Susan J., Hodge, Sandra, Upham, John W. and Chang, Anne B. (2019). Multiple respiratory microbiota profiles are associated with lower airway inflammation in children with protracted bacterial bronchitis. Chest, 155 (4), 778-786. doi: 10.1016/j.chest.2019.01.002
Fricker, Michael, Gibson, Peter G., Powell, Heather, Simpson, Jodie L., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa and Baines, Katherine J. (2019). A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma. Journal of Allergy and Clinical Immunology, 144 (1), 51-60.e11. doi: 10.1016/j.jaci.2018.12.1020
McDonald, Vanessa M., Hiles, Sarah A., Godbout, Krystelle, Harvey, Erin S., Marks, Guy B., Hew, Mark, Peters, Matthew, Bardin, Philip G., Reynolds, Paul N., Upham, John W., Baraket, Melissa, Bhikoo, Zaheerodin, Bowden, Jeffrey, Brockway, Ben, Chung, Li Ping, Cochrane, Belinda, Foxley, Gloria, Garrett, Jeffrey, Jayaram, Lata, Jenkins, Christine, Katelaris, Constance, Katsoulotos, Gregory, Koh, Mariko S., Kritikos, Vicky, Lambert, Marina, Langton, David, Lara Rivero, Alexis, Middleton, Peter G., Nanguzgambo, Aldoph ... Gibson, Peter G. (2019). Treatable traits can be identified in a severe asthma registry and predict future exacerbations. Respirology, 24 (1), 37-47. doi: 10.1111/resp.13389
Murray, Liisa, Xi, Yang and Upham, John W. (2019). CLEC4C gene expression can be used to quantify circulating plasmacytoid dendritic cells. Journal of Immunological Methods, 464, 126-130. doi: 10.1016/j.jim.2018.11.001
Chung, Li Ping, Hew, Mark, Bardin, Philip, McDonald, Vanessa M. and Upham, John W. (2018). Managing patients with severe asthma in Australia: current challenges with the existing models of care. Internal Medicine Journal, 48 (12), 1536-1541. doi: 10.1111/imj.14103
Menzies-Gow, Andrew, Canonica, G-Walter, Winders, Tonya A., Correia de Sousa, Jaime, Upham, John W. and Fink-Wagner, Antje-Henriette (2018). A charter to improve patient care in severe asthma. Advances in Therapy, 35 (10), 1485-1496. doi: 10.1007/s12325-018-0777-y
Blyth, Christopher C., Macartney, Kristine K., McRae, Jocelynne, Clark, Julia E., Marshall, Helen S., Buttery, Jim, Francis, Joshua R., Kotsimbos, Tom, Kelly, Paul M., Cheng, Allen C., on behalf of the Paediatric Active Enhanced Disease Surveillance (PAEDS), Influenza Complications Alert Network (FluCAN) Collaboration, Elliott, Elizabeth, McIntyre, Peter, Booy, Robert, Wood, Nicholas, Britton, Phillip, Kesson, Alison, Richmond, Peter, Snelling, Tom, Crawford, Nigel, Gold, Mike, Kynasto, Anne, Holmes, Mark, Dwyer, Dominic E., Senenayake, Sanjaya, Cooley, Louise, Irving, Louis, Simpson, Graham ... Waterer, Grant (2018). Influenza Epidemiology, Vaccine Coverage and Vaccine Effectiveness in Children Admitted to Sentinel Australian Hospitals in 2017: Results from the PAEDS-FluCAN Collaboration. Clinical Infectious Diseases, 68 (6), 940-948. doi: 10.1093/cid/ciy597
Jurak, Lisa M., Xi, Yang, Landgraf, Megan, Carroll, Melanie L., Murray, Liisa and Upham, John W. (2018). Interleukin 33 selectively augments rhinovirus-induced type 2 immune responses in asthmatic but not healthy people. Frontiers in Immunology, 9 (AUG) 1895, 1895. doi: 10.3389/fimmu.2018.01895
Upham, John W. (2018). The bronchial epithelial IgE secretory IgA system in asthma. American Journal of Respiratory and Critical Care Medicine, 198 (9) rccm.201806-1042LE, 1236-1236. doi: 10.1164/rccm.201806-1042LE
Upham, John W. and Chung, Li Ping (2018). Optimising treatment for severe asthma. Medical Journal of Australia, 209 (2 Suppl), S22-S27. doi: 10.5694/mja18.00175
Revez, J. A., Killian, K. J., O'Byrne, P. M., Boulet, L-P., Upham, J. W., Gauvreau, G. M. and Ferreira, M. A. R. (2018). Sputum cytology during late-phase responses to inhalation challenge with different allergens. Allergy, 73 (7), 1470-1478. doi: 10.1111/all.13415
Werder, Rhiannon B., Lynch, Jason P., Simpson, Jennifer C., Zhang, Vivian, Hodge, Nick H., Poh, Matthew, Forbes-Blom, Elizabeth, Kulis, Christina, Smythe, Mark L., Upham, John W., Spann, Kirsten, Everard, Mark L. and Phipps, Simon (2018). PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production. Science Translational Medicine, 10 (440) eaao0052, eaao0052. doi: 10.1126/scitranslmed.aao0052
Chen, Alice C. -H., Pena, Olga M., Nel, Hendrik J., Yerkovich, Stephanie T., Chang, Anne B., Baines, Katherine J., Gibson, Peter G., Petsky, Helen L., Pizzutto, Susan J., Hodge, Sandra, Masters, Ian B., Buntain, Helen L. and Upham, John W. (2018). Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles. Pediatric Pulmonology, 53 (5), 575-582. doi: 10.1002/ppul.23984
Werder, Rhiannon B, Zhang, Vivian, Lynch, Jason P, Snape, Natale, Upham, John W, Spann, Kirsten and Phipps, Simon (2018). Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity. The Journal of allergy and clinical immunology, 141 (5), 1607-1619.e9. doi: 10.1016/j.jaci.2017.07.051
Hiles, S. A., Harvey, E. S., McDonald, V. M., Peters, M., Bardin, P., Reynolds, P. N., Upham, J. W., Baraket, M., Bhikoo, Z., Bowden, J., Brockway, B., Chung, L. P., Cochrane, B., Foxley, G., Garrett, J., Hew, M., Jayaram, L., Jenkins, C., Katelaris, C., Katsoulotos, G., Koh, M. S., Kritikos, V., Lambert, M., Langton, D., Rivero, A. L., Marks, G. B., Middleton, P. G., Nanguzgambo, A., Radhakrishna, N. ... Gibson, P. G. (2018). Working while unwell: Workplace impairment in people with severe asthma. Clinical and Experimental Allergy, 48 (6), 650-662. doi: 10.1111/cea.13153
Chen, Alice C. -H., Tran, Hai B., Xi, Yang, Yerkovich, Stephanie T., Baines, Katherine J., Pizzutto, Susan J., Carroll, Melanie, Robertson, Avril A. B., Cooper, Matthew A., Schroder, Kate, Simpson, Jodie L., Gibson, Peter G., Hodge, Greg, Masters, Ian B., Buntain, Helen M., Petsky, Helen L., Prime, Samantha J., Chang, Anne B., Hodge, Sandra and Upham, John W. (2018). Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis. ERJ Open Research, 4 (1) 00130-2017, 00130-2017. doi: 10.1183/23120541.00130-2017
Lynch, Jason P., Werder, Rhiannon B., Loh, Zhixuan, Sikder, Md Al Amin, Curren, Bodie, Zhang, Vivian, Rogers, Matthew J. , Lane, Katie, Simpson, Jennifer, Mazzone, Stuart B., Spann, Kirsten, Hayball, John, Diener, Kerrilyn, Everard, Mark L., Blyth, Christopher C., Forstner, Christian, Dennis, Paul G., Murtaza, Nida, Morrison, Mark, Ó Cuív, Páraic, Zhang, Ping, Haque, Ashraful, Hill, Geoffrey R., Sly, Peter D., Upham, John W. and Phipps, Simon (2017). Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. The Journal of Experimental Medicine, 215 (2), 537-557. doi: 10.1084/jem.20170298
Xi, Yang, Troy, Niamh M., Anderson, Denise, Pena, Olga M., Lynch, Jason P., Phipps, Simon, Bosco, Anthony and Upham, John W. (2017). Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16. Frontiers in Immunology, 8 (OCT) 1351, 1351. doi: 10.3389/fimmu.2017.01351
Teoh, Laurel, Mackay, Ian M, Van Asperen, Peter P, Acworth, Jason P, Hurwitz, Mark, Upham, John W, Siew, Weng Hou, Wang, Claire Y T, Sloots, Theo P, Neeman, Teresa and Chang, Anne B (2017). Presence of atopy increases the risk of asthma relapse. Archives of disease in childhood, 103 (4), 346-351. doi: 10.1136/archdischild-2017-312982
Chen, Alice C.-H., Xi, Yang, Carroll, Melanie, Petsky, Helen L., Gardiner, Samantha J., Pizzutto, Susan J., Yerkovich, Stephanie T., Baines, Katherine J., Gibson, Peter G., Hodge, Sandra, Masters, Ian B., Buntain, Helen M., Chang, Anne B. and Upham, John W. (2017). Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β. ERJ Open Research, 3 (4) 00025-2017, 00025-2017. doi: 10.1183/23120541.00025-2017
Gupta, D., Winckel, K., Burrows, J., Ross, J. and Upham, J. W. (2017). Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trial. Journal of Smoking Cessation, 12 (1), 1-10. doi: 10.1017/jsc.2015.14
Gibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather, Taylor, Steven L., Leong, Lex E. X., Rogers, Geraint B. and Simpson, Jodie L. (2017). Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. The Lancet, 390 (10095), 659-668. doi: 10.1016/S0140-6736(17)31281-3
Hukins, Craig, Wong, Mimi, Murphy, Michelle and Upham, John (2017). Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit. Internal Medicine Journal, 47 (7), 784-792. doi: 10.1111/imj.13403
Pizzutto, Susan J., Hare, Kim M. and Upham, John W. (2017). Bronchiectasis in children: current concepts in immunology and microbiology. Frontiers in Pediatrics, 5 123, 123. doi: 10.3389/fped.2017.00123
Taylor, Steven L., Leong, Lex E. X., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B., Gibson, Peter G., Simpson, Jodie L. and Rogers, Geraint B. (2017). Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology. Journal of Allergy and Clinical Immunology, 141 (1), 94-103.e15. doi: 10.1016/j.jaci.2017.03.044
Wurzel, Danielle F., Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W. and Chang, Anne B. (2017). Response. Chest, 151 (4), 940-941. doi: 10.1016/j.chest.2016.12.030
Fricker, Michael, Heaney, Liam G. and Upham, John W. (2017). Can biomarkers help us hit targets in difficult-to-treat asthma?. Respirology, 22 (3), 430-442. doi: 10.1111/resp.13014
Upham, John W. and Xi, Yang (2017). Dendritic cells in human lung disease: recent advances. Chest, 151 (3), 668-673. doi: 10.1016/j.chest.2016.09.030
Arikkatt, Jaisy, Ullah, Md Ashik, Short, Kirsty Renfree, Zhang, Vivian, Gan, Wan Jun, Loh, Zhixuan, Werder, Rhiannon B., Simpson, Jennifer, Sly, Peter D., Mazzone, Stuart B., Spann, Kirsten M., Ferreira, Manuel A R., Upham, John W., Sukkar, Maria B. and Phipps, Simon (2017). RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma. eLife, 6 e21199. doi: 10.7554/eLife.21199
Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Irving, Louis B., Korman, Tony M., Senenayake, Sanjaya, Macartney, Kristine K., Blyth, Christopher C., Brown, Simon, Waterer, Grant, Hewer, Robert, Friedman, N Deborah, Wark, Peter A., Simpson, Graham, Upham, John, Bowler, Simon D., Lessing, Albert, Kotsimbos, Tom and Kelly, Paul M. (2016). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network. Communicable Diseases Intelligence Quarterly Report, 40 (4), E521-E526.
Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., Guo, M., Reddel, H. K., Jenkins, C., Marks, G. B., Thien, F., Rimmer, J., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Wright, C., Bint, M., Yozghatlian, V., Burgess, S., Sivakumaran, P., Yan, K. Y., Kritikos, V., Peters, M., Baraket, M., Aminazad, A., Robinson, P., Jaffe, A. ... Gibson, P. G. (2016). Real-life effectiveness of omalizumab in severe allergic asthma above the recommended dosing range criteria. Clinical and Experimental Allergy, 46 (11), 1407-1415. doi: 10.1111/cea.12774
Lynch, Jason P., Werder, Rhiannon B., Simpson, Jennifer, Loh, Zhixuan, Zhang, Vivian, Haque, Ashraful, Spann, Kirsten, Sly, Peter D., Mazzone, Stuart B., Upham, John W. and Phipps, Simon (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity. Journal of Allergy and Clinical Immunology, 138 (5), 1326-1337. doi: 10.1016/j.jaci.2016.02.039
Wurzel, Danielle F., Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W., Petsky, Helen L., Smith-Vaughan, Heidi, Masters, Brent, Buntain, Helen and Chang, Anne B. (2016). Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis. Chest, 150 (5), 1101-1108. doi: 10.1016/j.chest.2016.06.030
Navarro, Severine, Pickering, Darren A., Ferreira, Ivana B., Jones, Linda, Ryan, Stephanie, Troy, Sally, Leech, Andrew, Hotez, Peter J., Zhan, Bin, Laha, Thewarach, Prentice, Roger, Sparwasser, Tim, Croese, John, Engwerda, Christian R., Upham, John W., Julia, Valerie, Giacomin, Paul R. and Loukas, Alex (2016). Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine, 8 (362) 362ra143, 362ra143-362ra143. doi: 10.1126/scitranslmed.aaf8807
Kunarajah, Kuhan, Pena, Olga and Upham, John W. (2016). Understanding the immune and inflammatory response to rhinoviruses: recent advances with relevance to asthma. Current Respiratory Medicine Reviews, 12 (3), 215-224. doi: 10.2174/1573398X12666160909102919
Blyth, C. C., Macartney, K. K., Hewagama, S., Senenayake, S., Friedman, N. D., Simpson, G., Upham, J., Kotsimbos, T., Kelly, P. and Cheng, A. C. (2016). Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2014: the influenza complications alert network (FluCAN). Eurosurveillance, 21 (30), 25-33. doi: 10.2807/1560-7917.ES.2016.21.30.30301
Scott, H. A., Gibson, P. G., Garg, M. L., Upham, J. W. and Wood, L. G. (2016). Sex hormones and systemic inflammation are modulators of the obese-asthma phenotype. Allergy, 71 (7), 1037-1047. doi: 10.1111/all.12891
Revez, J. A., Matheson, M. C., Hui, J., Baltic, S., James, A., Upham, J. W., Dharmage, S., Thompson, P. J., Martin, N. G., Hopper, J. L. and Ferreira, M. A. R. (2016). Identification of STOML2 as a putative novel asthma risk gene associated with IL6R. Allergy, 71 (7), 1020-1030. doi: 10.1111/all.12869
Gibson, P. G., Reddel, H., McDonald, V. M., Marks, G., Jenkins, C., Gillman, A., Upham, J., Sutherland, M., Rimmer, J., Thien, F., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Robinson, P., Wright, C., Yozghatlian, V., Burgess, S., Sivakumaran, P., Jaffe, A., Bowden, J., Wark, P. A., Yan, K. Y., Kritikos, V., Peters, M., Hew, M., Aminazad, A. ... Guo, M. (2016). Effectiveness and response predictors of omalizumab in a severe allergic asthma population with a high prevalence of comorbidities: the Australian Xolair Registry. Internal Medicine Journal, 46 (9), 1054-1062. doi: 10.1111/imj.13166
Simpson, Jodie L., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Jia, Guiquan, Holweg, Cecile T. J. and Gibson, Peter G. (2016). Periostin levels and eosinophilic inflammation in poorly-controlled asthma. BMC Pulmonary Medicine, 16 (1) 67, 67.1-67.7. doi: 10.1186/s12890-016-0230-4
Upham, John W. and Gleeson, Sarah J. (2016). Combination long acting bronchodilators for COPD. Medicine Today, 17 (4), 73-74.
Upham, John W. and Sly, Peter D. (2016). Vitamin D in asthma: is the golden bullet losing its luster?. American Journal of Respiratory and Critical Care Medicine, 193 (6), 598-600. doi: 10.1164/rccm.201511-2213ED
Simpson, Jodie L., Daly, Joshua, Baines, Katherine J., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Hugenholtz, Philip, Willner, Dana and Gibson, Peter G. (2016). Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma. European Respiratory Journal, 47 (3), 792-800. doi: 10.1183/13993003.00405-2015
Chang, Anne B., Upham, John W., Masters, I. Brent, Redding, Gregory R., Gibson, Peter G., Marchant, Julie M. and Grimwood, Keith (2016). Protracted bacterial bronchitis: the last decade and the road ahead. Pediatric Pulmonology, 51 (3), 225-242. doi: 10.1002/ppul.23351
Simpson, Jodie L., Carroll, Melanie, Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Gibson, Peter G. and Upham, John W. (2016). Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids. Chest, 149 (3), 704-713. doi: 10.1016/j.chest.2015.12.018
Hodge, Sandra, Upham, John W., Pizzutto, Susan, Petsky, Helen L., Yerkovich, Stephanie, Baines, Katherine J., Gibson, Peter, Simpson, Jodie L., Buntain, Helen, Chen, Alice C. H., Hodge, Greg and Chang, Anne B. (2016). Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?. Chest, 149 (2), 508-515. doi: 10.1016/j.chest.2015.10.066
Pizzutto, Susan J., Upham, John W., Yerkovich, Stephanie T. and Chang, Anne B. (2016). Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis(Review). Cochrane Database of Systematic Reviews, 2016 (1) CD007525. doi: 10.1002/14651858.CD007525.pub3
Hodge, S., Hodge, G., Simpson, J. L., Yang, I. A., Upham, J., James, A., Gibson, P. G. and Reynolds, P. N. (2016). Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma. Clinical and Experimental Allergy, 46 (1), 60-70. doi: 10.1111/cea.12634
Xi, Yang, Finlayson, Arvid, White, Oliva J., Carroll, Melanie L. and Upham, John W. (2015). Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?. Clinical and Translational Immunology, 4 (10) e46, e46. doi: 10.1038/cti.2015.27
Cheng, Allen C., Holmes, Mark, Senenayake, Sanjaya, Dwyer, Dominic E., Hewagama, Saliya, Korman, Tony, Irving, Louis, Brown, Simon, Waterer, Grant, Hunter, Cameron, Friedman, N. Deborah, Wark, Peter, Simpson, Graham, Upman, John, Bowler, Simon, Macartney, Kristine, Blyth, Christopher, Kotsimbos, Tom and Kelly, Paul (2015). Influenza epidemiology in adults admitted to sentinel Australian hospitals in 2014: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence Quarterly Report, 39 (3), E355-E360.
Hodge, G., Upham, J. W., Chang, A. B., Baines, K. J., Yerkovich, S. T., Pizzutto, S. J. and Hodge, S. (2015). Increased peripheral blood pro-inflammatory/cytotoxic lymphocytes in children with bronchiectasis. PLoS One, 10 (8) e0133695, e0133695. doi: 10.1371/journal.pone.0133695
Pizzutto, Susan J., Upham, John W., Yerkovich, Stephanie T. and Chang, Anne B. (2015). High pulmonary levels of IL-6 and IL-1β in children with chronic suppurative lung disease are associated with low systemic IFN-γ production in response to non-typeable Haemophilus influenzae. PLoS One, 10 (6) e0129517, e0129517-e0129517. doi: 10.1371/journal.pone.0129517
Scott, Hayley A., Latham, Jennifer R., Callister, Robin, Pretto, Jeffrey J., Baines, Katherine, Saltos, Nick, Upham, John W. and Wood, Lisa G. (2015). Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma. Annals of Allergy, Asthma and Immunology, 114 (6), 470-479. doi: 10.1016/j.anai.2015.04.002
Frith, Peter A., Thompson, Philip J., Ratnavadivel, Rajeev, Chang, Catherina L., Bremner, Peter, Day, Peter, Frenzel, Christina, Kurstjens, Nicol, Waddell, Ainslie, Daniel, Alexander, Khoussousi, Alireza, Springfield, Andrew, Veale, Andrew, Graham, Anthony Neil, Gallagher, Brad, Pande, Braj Raj, O'Kane, Brendan, Jones, Christopher, Baldi, Claudio, Helm, Colin, O'Dochartaigh, Conor, Chambers, Daniel, Quinn, Dean, Yull, Derek, Karthigesu, Dhanalakshi, Then, Edward, Graham, Frank, Faigenbaum, Fred, Geddam, Geetha ... Hess, Zofia (2015). Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: The GLISTEN study - a randomised controlled trial. Thorax, 70 (6), 519-527. doi: 10.1136/thoraxjnl-2014-206670
Wong, K.J, Timbrell, Victoria L., Xi, Y, Upham, J.W, Collins, A.M and Davies, J.M (2015). IgE+ B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis. Allergy: European Journal of Allergy and Clinical Immunology, 70 (4), 420-428. doi: 10.1111/all.12563
Pizzutto, Susan J., Yerkovich, Stephanie T., Upham, John W., Hales, Belinda J., Thomas, Wayne R. and Chang, Anne B. (2015). Improving immunity to Haemophilus influenzae in children with chronic suppurative lung disease. Vaccine, 33 (2), 321-326. doi: 10.1016/j.vaccine.2014.11.024
Chang, Anne B., Grimwood, Keith, Gibson, Peter G. and Upham, John W. (2015). PBB: definition, mechanisms, and treatment. The Lancet Respiratory Medicine, 3 (10), 743-744. doi: 10.1016/S2213-2600(15)00243-X
Chang, Anne B., Marsh, Robyn L., Upham, John W., Hoffman, Lucas R., Smith-Vaughan, Heidi, Holt, Deborah, Toombs, Maree, Byrnes, Catherine, Yerkovich, Stephanie T., Torzillo, Paul J., O'Grady, Kerry-Ann F. and Grimwood, Keith (2015). Toward making inroads in reducing the disparity of lung health in Australian Indigenous and New Zealand Maori children. Frontiers in Pediatrics, 3 (FEB) 9, 9. doi: 10.3389/fped.2015.00009
Gao, Peng, Gibson, Peter G., Baines, Katherine J., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Zhang, Jie and Simpson, Jodie L. (2015). Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1 beta. Respiratory Research, 16 (5) 5, 5. doi: 10.1189/s12931-014-0163-5
Baines, Katherine J., Upham, John W., Yerkovich, Stephanie T., Chang, Anne B., Marchant, Julie M., Carroll, Melanie, Simpson, Jodie L. and Gibson, Peter G. (2014). Mediators of neutrophil function in children with protracted bacterial bronchitis. Chest, 146 (4), 1013-1020. doi: 10.1378/chest.14-0131
Pritchard, Antonia L., White, Olivia J., Burel, Julie G., Carroll, Melanie L., Phipps, Simon and Upham, John W. (2014). Asthma is associated with multiple alterations in anti-viral innate signalling pathways. PLoS One, 9 (9) 0106501, e106501.1-e106501.11. doi: 10.1371/journal.pone.0106501
Zhang, X. -Y., Simpson, J. L., Powell, H., Yang, I. A., Upham, J. W., Reynolds, P. N., Hodge, S., James, A. L., Jenkins, C., Peters, M. J., Lin, J. -T. and Gibson, P. G. (2014). Full blood count parameters for the detection of asthma inflammatory phenotypes. Clinical and Experimental Allergy, 44 (9), 1137-1145. doi: 10.1111/cea.12345
Pizzutto, Susan J., Yerkovich, Stephanie T., Upham, John W., Hales, Belinda J., Thomas, Wayne R. and Chang, Anne B. (2014). Children with chronic suppurative lung disease have a reduced capacity to synthesize interferon-gamma in vitro in response to non-typeable Haemophilus influenzae. PLoS One, 9 (8) e104236, e104236.1-e104236.10. doi: 10.1371/journal.pone.0104236
Wurzel, D.F., Mackay, I.M., Marchant, J.M., Wang, C.Y.T., Yerkovich, S.T., Upham, J.W., Smith-Vaughan, H.C., Petsky, H.L. and Chang, A.B. (2014). Adenovirus species C is associated with chronic suppurative lung diseases in children. Clinical Infectious Diseases, 59 (1), 34-40. doi: 10.1093/cid/ciu225
Cheng, Allen C., Dwyer, Dominic E., Holmes, Mark, Irving, Louis B., Brown, Simon G. A., Waterer, Grant W., Korman, Tony M., Hunter, Cameron, Hewagama, Saliya, Friedman, Nadia D., Wark, Peter A., Simpson, Graham, Upham, John W., Bowler, Simon D., Senenayake, Sanjaya N., Kotsimbos, Tom C. and Kelly, Paul M. (2014). Influenza epidemiology, vaccine coverage and vaccine effectiveness in sentinel Australian hospitals in 2013: the Influenza Complications Alert Network. Communicable diseases intelligence quarterly report, 38 (2), E143-E149.
Wurzel, D.F., Marchant, J.M., Yerkovich, S.T., Upham, J.W., Mackay, I.M., Masters, I.B. and Chang, A.B. (2014). Prospective characterization of protracted bacterial bronchitis in children. Chest, 145 (6), 1271-1278. doi: 10.1378/chest.13-2442
Simpson, Jodie L., Gibson, Peter G., Yang, Ian A., Upham, John, James, Alan, Reynolds, Paul N., Hodge, Sandra and AMAZES Study Research Group (2014). Altered sputum granzyme B and granzyme B/proteinase inhibitor-9 in patients with non-eosinophilic asthma. Respirology, 19 (2), 280-287. doi: 10.1111/resp.12213
Timbrell, Victoria L., Riebelt, Lindsay, Simmonds, Claire, Solley, Graham, Smith, William B., McLean-Tooke, Andrew, Van Nunen, Sheryl, Smith, Peter K., Upham, John W., Langguth, Daman and Davies, Janet M. (2014). An immunodiagnostic assay for quantitation of specific EgE to the major pollen allergen component, Pas n 1, of the subtropical Bahia grass. International Archives of Allergy and Immunology, 165 (4), 219-228. doi: 10.1159/000369341
Spann, Kirsten M., Loh, Zhixuan, Lynch, Jason P., Ullah, Ashik, Zhang, Vivian, Baturcam, Engin, Werder, Rhiannon B., Khajornjiraphan, Natthida, Rudd, Penny, Loo, Yeuh-Ming, Suhrbier, Andreas, Gale Jr., Michael, Upham, John W. and Phipps, Simon (2014). IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice. American Journal of Pathology, 184 (6), 1795-1806. doi: 10.1016/j.ajpath.2014.02.026
Georas, Steve N. and Upham, John (2014). Environmental exposures and innate immunity in the lung. Journal of Environmental Immunology and Toxicology, 2 (1), 1-3. doi: 10.7178/jeit.25
Lynch, Jason P., Mazzone, Stuart B., Rogers, Matthew J., Arikkatt, Jaisy J., Loh, Zhixuan, Pritchard, Antonia L., Upham, John W. and Phipps, Simon (2014). The plasmacytoid dendritic cell: a cell at the cross-roads in asthma. European Respiratory Journal, 43 (1), 264-275. doi: 10.1183/09031936.00203412
Nath, K.D., Burel, J.G., Shankar, V., Pritchard, A.L., Towers, M., Looke, D., Davies, J.M. and Upham, J.W. (2013). Clinical factors associated with the humoral immune response to influenza vaccination in chronic obstructive pulmonary disease. International Journal of COPD, 9 (1), 51-56. doi: 10.2147/COPD.S53590
Cheng, Allen C, Brown, Simon, Waterer, Grant, Holmes, Mark, Senenayake, Sanjaya, Friedman, N Deborah, Hewagama, Saliya, Simpson, Graham, Wark, Peter, Upham, John, Korman, Tony, Dwyer, Dominic, Wood-Baker, Richard, Irving, Louis, Bowler, Simon, Kotsimbos, Tom and Kelly, Paul (2013). Influenza epidemiology, vaccine coverage and vaccine effectiveness in sentinel Australian hospitals in 2012: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence Quarterly Report, 37 (3), E246-E252.
Cheng, Allen C., Brown, Simon, Waterer, Grant, Holmes, Mark, Senenayake, Sanjaya, Friedman, N Deborah, Hewagama, Saliya, Simpson, Graham, Wark, Peter, Upham, John, Korman, Tony, Dwyer, Dominic, Wood-Baker, Richard, Irving, Louis, Bowler, Simon, Kotsimbos, Tom and Kelly, Paul (2013). Influenza epidemiology, vaccine coverage and vaccine effectiveness in sentinel Australian hospitals in 2012: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence Quarterly Report, 37 (3), E246-E252.
Cheng, Allen C., Holmes, Mark, Irving, Louis B., Brown, Simon G. A., Waterer, Grant W., Korman, Tony M., Friedman, N. Deborah, Senanayake, Sanjaya, Dwyer, Dominic E., Brady, Stephen, Simpson, Grahame, Wood-Baker, Richard, Upham, John, Paterson, David, Jenkins, Christine, Wark, Peter, Kelly, Paul M. and Kotsimbos, Tom (2013). Influenza Vaccine Effectiveness against Hospitalisation with Confirmed Influenza in the 2010-11 Seasons: A Test-negative Observational Study. Plos One, 8 (7) e68760, e68760.1-e68760.7. doi: 10.1371/journal.pone.0068760
Liu, Xin, Jin, Lu, Upham, John W. and Roberts, Michael S. (2013). The development of models for the evaluation of pulmonary drug disposition. Expert Opinion On Drug Metabolism & Toxicology, 9 (4), 487-505. doi: 10.1517/17425255.2013.754009
Wurzel D.F., Marchant J.M., Clark J.E., Mackay I.M., Wang C.Y.T., Sloots T.P., Upham J.W., Yerkovich S.T., Masters I.B., Baker P.J., Anderson-James S. and Chang A.B. (2013). Respiratory virus detection in nasopharyngeal aspirate versus bronchoalveolar lavage is dependent on virus type in children with chronic respiratory symptoms. Journal of Clinical Virology, 58 (4), 683-688. doi: 10.1016/j.jcv.2013.09.016
Wurzel, D.F., Marchant, J.M., Clark, J.E., Masters, I.B., Yerkovich, S.T., Upham, J.W. and Chang, A.B. (2013). Wet cough in children: Infective and inflammatory characteristics in broncho-alveolar lavage fluid. Pediatric Pulmonology, 49 (6), 561-568. doi: 10.1002/ppul.22792
Simpson, J. L., Gibson, P. G., Yang, I. A., Upham, J., James, A., Reynolds, P. N., Hodge, S. and AMAZES Study Research Group (2013). Impaired macrophage phagocytosis in non-eosinophilic asthma. Clinical and Experimental Allergy, 43 (1), 29-35. doi: 10.1111/j.1365-2222.2012.04075.x
Pizzutto, Susan J., Grimwood, Keith, Bauert, Paul, Schutz, Kobi L., Yerkovich, Stephanie T., Upham, John W. and Chang, Anne B. (2013). Bronchoscopy contributes to the clinical management of indigenous children newly diagnosed with bronchiectasis. Pediatric Pulmonology, 48 (1), 67-73. doi: 10.1002/ppul.22544
Pritchard, Antonia L., White, Olivia J., Burel, Julie G. and Upham, John W. (2012). Innate interferons inhibit allergen and microbial specific T(H)2 responses. Immunology and Cell Biology, 90 (10), 974-977. doi: 10.1038/icb.2012.39
Chang, Anne B., Yerkovich, Stephanie T., Gibson, Peter G., Anderson-James, Sophie, Petsky, Helen L., Carroll, Melanie L., Masters, I. Brent, Marchant, Julie M., Wurzel, Danielle and Upham, John W. (2012). Pulmonary Innate Immunity in Children with Protracted Bacterial Bronchitis. Journal of Pediatrics, 161 (4), 621-625.e1. doi: 10.1016/j.jpeds.2012.03.049
Rate, Angela, Bosco, Anthony, McKenna, Kathy L., Holt, Patrick G. and Upham, John W. (2012). Airway epithelial cells condition dendritic cells to express multiple immune surveillance genes. PLoS One, 7 (9 Article No. e44941) e44941, e44941. doi: 10.1371/journal.pone.0044941
Yerkovich, Stephanie T., Hales, Belinda J., Carroll, Melanie L., Burel, Julie G., Towers, Michelle A., Smith, Daniel J., Thomas, Wayne R. and Upham, John W. (2012). Reduced rhinovirus-specific antibodies are associated with acute exacerbations of chronic obstructive pulmonary disease requiring hospitalisation. Bmc Pulmonary Medicine, 12 (Article No.37) 37, 37-1-37-7. doi: 10.1186/1471-2466-12-37
Yerkovich, Stephanie T., Chang, Anne B., Carroll, Melanie L., Petsky, Helen L., Scrivener, Greta and Upham, John W. (2012). Soluble receptor for advanced glycation end products (sRAGE) is present at high concentrations in the lungs of children and varies with age and the pattern of lung inflammation. Respirology, 17 (5), 841-846. doi: 10.1111/j.1440-1843.2012.02174.x
Pritchard, Antonia L., Carroll, Melanie L., Burel, Julie G., White, Olivia J., Phipps, Simon and Upham, John W. (2012). Innate IFNs and plasmacytoid dendritic cells constrain Th2 cytokine responses to rhinovirus: A regulatory mechanism with relevance to asthma. Journal of Immunology, 188 (12), 5898-5905. doi: 10.4049/jimmunol.1103507
Clifford, Holly D., Yerkovich, Stephanie T., Khoo, Siew-Kim, Zhang, Guicheng, Upham, John, Le Souef, Peter N., Richmond, Peter and Hayden, Catherine M. (2012). TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles virus and vaccine in vaccinated infants. Human Immunology, 73 (6), 677-685. doi: 10.1016/j.humimm.2012.03.004
Clifford, Holly D., Yerkovich, Stephanie T., Khoo, Siew-Kim, Zhang, Guicheng, Upham, John, Le Souef, Peter N., Richmond, Peter and Hayden, Catherine M. (2012). Toll-like receptor 7 and 8 polymorphisms: associations with functional effects and cellular and antibody responses to measles virus and vaccine. Immunogenetics, 64 (3), 219-228. doi: 10.1007/s00251-011-0574-0
Burel, Julie G., Nath, Karthik, Pritchard, Antonia L., White, Olivia J., Davies, Janet M., Towers, Michelle, Looke, David and Upham, John W. (2012). Evaluation of Immune Responses to Influenza Vaccination in Chronic Obstructive Pulmonary Disease. Journal of Vaccines & Vaccination, 4 (6), 1-7. doi: 10.4172/2157-7560.S4-001
Davies, Janet M., Li, Hongzhuo, Green, Melissa, Towers, Michelle and Upham, John W. (2012). Subtropical grass pollen allergens are important for allergic respiratory diseases in subtropical regions. Clinical and Translational Allergy, 2 (4) 4, 1-10. doi: 10.1186/2045-7022-2-4
Davies, Janet M., Carroll, Melanie L., Li, Hongzhou, Poh, Alisa M., Kirkegard, Darren, Towers, Michelle and Upham, John W. (2011). Budesonide and formoterol reduce early innate anti-viral immune responses in vitro. PLoS One, 6 (11) e27898, e27898.1-e27898.8. doi: 10.1371/journal.pone.0027898
Cheng, Allen C., Kotsimbos, Tom, Kelly, Heath A., Irving, Louis B., Bowler, Simon D., Brown, Simon G.A., Holmes, Mark, Jenkins, Christine R., Thompson, Philip, Simpson, Graham, Wood-Baker, Richard, Senanayake, Sanjaya N., Brady, Stephen J., Paterson, David L., Wark, Peter A., Upham, John W., Korman, Tony M., Dwyer, Dominic E., Waterer, Grant W. and Kelly, Paul M. (2011). Effectiveness of H1N1/09 monovalent and trivalent influenza vaccines against hospitalization with laboratory-confirmed H1N1/09 influenza in Australia: A test-negative case control study. Vaccine, 29 (43), 7320-7325. doi: 10.1016/j.vaccine.2011.07.087
Upham, J.W., Smith, D. J. and Yerkovich, S.T. (2011). Correspondence: Does RAGE protect smokers from COPD?. The European Respiratory Journal, 38 (3), 744-744. doi: 10.1183/09031936.00066311
Wurzel, Danielle, Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W., Masters, I. Brent and Chang, Anne B. (2011). Short courses of antibiotics for children and adults with bronchiectasis (Review). Cochrane Database of Systematic Reviews (6). doi: 10.1002/14651858.CD008695.pub2
Upham, John W. and James, Alan L. (2011). Remission of asthma: the next therapeutic frontier?. Pharmacology & Therapeutics, 130 (1), 38-45. doi: 10.1016/j.pharmthera.2011.01.002
Smith, D. J., Yerkovich, S. T., Towers, M. A., Carroll, M. L., Thomas, R. and Upham, J. W. (2011). Reduced soluble receptor for advanced glycation end-products in COPD. European Respiratory Journal, 37 (3), 516-522. doi: 10.1183/09031936.00029310
Davies, Janet M., Voskamp, Astrid, Dang, Thanh D., Pettit, Benjamin, Loo, Dorothy, Petersen, Arnd, Hill, Michelle M., Upham, John W., Rolland, Jennifer M. and O'Hehir, Robyn E. (2011). The dominant 55kDa allergen of the subtropical Bahia grass (Paspalum notatum) pollen is a group 13 pollen allergen, Pas n 13. Molecular Immunology, 48 (6-7), 931-940. doi: 10.1016/j.molimm.2010.12.013
Davies, J.M., Dang, T.D., Voskamp, A., Drew, A.C., Biondo, M., Phung, M., Upham, J.W., Rolland, J.M. and O'Hehir, R.E. (2011). Functional immunoglobulin E cross-reactivity between Pas n 1 of Bahia grass pollen and other group 1 grass pollen allergens. Clinical and Experimental Allergy, 41 (2), 281-291. doi: 10.1111/j.1365-2222.2010.03670.x
Carroll, Melanie L., Yerkovich, Stephanie T., Pritchard, Antonia L., Davies, Janet M. and Upham, John W. (2010). Adaptive immunity to rhinoviruses: Sex and age matter. Respiratory Research, 11 (1) 184, 184-1-184-7. doi: 10.1186/1465-9921-11-184
Upham, JW and Pritchard, A (2010). Are rhinoviral proteinases responsible for mixed T(H)1 and T(H)2 immunity in chronic obstructive pulmonary disease?. Journal of Allergy and Clinical Immunology, 126 (6), 1318-1318. doi: 10.1016/j.jaci.2010.07.009
Strickland, DH, Upham, JW and Holt, PG (2010). Epithelial-dendritic cell interactions in allergic disorders. Current Opinion in Immunology, 22 (6), 789-794. doi: 10.1016/j.coi.2010.10.019
Sturges, Nina C., Wikström, Matthew E., Winfield, Kaye R., Gard, Samantha E., Brennan, Siobhain, Sly, Peter D. and Upham, John W. (2010). Monocytes From Children With Clinically Stable Cystic Fibrosis Show Enhanced Expression of Toll-Like Receptor 4. Pediatric Pulmonology, 45 (9), 883-889. doi: 10.1002/ppul.21230
Reddel, Helen K., Upham, John W., Salvi, Sundeep S. and Yang, Ian A. (2010). Year-in-review 2009: Asthma, COPD and airway biology. Respirology, 15 (2), 365-376. doi: 10.1111/j.1440-1843.2009.01702.x
Pizzutto, Susan J., Upham, John W., Yerkovich, Stephanie T. and Chang, Anne B. (2010). Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis. Cochrane Database of Systematic Reviews, 4 (4) ARTN CD007525, CD007525-1-CD007525-18. doi: 10.1002/14651858.CD007525.pub2
Roponen, M., Yerkovich, S. T., Hollams, E., Sly, P. D., Holt, P. G. and Upham, J. W. (2010). Toll-like receptor 7 function is reduced in adolescents with asthma. European Respiratory Journal, 35 (1), 64-71. doi: 10.1183/09031936.00172008
Upham, John W., Zhang, Guicheng, Rate, Angela, Yerkovich, Stephanie T., Kusel, Merci, Sly, Peter D. and Holt, Patrick G. (2009). Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing. Journal of Allergy and Clinical Immunology, 124 (4), 707-713. doi: 10.1016/j.jaci.2009.07.009
Brennan, S., Sly, P. D., Gangell, C. L., Sturges, N., Winfield, K., Wikstrom, M., Gard, S. and Upham, J. W. (2009). Alveolar macrophages and the CC chemokines are increased in children with cystic fibrosis. The European Respiratory Journal, 34 (3), 655-661. doi: 10.1183/09031936.00178508
Pizzutto, Susan J., Upham, John W., Yerkovich, Stephanie T. and Chang, Anne B. (2009). Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis (Protocol). Cochrane Database of Systematic Reviews (1) CD007525, CD007525.1-CD007525.7. doi: 10.1002/14651858.CD007525
Yerkovich, Stephanie T. and Upham, John W. (2009). Reply to "Thrombomodulin: a novel player in allergic asthma”. Journal of Allergy and Clinical Immunology, 123 (5), 1192-1193. doi: 10.1016/j.jaci.2009.01.046
Rate, A., Upham, J. W., Bosco, A., McKenna, K. L. and Holt, P. G. (2009). Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: Implications for the pathogenesis of infectious and allergic airway disease. Journal of Immunology, 182 (1), 72-83. doi: 10.4049/jimmunol.182.1.72
Yerkovich, Stephanie T., Roponen, Marjut, Smith, Miranda E., McKenna, Kathy, Bosco, Anthony, Subrata, Lily S., Mamessier, Emilie, Wikstrom, Matthew E., Le Souef, Peter, Sly, Peter D., Holt, Patrick D. and Upham, John. W. (2009). Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a T(H)2-skewed immune response. Journal of Allergy and Clinical Immunology, 123 (1), 209-216. doi: 10.1016/j.jaci.2008.09.009
Upham, John and Yerkovich, Stephanie T. (2009). Regulation of urokinase receptor expression: Interpreting data in the absence of statistics. American Journal of Respiratory And Critical Care Medicine, 180 (6), 583-583. doi: 10.1164/ajrccm.180.6.583
Tulic, Meri K., Hurrelbrink, Robert j,, Prele, Cecilia M., Laing, Ingrid A,, Upham, John W., Le Souef, Peter, Sly, Peter D. and Holt, Patrick G. (2007). TLR4 Polymorphisms Mediate Impaired Responses to Respiratory Syncytial Virus and Lipopolysaccharide1. Journal of Immunology, 179 (1), 132-140. doi: 10.4049/jimmunol.179.1.132
Yerkovich, S., Wickstrom, M. E., Suriyaarachchi, D., Prescott, S. L., Upham, J. and Holt, P. G. (2007). Postnatal development of monocyte cytokine responses to bacterial lipopolysaccharide. Pediatric Research, 62 (5), 547-552. doi: 10.1203/PDR.0b013e3181568105
Upham, J. W. and Stick, S. M. (2006). Interactions Between Airway Epithelial Cells and Dendritic Cells: Implications for the Regulation of Airway Inflammation. Current Drug Targets, 7 (5), 541-545. doi: 10.2174/138945006776818647
Taylor, Rebecca C., Richmond, Peter and Upham, John W. (2006). Toll-like receptor 2 ligands inhibit Th2 responses to mite allergen. Journal of Allergy and Clinical Immunology, 117 (5), 1148-1154. doi: 10.1016/j.jaci.2006.02.014
Yerkovich, Stephanie T., Rate, Angela and Upham, John W. (2006). Dendritic cells in allergic disease - innocent bystanders or prime suspects?. Allergy & Clinical Immunology International, 18 (2), 71-75. doi: 10.1027/0838-1925.18.2.71
Upham, John W., Rate, Angela, Rowe, Julie, Kusel, Merci, Sly, Peter D. and Holt, Patrick G. (2006). Dendritic cell immaturity during infancy restricts the capacity to express vaccine-specific T-cell memory. Infection and Immunity, 74 (2), 1106-1112. doi: 10.1128/IAI.74.2.1106-1112.2006
Holt, Patrick G., Upham, John W. and Sly, Peter D. (2005). Contemporaneous maturation of immunologic and respiratory functions during early childhood: Implications for development of asthma prevention strategies. Journal of Allergy and Clinical Immunology, 116 (1), 16-24. doi: 10.1016/j.jaci.2005.04.017
Upham, John W. and Holt, Patrick G. (2005). Environment and development of atopy. Current Opinion in Allergy and Clinical Immunology, 5 (2), 167-172. doi: 10.1097/01.all.0000162310.79555.ed
Kedda, M-A., Lose, F., Duffy, D., Bell, E., Thompson, P. J. and Upham, J. (2005). The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population. Thorax, 60 (3), 211-214. doi: 10.1136/thx.2004.028449
Prescott, S. L., Taylor, A., Roper, J., Wahdan, A., Noakes, P., Thornton, C., Dunstan, J. and Upham, J. W. (2005). Maternal reactivity to fetal alloantigens is related to newborn immune responses and subsequent allergic disease. Clinical and Experimental Allergy, 35 (4), 417-425. doi: 10.1111/j.1365-2222.2005.02171.x
Prescott, S. L., Irwin, S., Taylor, A., Roper, J., Dunstan, J., Upham, J. W., Burgner, D. and Richmond, P. (2005). Cytosine–phosphate–guanine motifs fail to promote T-helper type 1-polarized responses in human neonatal mononuclear cells. Clinical and Experimental Allergy, 35 (3), 358-366. doi: 10.1111/j.1365-2222.2005.02187.x
Upham, John W., Holt, Patrick G., Taylor, Angie, Thornton, Catherine A. and Prescott, Susan L. (2004). HLA-DR expression on neonatal monocytes is associated with allergen-specific immune responses. Journal of Allergy and Clinical Immunology, 114 (5), 1202-1208. doi: 10.1016/j.jaci.2004.06.051
Thornton, C. A., Upham, J. W., Wikstrom, M. E., Holt, B. J., White, G. P., Sharp, M. J., Sly, P. D. and Holt, P. G. (2004). Functional maturation of CD4 +CD25 +CTLA4 +CD45RA + T regulatory cells in human neonatal T cell responses to environmental antigens/allergens. Journal of Immunology, 173 (5), 3084-3092. doi: 10.4049/jimmunol.173.5.3084
Long, Julie A., Fogel-Petrovic, Mirjana, Knight, Darryl A., Thompson, Philip J. and Upham, John W. (2004). Higher Prostaglandin E2 Production by Dendritic Cells from Subjects with Asthma Compared with Normal Subjects. American Journal of Respiratory and Critical Care Medicine, 170 (5), 485-491. doi: 10.1164/rccm.200311-1595OC
Fogel-Petrovic, Mirjana, Long, Julie A., Knight, Darryl A., Thompson, Philip J. and Upham, John W. (2004). Activated human dendritic cells express inducible cyclo-oxygenase and synthesize prostaglandin E2 but not prostaglandin D2. Immunology and Cell Biology, 82 (1), 47-54. doi: 10.1111/j.1440-1711.2004.01213.x
Holt, P. G. and Upham, J. W. (2004). The Role of Dendritic Cells in Asthma. Current Opinion In Allergy And Clinical Immunology, 4 (1), 39-44. doi: 10.1097/00130832-200402000-00009
Upham, John W. and Stumbles, Philip A. (2003). Why are dendritic cells important in allergic diseases of the respiratory tract?. Pharmacology and Therapeutics, 100 (1), 75-87. doi: 10.1016/S0163-7258(03)00094-9
Stumbles, Philip A., Upham, John W. and Holt, Patrick G. (2003). Airway dendritic cells: Co-ordinators of immunological homeostasis and immunity in the respiratory tract. APMIS, 111 (7-8), 741-755. doi: 10.1034/j.1600-0463.2003.11107806.x
Upham, John W. (2003). The Role of Dendritic Cells in Immune Regulation and Allergic Airway Inflammation. Respirology, 8 (2), 140-148. doi: 10.1046/j.1440-1843.2003.00465.x
Prescott, S. L., Taylor, A., King, B., Dunstan, J., Upham, J. W., Thornton, C. A. and Holt, P. G. (2003). Neonatal interleukin-12 capacity is associated with variations in allergen-specific immune responses in the neonatal and postnatal periods. Clinical and Experimental Allergy, 33 (5), 566-572. doi: 10.1046/j.1365-2222.2003.01659.x
Mukherjee, Sutapa, Upham, John W., Ramshaw, Ian, Bundell, Christine, van Bruggen, Ivonne, Robinson, Bruce W. S. and Nelson, Delia J. (2003). Dendritic cells infected with a vaccinia virus interleukin-2 vector secrete high levels of IL-2 and can become efficient antigen presenting cells that secrete high levels of the immunostimulatory cytokine IL-12. Cancer Gene Therapy, 10 (8), 591-602. doi: 10.1038/sj.cgt.7700604
Upham, John W., Lee, Peter T., Holt, Barbara J., Heaton, Tricia, Prescott, Susan L., Sharp, Mary J., Sly, Peter D. and Holt, Patrick G. (2002). Development of Interleukin-12-Producing Capacity throughout Childhood. Infection and Immunity, 70 (12), 6583-6588. doi: 10.1128/IAI.70.12.6583-6588.2002
Fogel, Mirjana, Long, Julie A., Thompson, Philip J. and Upham, John W. (2002). Dendritic cell maturation and IL-12 synthesis induced by the synthetic immune-response modifier S-28463. Journal of Leukocyte Biology, 72 (5), 932-938.
Fogel, Mirjana, Long, Julie A., Thompson, Philip J. and Upham, John W. (2002). Dendritic cell maturation and IL-12 synthesis induced by the synthetic immune-response modifier S-28463. Journal of Leukocyte Biology, 72 (5), 932-938.
Stumbles, Philip A., Upham, John W. and Nelson, Delia J. (2002). Basic Science Funding in Australia: Lessons from the EU. Nature Immunology, 3 (10), 885-885. doi: 10.1038/ni1002-885
Lundahl, J., Sehmi, R., Moshfegh, A., Hayes, L., Howie, K., Upham, J. and Denburg, J. A. (2002). Distinct Phenotypic Adhesion Molecule Expression on Human Cord Blood Progenitors During Early Eosinophilic Commitment: Upregulation of β7 Integrins. Scandinavian Journal of Immunology, 56 (2), 161-167. doi: 10.1046/j.1365-3083.2002.01117.x
Upham, J. W., Wood, L. J., Denburg, J. A. and Byrne, P. M. (2002). Rapid response of circulating myeloid dendritic cells to inhaled allergen in asthmatic subjects. Clinical And Experimental Allergy, 32 (6), 818-823. doi: 10.1046/j.1365-2222.2002.01375.x
Upham, John W., Sehmi, Roma, Hayes, Lisa M., Howie, Karen, Lundahl, Joachim and Denburg, Judah A. (2002). Retinoic Acid Modulates IL-5 Receptor Expression and Selectively Inhibits Eosinophil-Basophil Differentiation of Hemopoietic Progenitor Cells. Journal of Allergy and Clinical Immunology, 109 (2), 307-313. doi: 10.1067/mai.2002.121527
Jahnsen, F. L., Moloney, E. D., Hogan, T., Upham, J. W., Burke, C. M. and Holt, P. G. (2001). Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge. Thorax, 56 (11), 823-826. doi: 10.1136/thorax.56.11.823
Upham, J. W., Lundahl, J., Liang, H., Denburg, J. A., O'Byrne, P. M. and Snider, D. P. (2000). Simplified quantitation of myeloid dendritic cells in peripheral blood using flow cytometry. Cytometry, 40 (1), 50-59. doi: 10.1002/(SICI)1097-0320(20000501)40:1<50::AID-CYTO7>3.0.CO;2-P
Upham, John, Hayes, Lisa, Sehmi, Roma and Denburg, Judah (1999). Retinoic acid selectively inhibits il-5 receptor expression during progenitor cell differentiation. Respirology, 4 (SUPPL. 1)
Upham, John, Denburg, Judah and O'Byrne, Paul (1999). Circulating dendritic cells and asthma: Rapid changes following inhaled allergen. Respirology, 4 (SUPPL. 1)
Upham, John, Hayes, Lisa, Lundahl, Joachim, Sehmi, Roma and Denburg, Judah (1999). Reduced expression of gm-csf receptor on cord blood progenitor cells from neonates at risk for atopy. Respirology, 4 (SUPPL. 1)
Upham, John W., Hayes, Lisa M., Lundahl, Joachim, Sehmi, Roma and Denburg, Judah A. (1999). Reduced expression of hemopoietic cytokine receptors on cord blood progenitor cells in neonates at risk for atopy. Journal of Allergy and Clinical Immunology, 104 (2), 370-375. doi: 10.1016/S0091-6749(99)70381-7
Holt, P. G. and Upham, J. W. (1998). Inhibition of T cell proliferation by human alveolar macrophages - Authors' reply. Thorax, 53 (5), 437-437.
Upham, J. W., Strickland, D. H., Robinson, B. W. S. and Holt, P. G. (1997). Selective inhibition of T cell proliferation but not expression of effector function by human alveolar macrophages. Thorax, 52 (9), 786-795. doi: 10.1136/thx.52.9.786
Upham, J. W., Garlepp, M. J., Musk, A. W. and Robinson, B. W. S. (1995). Malignant mesothelioma: new insights into tumour biology and immunology as a basis for new treatment approaches. Thorax, 50 (8), 887-893. doi: 10.1136/thx.50.8.887
Upham, J.W., Holt, B.J., Baron-Hay, M.J., Yabuhara, A., Hales, B.J., Thomas, W.R., Loh, R.K., O'Keeffe, P.T., Palmer, L. and Le Souef, P.N. (1995). Inhalant allergen-specific T-cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum-free medium. Clinical and Experimental Allergy, 25 (7), 634-42.
Upham, J. W., Holt, B. J., Baron-Hay, M. J., Yabuhara, A., Hales, B. J., Thomas, W. R., Loh, R. K. S., O'Keeffe, P. T., Palmer, L., Le Souef, P. N., Sly, P. D., Burton, P. R., Robinson, B. W. S. and Holt, P. G. (1995). Inhalant allergen-specific T-cell reactivity is detectable in close to 100% of atopic and normal individuals: Covert responses are unmasked by serum-free medium. Clinical and Experimental Allergy, 25 (7), 634-642. doi: 10.1111/j.1365-2222.1995.tb01111.x
Holt, P. G., O'Keefe, P., Holt, B. J., Upham, J. W., Baron-Hay, M. J., Suphioglu, C., Knox, B., Stewart, G. A., Thomas, W. R. and Sly, P. D. (1995). T-cell 'priming' against environmental allergens in human neonates: Sequential deletion of food antigen reactivity during infancy with concomitant expansion of responses to ubiquitous inhalant allergens. Pediatric Allergy and Immunology, 6 (2), 85-90. doi: 10.1111/j.1399-3038.1995.tb00264.x
Upham, J. W., McMenamin, C., Schon-Hegrad, M. A., Robinson, B. W. S. and Holt, P. G. (1994). Functional analysis of human bronchial mucosal T cells extracted with interleukin-2. American Journal of Respiratory and Critical Care Medicine, 149 (6), 1608-1613. doi: 10.1164/ajrccm.149.6.7911708
Upham, J. W., Musk, A. W., van Hazel, G., Byrne, M. and Robinson, B. W. S. (1993). Interferon alpha and doxorubicin in malignant mesothelioma: a phase II study. Australian and New Zealand Journal of Medicine, 23 (6), 683-687. doi: 10.1111/j.1445-5994.1993.tb04727.x
Upham, J. and Campbell, B. (1992). Utility of squamous cell carcinoma antigen (SCC Ag) as a tumour marker in pulmonary malignancy. Respiratory Medicine, 86 (3), 201-203. doi: 10.1016/S0954-6111(06)80055-7
Upham, J W, Mitchell, C A, Armstrong, J G and Kelly, W T (1992). Investigation of pleural effusion: the role of bronchoscopy. Australian and New Zealand Journal of Medicine, 22 (1), 41-3. doi: 10.1111/j.1445-5994.1992.tb01707.x
Upham, J. W., Mitchell, C. A., Armstrong, J. G. and Kelly, W. T. (1992). Investigation of pleural effusion: the role of bronchoscopy. Australian and New Zealand Journal of Medicine, 22 (1), 41-43. doi: 10.1111/j.1445-5994.1992.tb01707.x
Upham, J. W. (1983). Dystonic reaction to metoclopramide. Medical Journal of Australia, 1 (1), 12-12. doi: 10.5694/j.1326-5377.1983.tb136014.x
Conference Papers
Price, David, Rhee, Chin Kook, Tran, Trung N., Katial, Rohit, Martin, Neil, Peters, Matthew, Denton, Eve, Upham, John W., Bardin, Philip, Cochrane, Belinda, Middleton, Peter G., Reynolds, Paul, Perng, Diahn-Warng, Wang, Hao-Chien, Sheu, Chau-Chyun and Tsai, Ming-Ju (2023). Demographic and clinical characteristics of patients with severe asthma in the Asian pacific region: Data from the International Severe Asthma Registry (ISAR). HOBOKEN: WILEY.
Samaranayake, C., Craigie, M., Bell, P., Mccabe, C., Upham, J., Coucher, J. and Keir, G. (2022). Right heart strain assessment on CTPA following acute pulmonary embolism: interobserver variability between radiologists and thoracic physicians. 2022 ERS International Congress, Barcelona, Spain, 4-6 September 2022. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2022.1823
Jurak, L, Yang, I, Hill, M, Simpson, J and Upham, J (2022). Understanding how azithromycin reduces asthma exacerbations and the underlying mechanisms of macrolides. European Respiratory Society. doi: 10.1183/13993003.congress-2022.4372
Snape, N., Lai, R., Jarnicki, A., Irving, L., Anderson, G., Wood, L. and Upham, J. (2020). Dietary fibre improves antibody responses after influenza vaccine in COPD patients and healthy older people. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell.
Hew, M., McDonald, , Bardin, P., Chung, L., Farah, C., Barnard, A., Cooper, M., Gibson, P. and Upham, J. (2020). Oral corticosteroid use for asthma in Australia. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell .
Wang, R., Moniruzzaman, M., Wang, K., Upham, J. W., McGuckin, M., Phipps, S. and Hasnain, S. Z. (2020). Blocking endogenous IL-22 is associated with reduced viral load and improved lung pathology in respiratory viral infections. International Conference of the American-Thoracic-Society (ATS), Online, 10 November 2020. New York, NY, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6530
Gupta, S., Fricker, M., Xi, Y., Grainge, C., Upham, J. and Simpson, J. (2020). FC Gamma receptor (FCGR) I expression is increased in severe asthma particularly in participants with non-eosinophilic airway inflammation. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, QLD Australia, 27-31 March 2020. Hoboken, NJ USA: Wiley.
Hasnain, S., Wang, R., Taylor, S., Wong, K. Y., Moniruzzaman, M., Upham, J., Spann, K., Mcguckin, M. A., Burr, L. and Phipps, S. (2020). Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777
Upham, J., Murray, L. and Xi, Y. (2020). Factors associated with respiratory infection frequency in healthy and asthmatic adults differ between women and men. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, QLD Australia, 27-31 March 2020. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
Upham, John W., Jackson, David J., Barker, Peter, Newbold, Paul and Cook, William (2019). Baseline predictors of being exacerbation-free during 2 years of benralizumab treatment. European-Respiratory-Society (ERS) International Congress, Madrid, Spain, 28 September - 2 October 2019. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2019.OA5337
Simpson, Jodie, Barker, Daniel, Yang, Ian, Upham, John, Reynolds, Paul, Hodge, Sandra, James, Alan, Jenkins, Christine, Peters, Matthew, Marks, Guy, Baraket, Melissa and Gibson, Peter (2019). Azithromycin add-on therapy reduces airway inflammation and extracellular DNA: An AMAZES sub-study. European-Respiratory-Society (ERS) International Congress, Madrid, Spain, 28 September-2 October 2019. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2019.OA5338
Wang, R., Taylor, S., Moniruzzaman, M., Wong, K., Upham, J., Spann, K., McGuckin, M., Phipps, S. and Hasnain, S. (2019). A novel role of IL-22 in regulating epithelial MHC molecule expression and antigen presentation during viral infection. 17th International Congress of Immunology (IUIS), Beijing, People's Republic of China, 9-23 October 2019. Weinheim, Germany: Wiley.
Kailaivasan, T. H., Nouri, H., Upham, J. and Davies, J. M. (2019). Innate immune interactions of human rhinovirus-16 and grass pollen in grass pollen allergic adults. Congress of the European Academy of Allergy and Clinical Immunology (EAACI), Lisbon Portugal, 1-5 June, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/all.13962
Anderson, G., Irving, L., Jarnicki, A., Upham, J. and Snape, N. (2019). Antibody response to influenza vaccine in chronic obstructive pulmonary disease (COPD). TSANZSRS 2019 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Gold Coast, QLD Australia, 29 March–2 April 2019. Hoboken, NJ United States: Wiley-Blackwell.
Gibson, P., Yang,, Upham, J., Reynolds, P., Hodge, S., James, A., Jenkins, C., Peters, M., Marks, G., Baraket, M., Powell, H. and Simpson, J. (2019). Efficacy of azithromycin in severe asthma. TSANZSRS 2019, Gold Coast, Australia, 29 March–2 April 2019. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13491
Fanning, M., Harvey, E. and Upham, J. (2019). Late discontinuation of omalizumab in severe asthma. TSANZSRS 2019, Gold Coast, Australia, 29 March–2 April 2019. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13490
Snape, N., Jarnicki, A., Irving, L., Anderson, G. P. and Upham, J. W. (2019). Specific Antibody Response to Seasonal Influenza Vaccine in Chronic Obstructive Pulmonary Disease (COPD) and Healthy Older People. International Conference of the American Thoracic Society, Dallas, TX United States, 17-22 May 2019. New York, NY United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7093
Kailaivasan, T., Timbrell, , Solley, G., Smith, W. B., Mclean-Tooke, A., Van Nunen, S., Smith, P. K., Upham, J. W., Langguth, D. and Davies, J. M. (2018). Biogeographical variation in IgE specificity and avidity for subtropical and temperate grass pollen allergens; the multicentre cross-sectional Grass Pollen Allergy Survey (GPAS). Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Munich Germany, May 26-30, 2018. HOBOKEN: WILEY.
Harvey, E., Langton, D., Upham, J., Hew, M., Rimmer, J., Chung, L., Katelaris, C., James, A. and Gibson, P. (2018). SEVERE EOSINOPHILIC AASTHMA IN AUSTRALIA: THE AUSTRALIAN MEPOLIZUMAB REGISTRY. HOBOKEN: WILEY.
Scott, H., Wood, L. and Upham, J. (2018). A single bout of moderate-intensity exercise reduces eosinophilic airway inflammation in inactive adults with asthma, while vigorous-intensity exercise has no effect. ANZSRS/TSANZ Annual Scientific Meeting, Adelaide, Australia, 23-27 March 2018. Richmond, VIC, Australia: Wiley-Blackwell.
Ruffles, T., Marchant, J., Buntain, H., Mastera,, Upham, J., Yerkovich, S., Gibson, P., Baines, K., Simpson, J., Pizzutto, S., Hodge, G., Hodge, S. and Chang, A. (2018). Protracted bacterial bronchitis (PBB)-long-term outcomes at five years: a cohort study. 55th Annual Scientific Meeting of the Cardiac Society of Aust and NZ Annual Scientific Meeting, Adelaide, Australia, 23-27 March 2018. Richmond, VIC, Australia: Wiley-Blackwell.
Upham, J. W., Jurak, L. and Xi, Y. (2018). Differential effects of IL-33 on anti-viral immune responses in asthmatic and healthy individuals. International Conference of the American Thoracic Society, San Diego, CA, United States, 18-23 May, 2018. New York, NY, United States: American Thoracic Society.
Murray, L. M., Ferreira, M. A. and Upham, J. W. (2018). The impact of TLR7 and TLR8 gene variations on antiviral immunity and asthma. Congress of the European Academy of Allergy and Clinical Immunology (EAACI), Munich, Germany, 26-30 May 2018 . Chichester, West Sussex, United Kingdom: Wiley-Blackwell.
Upham, J., Jurak, L. and Xi, Y. (2018). IL-33 and rhinovirus effects on IL-33 receptor expression in asthma. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, ,, Adelaide, Australia, 23–27 March 2018. Hoboken, NJ United States: Wiley.
Simpson, Jodie, Powell, Heather, Pabreja, Kavita, Yang, Ian, Upham, John, Reynolds, Paul, Hodge, Sandra, James, Alan, Jenkins, Christine, Peters, Matthew, Marks, Guy, Gibson, Peter and Baraket, Melissa (2017). Sputum IL-1 beta is reduced with Azithromycin add-on therapy in patients with poorly controlled asthma. European-Respiratory-Society (ERS) International Congress, Milan Italy, Sep 09-13, 2017. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/1393003.congress-2017.PA4029
Powell, Heather, Simpson, Jodie L., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B. and Gibson, Peter G. (2017). An Analysis of the Effect of Azithromycin in Persistent Asthma, Based On Pre-Specified Asthma Phenotypes. HOBOKEN: WILEY.
Upham, J. W., Murray, L., Xi, Y., Revez, J. and Ferreira, M. (2017). Determinants Of Rhinovirus And Nucleic Acid Induced Cytokine Production In A Large Group Of Healthy And Asthmatic Individuals. International Conference of the American-Thoracic-Society (ATS), Washington Afghanistan, 19-24 May 2017. New York, NY United States: American Thoracic Society.
Gibson, P. G., Yang, I. A., Upham, J. W., Reynolds, P. N., Hodge, S., James, A. L., Jenkins, C., Peters, M., Marks, G. B., Baraket, M., Simpson, J. L. and Powell, H. (2017). Azithromycin Reduces Exacerbations In Adults With Persistent Symptomatic Eosinophilic Asthma. International Conference of the American-Thoracic-Society (ATS), Washington Dc, May 19-24, 2017. NEW YORK: AMER THORACIC SOC.
Murray, Liisa, Xi, Yang, Revez, Joana A., Ferreira, Manuel A. and Upham, John W. (2017). Determinants of Rhinovirus and Nucleic Acid Induced Cytokine Production in a Large Cohort. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Canberra, Australia, 24–28 March 2017. Richmond, VIC Australia: Wiley.
Upham, John, Jurak, Lisa and Xi, Yang (2017). IL-33 augments rhinovirus-induced type 2 immune responses in asthma via selective upregulation of one chain of the IL-33 receptor. ERS International Congress 2017, Milan, Italy, 9-13 September 2017. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/1393003.congress-2017.pa567
Gibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather and Simpson, Jodie L. (2017). Azithromycin Reduces Exacerbations in Adults with Persistent Symptomatic Eosinophilic Asthma. HOBOKEN: WILEY.
Davies, J., Timbrell, V, Reibelt, L., Simmonds, C., Solley, G., Smith, W., Mclean-Tooke, A., van Nunen, S., Smith, P., Upham, J. and Langguth, D. (2016). Regional variation in allergic sensitivity to subtropical and temperate grass pollen allergens; outcomes of the multicentre cross-sectional Grass Pollen Allergy Survey (GPAS). International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.
Murray, L., Ferreira, M. and Upham, J. (2016). Plasmacytoid dendritic cell numbers predict individual interferon-alpha production more accurately than TLR7 expression. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.
Lynch, J. P., Werder, R. B., Simpson, J., Upham, J. W. and Phipps, S. (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening anti-viral immunity. Meeting of the European-Academy-of-Allergy-and-Clinical-Immunology, Vienna Austria, Jun 11-15, 2016. HOBOKEN: WILEY-BLACKWELL.
Simpson, J., Loh, Z., Zhang, , Spann, K., Upham, J. and Phipps, S. (2016). Absence of interferon-beta promotor stimulator-1 (IPS1) induces bronchiolitis and asthma-like pathology in response to pneumoviral infection. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.
Simpson, J., Powell, H., Yang, I, Upham, J., Reynolds, P., Hodge, S., James, A., Jenkins, C., Peters, M., Marks, G., Baraket, M. and Gibson, P. (2016). Sputum Inflammatory Phenotypes in Symptomatic Asthma Around Australia. HOBOKEN: WILEY-BLACKWELL.
Simpson, J., Loh, Z., Zhang, V, Spann, K., Upham, J. and Phipps, S. (2016). ABSENCE OF INTERFERON-beta PROMOTOR STIMULATOR-1 (IPS1) INDUCES BRONCHIOLITIS AND AN ASTHMA-LIKE PATHOLOGY IN RESPONSE TO PNEUMOVIRAL INFECTION. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.
Harvey, E., Gibson, P., Bardin, P., Peters, M., Reynolds, P., Upham, J., Reddel, H., Kritikos, , Katelaris, C., Cochrane, B., Thien, F., Azad, A., Hew, M., Yang, , Brockway, B., Garrett, J., Yap, E., Jones, S., Southcott, A., Jayaram, L., Gillman A, E. G., Uddin, N., Rimmer, J., Katsoulotos, G., Smith, , Jenkins, C., Wark, P. and Mcdonald, (2016). CHARACTERISATION OF SEVERE ASTHMA PHENOTYPES VIA A SEVERE ASTHMA REGISTRY: THE SEVERE ASTHMA WEB-BASED DATABASE. HOBOKEN: WILEY-BLACKWELL.
Leong, L., Rogers, G., Gibson, P., Yang, , Reynolds, P., Hodge, S., James, A., Upham, J., Jenkins, C., Peters, M., Marks, G., Baraket, M. and Simpson, J. (2016). THE LUNG MICROBIOTA IN STABLE ADULT ASTHMA DIFFERS ACCORDING TO INFLAMMATORY PHENOTYPE. HOBOKEN: WILEY-BLACKWELL.
Gibson, P., Reddel, H., Jenkins, C., Marks, G., Upham, J., Gillman, A., Thien, F., Sutherland, M., Rimmer, J., Katsoulotos, G., Cook, M., Yang, , Katelaris, C., Bowler, S., Langton, D., Robinson, P., Wright, C., Yozghatlian, , Burgess, S., Mcdonald, , Sivakumaran, P., Jaffe, A., Bowden, J., Guo, M., Wark, P., Yan, K. Y., Kritikos, V., Peters, M., Baraket, M. ... Bint, M. (2016). EFFECTIVENESS AND RESPONSE PREDICTORS OF OMALIZUMAB IN A SEVERE ALLERGIC ASTHMA POPULATION WITH A HIGH PREVALENCE OF COMORBIDITIES: THE AUSTRALIAN XOLAIR REGISTRY. HOBOKEN: WILEY-BLACKWELL.
Werder, R., Zhang, V, Lynch, J., Spann, K., Upham, J. and Phipps, S. (2016). Anti-Il-33 Partly Ameliorates a Rhinovirus-Induced Exacerbation of Asthma in Predisposed Mice. HOBOKEN: WILEY-BLACKWELL.
Harvey, E., Gibson, P., Bardin, P., Peters, M., Reynolds, P., Upham, J., Reddel, H., Kritikos, , Katelaris, C., Cochrane, B., Thien, F., Azad, A., Hew, M., Yang, , Brockway, B., Garrett, J., Yap, E., Jones, S., Southcott, A., Jayaram, L., Gillman A, E. G., Uddin, N., Rimmer, J., Katsoulotos, G., Smith, , Jenkins, C., Wark, P. and Mcdonald, (2016). SEVERE ASTHMA IS ASSOCIATED WITH WORK PRODUCTIVITY LOSS, ACTIVITY IMPAIRMENT AND REDUCED QUALITY OF LIFE. HOBOKEN: WILEY-BLACKWELL.
Scott, H., Gibson, P., Grag, M., Upham, J. and Wood, L. (2016). SEX HORMONES AND SYSTEMIC CYTOKINES ARE INDEPENDENT MODULATORS OF THE OBESE-ASTHMA PHENOTYPE. HOBOKEN: WILEY-BLACKWELL.
Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., Macdonald, , Guo, M., Reddel, H., Jenkins, C., Marks, G., Upham, J., Thien, F., Rimmer, J., Katsoulotos, G., Cook, M., Yang, , Katelaris, C., Bowler, S., Langton, D., Gibson, P., Robinson, P., Wright, C., Bint, M., Yozghatlian, V., Burgess, S., Sivakumaran, P., Jaffe, A., Yan, K. Y., Kritikos, V. ... Aminazad, A. (2016). CLINICAL EFFECTIVENESS OF OMALIZUMAB IN SEVERE ALLERGIC ASTHMA ABOVE THE STANDARD DOSING RANGE: THE AUSTRALIAN XOLAIR REGISTRY. HOBOKEN: WILEY-BLACKWELL.
Upham, John, Xi, Camilla, Pena, Olga and Bosco, Anthony (2016). LSC Abstract - Punching above their weight: Plasmacytoid dendritic cells play a critical role in regulating rhinovirus induced gene expression pathways. ERS International Congress 2016, London, United Kingdom, 3-7 September, 2016. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2016.PP236
Upham, J., Xi, Y., Pena, O. and Bosco, A. (2016). Plasmacytoid Dendritic Cells Play a Critical Role in Regulating Rhinovirus Induced Gene Expression Pathways. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. HOBOKEN: European Respiratory Society. doi: 10.1183/13993003.congress-2016.pp236
Lynch, J., Rogers, M., Lane, K., Werder, R., Loh, Z., Diener, K., Hayball, J., Hill, G., Haque, A., Spann, K., Mazzone, S., Upham, J. and Phipps, S. (2016). Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/resp.12755_3
Werder, R., Hodge, N., Lynch, J., Simpson, J., Zhang, V, Forbes-Blom, E., Upham, J., Spann, K., Everard, M. and Phipps, S. (2016). Prostaglandin D2 contributes to severity of pneumoviral bronchiolitis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
Upham, J., Landgraf, M., Xi, Y. and Carroll, M. (2016). Il-33 Augments Rhinovirus-Induced Type 2 Immune Responses in Subjects with Asthma, But Not in Healthy Individuals. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. HOBOKEN: WILEY-BLACKWELL.
Rogers, G. B., Leong, L. E., Gibson, P. G., Yang, I. A., Hodge, S. J., Reynolds, P. N., James, A. L., Upham, J. W., Jenkins, C., Peters, M., Baraket, M. and Simpsons, J. L. (2016). The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy. International Conference of the American-Thoracic-Society (ATS), San Francisco, Ca, United States, May 13-18, 2016. NEW YORK: AMER THORACIC SOC.
Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., McDonald, V., Guo, M., Reddel, H., Jenkins, C., Marks, G., Upham, J., Thien, F., Rimmer, J., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Gibson, P. G., Robinson, P. D., Wright, C., Bint, M., Yozghatlian, V., Burgess, S., Sivakumaran, P., Jaffe, A., Yan, K., Peters, M. ... Aminazad, A. (2016). Clinical Effectiveness Of Omalizumab In Severe Allergic Asthma Above The Recommended Dosing Range: The Australian Xolair Registry. International Conference of the American-Thoracic-Society (ATS), San Francisco Ca, May 13-18, 2016. NEW YORK: AMER THORACIC SOC.
Xi, Yang , Anthony, Bosco and Upham, John (2016). Critical Role of pDC in regulating gene expression and innate immune responses to human rhinovirus. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016.
Werder, R., Lynch, J., Simpson, J., Loh, Z., Zhang, V., Spann, K., Sly, P., Mazzone, S., Upham, J. and Phipps, S. (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening type I and III interferon production. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
Upham, J., Xi, C., Pena, O. and Bosco, A. (2016). Plasmacytoid Dendritic Cells Play A Critical Role In Regulating Gene Expression Patterns Induced By Human Rhinoviruses. International Conference of the American-Thoracic-Society (ATS), San Francisco Ca United States, 13-18 May 2016. New York, NY United States: American Thoracic Society.
Xi, Y., Bosco, A. and Upham, J. W. (2016). Critical role of pDC in regulating gene expression and innate immune responses to human rhinovirus. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. Weinheim, Germany: Wiley.
Werder, R. B., Lynch, J., Simpson, J., Loh, Z., Zhang, V., Spann, K., Sly, P., Mazzone, S., Upham, J. and Phipps, S. (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening Type I and III interferon production. 4th Annual Meeting of The International Cytokine and Interferon Society (ICIS), San Francisco, CA, United States, October 16 - 19 2016. London, United Kingdom: Academic Press.
Chen, Alice, Pena, Olga, Nel, Hanno, Pizzuto, Susan, Petsky, Helen, Gardiner, Samantha, Yerkovich, Stephanie, Baines, Katie, Gibson, Peter, Hodge, Greg, Hodge, Sandra, Buntain, Helen, Chang, Anne and Upham, John (2016). Alveolar macrophage in protracted bacterial bronchitis. ERS International Congress 2016, London, United Kingdom, 2016. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2016.PA3977
Simpson, J., Yang, I. A., Upham, J. W., Reynolds, P. N., Hodge, S., James, A. L., Jenkins, C., Peters, M. J., Jia, G., Holweg, C. T. J. and Gibson, P. G. (2015). Sputum and Serum Periostin Levels Are Associated With, But Do Not Predict Sputum Eosinophil Proportion in Severe Asthma. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland Australia, Mar 27-Apr 01, 2015. HOBOKEN: WILEY-BLACKWELL.
Upham, J., Chen, A., Carroll, M., Petsky, H., Pizzutto, S., Yerkovich, S., Baines, K., Simpson, J., Gibson, P., Hodge, G., Hodge, S. and Chang, A. (2015). Immune Responses to Nontypeable Haemophilus Influenzae in Protracted Bacterial Bronchitis. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland Australia, Mar 27-Apr 01, 2015. HOBOKEN: WILEY-BLACKWELL.
Werder, R., Lynch, J., Simpson, J., Loh, Z., Zhang, , Spann, K., Sly, P., Mazzone, S., Upham, J. and Phipps, S. (2015). AEROALLERGEN-INDUCED IL-33 PREDISPOSES TO RESPIRATORY VIRUS-INDUCED ASTHMA BY DAMPENING TYPE I AND III INTERFERON PRODUCTION. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland Australia, Mar 27-Apr 01, 2015. HOBOKEN: WILEY-BLACKWELL.
Lynch, J., Rogers, M., Lane, K., Werder, R., Loh, Z., Diener, K., Hayball, J., Hill, G., Haque, A., Spann, K., Mazzone, S., Upham, J. and Phipps, S. (2015). PDC EXPANSION OF NTREG LIMITS SEVERE PNEUMOVIRUS-INDUCED BRONCHIOLITIS AND ATTENUATES THE ONSET OF VIRUS-PROVOKED ASTHMA. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland Australia, Mar 27-Apr 01, 2015. HOBOKEN: WILEY-BLACKWELL.
Davies, Janet M., Solley, Graham O., Smith, William B., McLean-Tooke, Andrew, van Nunen, Sheryl A., Smith, Peter Kenneth, Timbrell, Victoria L., Upham, John W. and Langguth, Daman (2015). A Multicentre Cross-Sectional Survey of Allergic Sensitisation to Subtropical and Temperate Grass Pollens. Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Houston Tx, Feb 20-24, 2015. NEW YORK: MOSBY-ELSEVIER. doi: 10.1016/j.jaci.2014.12.1396
Simpson, J., Yang, I. A., Upham, J. W., Reynolds, P. N., Hodge, S., James, A. L., Jenkins, C. R., Peters, M. J., Jia, G., Holweg, C. T. and Gibson, P. G. (2015). Sputum And Serum Periostin Levels Are Associated With, But Do Not Predict Sputum Eosinophil Proportion In Severe Asthma. International Conference of the American-Thoracic-Society (ATS), Denver Co, May 15-20, 2015. NEW YORK: AMER THORACIC SOC.
Wurzel, D., Marchant, J., Yerkovich, S., Upham, J., Petsky, H. and Chang, A. (2015). Protracted Bacterial Bronchitis (PBB) in children: natural history and risk factors for bronchiectasis. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, QLD, Australia, 27 March – 1 April 2015. doi: 10.1111/resp.12494
Scott, H., Latham, J., Callister, R., Pretto, J., Saltos, N., Upham, J. and Wood, L. (2015). A Single Bout of Exercise Is Associated with a Transient Reduction to Exhaled Nitric Oxide in Physically Inactive Adults with Asthma. The Annual Scientific Meeting for Leaders in Lung Health and Respiratory Science (TSANZSRS), Gold Coast, QLD Australia, 27 March - 1 April 2015. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12495_2
Upham, J. W., Chang, A., Pizzutto, S., Carroll, M., Gibson, P., Simpson, J., Baines, K. J., Petsky, H., Yerkovich, S. and Chen, A. (2015). Immune Responses To Non-Typeable Haemophilus Influenzae In Protracted Bacterial Bronchitis. International Conference of the American-Thoracic-Society (ATS), Denver Co, May 15-20, 2015. NEW YORK: AMER THORACIC SOC.
Loh, Z., Ullah, A., Zhang, V., Lynch, J., Werder, R., Simpson, J., Upham, J., Mazzone, S., Spann, K. and Phipps, S. (2015). Interferon Regulatory Factor 7 Protects Against Pneumovirus-Induced Airway Smooth Muscle Growth in Early Life. TSANZ 2015 Annual Scientific Meeting, Gold Coast, QLD Australia, 28 March - 1 April 2015. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12494_7
Upham, John, Landgraf, Megan and Xi, Camilla (2015). Interleukin-33 augments rhinovirus-induced type 2 immune responses in people with asthma, but not in healthy donors. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2015.pa4369
Lynch, J. P., Werder, R. B., Rogers, M. J., Lane, K., Loh, Z., Simpson, J., Diener, K., Hayball, J., Zhang, P., Swiecki, M., Colonna, M., Haque, A., Spann, K., Mazzone, S. B., Hill, G. R., Upham, J. W. and Phipps, S. (2014). pDC expansion of nTreg limits severe Pneumovirus-induced bronchiolitis and attenuates the onset of virus-provoked asthma. Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland Australia, Mar 27-Apr 01, 2015. HOBOKEN: WILEY-BLACKWELL.
Hodge, Sandra, Hodge, Greg, Simpson, Jodie L., Yang, Ian, Upham, John, James, Alan, Gibson, Peter G. and Reynolds, Paul N. (2014). Blood cytotoxic/ pro -inflammatory mediators in severe asthma. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
Pretto, Jeffrey, Eckert, Brenton, Simpson, Jodie, Powell, Heather, Upham, John and Gibson, Peter (2014). Inter-instrument variability in exhaled nitric oxide measurement and implications on test interpretation. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
Sutherland, Michael, Gibson, Peter, Thien, Frank, Peters, Matthew, Upham, John, Reddel, Helen, Marks, Guy, Katelaris, Connie and Gilman, Andrew (2014). SEVERE REFRACTORY ALLERGIC ASTHMA IN AUSTRALIA: THE AUSTRALIAN XOLAIR REGISTRY (AXR). HOBOKEN: WILEY-BLACKWELL.
Timbrell, V, Riebelt, L., Simmonds, C., Butler, C., Upham, J., Smith, P., van Nunen, S., Smith, W., McLean-Tooke, A., Solley, G., Kober, A., Langguth, D. and Davies, J. M. (2014). An immunodiagnostic assay for quantitation of specific IgE to the major pollen allergen component, Pas n 1, of the subtropical Bahia grass. European-Academy-of-Allergy-and-Clinical-Immunology Congress, Copenhagen Denmark, Jun 07-11, 2014. HOBOKEN: WILEY-BLACKWELL.
Upham, John, Pizzutto, Susan, Yerkovich, Stephanie, Thomas, Wayne, Hales, Belinda and Chang, Anne (2014). Late-breaking abstract: Improving cell mediated immunity to non-typeable haemophilus influenzae in children with chronic suppurative lung disease. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
Eckert, B., Simpson, J., Powell, H., Pretto, J., Upham, J. and Gibson, P. (2014). EXHALED NITRIC OXIDE MEASUREMENT: INTER-INSTRUMENT VARIABILITY AND IMPLICATIONS ON TESTS INTERPRETATION. HOBOKEN: WILEY-BLACKWELL.
Hodge, S., Hodge, G., Pizzutto, S., Petsky, H., Gibson, P., Chang, A. and Upham, J. (2014). Reduced Macrophage Phagocytic Host Response to Nthi in Children with Bronchiectasis. HOBOKEN: WILEY-LISS.
Wong, M., Upham, J. and Murphy, M. (2014). Clinical Factors Associated with Outcome in Patients Admitted to a Respiratory High Dependency Unit with Hypoxaemic Respiratory Failure. HOBOKEN: WILEY-BLACKWELL.
Guo, M., Gibson, P., Thien, F., Peters, M., Sutherland, M., Upham, J., Reddel, H., Marks, G., Katelaris, C., Gilman, A., Rimmer, J., Yang, , Bowden, J., Robinson, P. and Bowler, S. (2014). SEVERE REFRACTORY ALLERGIC ASTHMA IN AUSTRALIA: THE AUSTRALIAN XOLAIR REGISTRY (AXR). HOBOKEN: WILEY-BLACKWELL.
Simpson, J., Gao, P., Baines, K., Yang, I, Reynolds, P., Hodge, S., James, A., Upham, J., Jenkins, C., Peters, M. and Gibson, P. (2014). Galectin 3 and Galectin 3 Binding Protein in Asthma Inflammatory Subtypes. HOBOKEN: WILEY-BLACKWELL.
Eckert, B., Simpson, J., Powell, H., Pretto, J., Upham, J. and Gibson, P. (2014). EXHALED NITRIC OXIDE MEASUREMENT: INTER-INSTRUMENT VARIABILITY AND IMPLICATIONS ON TEST INTERPRETATION. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/resp.12262_16
Upham, John W., Carroll, Melanie, Gibson, Peter, Yang, Ian A. and Simpson, Jodie (2014). Anti-Viral Innate Immunity Varies Across Different Asthma Inflammatory Phenotypes. Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), San Diego Ca, Feb 28-Mar 04, 2014. NEW YORK: MOSBY-ELSEVIER. doi: 10.1016/j.jaci.2013.12.515
Baines, K., Upham, J., Yerkovich, S., Chang, A., Marchant, J., Carroll, M., Simpson, J. and Gibson, P. (2014). Interleukin-1B Is Related to Clinical Outcomes in Protracted Bacterial Bronchitis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2014 Annual Scientific Meetings, Adelaide, SA Australia, 4‐9 April 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
Gupta, Deepali, Upham, John, Winckel, Karl, Burrows, Judith and Ross, Judy (2014). Utilisation of nicotine replacement therapy (NRT) with a hospital pharmacist initiated smoking-cessation intervention. Medicines Management 2014: 40th SHPA Conference, Darwin, Australia, 11-14 September 2014. Barton, ACT, Australia: Kaigi Conferencing and Events.
Gupta, D., Upham, J., Winckel, K., Burrows, J. and Ross, J. (2014). Utilisation of nicotine replacement therapy with hospital pharmacist initiated smoking cessation intervention. Metro South Heath: Allied Health Showcase 2014, Annerley, QLD, Australia, 17 October, 2014.
Werder, Rhiannon B., Lynch, Jason P., Simpson, Jennifer, Loh, Ken, Zhang, Vivian, Spann, Kirsten, Sly, Peter D., Mazzone, Stuart, Upham, John W. and Phipps, Simon (2014). Critical role for IL-33 in the onset and progression of experimental asthma induced by concomitant virus infection and allergen exposure. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne, VIC, Australia, October 26 - 29, 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.203
Lynch, J., Werder, R. B., Simpson, J., Loh, Z., Zhang, V., Sly, P. D., Mazzone, S., Upham, J. W. and Phipps, S. (2014). Anti-IL-33 ameliorates asthma onset and progression in response to virus and allergen co-exposure. Abstracts of the British Society for Immunology Annual Congress, Brighton, United Kingdom, 1–4 December 2014. Chichester, West Sussex United Kingdom: Wiley-Blackwell Publishing.
Hodge, G., Upham, J., Chang, A., Gibson, P., Pizzutto, S., Petsky, H. and Hodge, S. (2014). Increased Peripheral Blood Pro-Inflammatory/cytotoxic T and Nkt-Like Cells in Indigenous Children with Bronchiectasis. HOBOKEN: WILEY-BLACKWELL.
Teoh, L., Van Asperen, P., Acworth, J., Hurwitz, M., Upham, J., Wang, C., Mackay, I, Sloots, T., Neeman, T. and Chang, A. (2014). Recovery From Acute Asthma Exacerbations in Children: Influence of Viruses, Eczema and Atopy. Annual Scientific Meeting of the Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science 2014, Adelaide, SA Australia, 4-9 April 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12263_4
Fanning, Michael, Lehman, Margot, Mai, Tao, Horwood, Keith, Murphy, Michelle, Mccafferey, Elizabeth, Jovanovic, Lidija and Upham, John (2013). DETECTION OF CIRCULATING TUMOUR CELLS IN ADVANCED NON-SMALL CELL LUNG CANCER. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
Pizzutto, Susan, Yerkovich, Stephanie, Hales, Belinda, Thomas, Wayne, Upham, John and Chang, Anne (2013). Children with chronic suppurative lung disease have a Th2 polarised immune response to H. influenzae. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD.
Collins, T., Anderson, P., Upham, J. and Bowler, S. D. (2013). AN AUDIT OF PEOPLE PRESENTING WITH ACUTE SEVERE ASTHMA: CHRONIC POORLY MANAGED ASTHMA IS COMMON. HOBOKEN: WILEY-BLACKWELL.
Pizzutto, S., Yerkovich, S., Hales, B., Thomas, W., Upham, J. and Chang, A. (2013). H. influenzae-specific antibody responses in children with chronic suppurative lung disease. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, 22-27 March 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/resp.12046
Powell, H., Garside, C. G., Simpson, J. L., Yang, I. A., Reynolds, P. N., Hodge, S. J., James, A. L., Upham, J., Jenkins, C. R., Peters, M. J. and Gibson, P. G. (2013). Characteristics of Uncontrolled Asthma in Australia. 2013 Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science, Darwin, NT Australia, 22 - 27 March 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12046
Simpson, J. L., Yang, I. A., Reynolds, P. N., Hodge, S. J., James, A. L., Upham, J., Jenkins, C., Peters, M. and Gibson, P. G. (2013). Alternatives to Induced Sputum for Identifying Patients with Eosinophilic Asthma. 2013 Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science, Darwin, NT Australia, 22 - 27 March 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12046
Wurzel, D. F., Marchant, J. M., Mackay, I. M., Wang, C. Y., Sloots, T., Upham, J. W., Yerkovich, S., Masters, B. I. and Chang, A. B. (2013). Further description of protracted bacterial bronchitis (PBB) in children. American Thoracic Society 2013 International Conference, Philadelphia, PA, USA, 17-22 May. New York, NY, United States: American Thoracic Society.
Towers, M. A., Collins, T., Green, M. F., Oakland, N. C. and Upham, J. W. (2013). A Nurse-Led Omalizumab Clinic: the Princess Alexandra Hospital Experience. 2013 Annual Scientific Meetings of The Thoracic Society of Australia and New Zealand and the Australian and New Zealand Society of Respiratory Science, Darwin, NT Australia, 22 - 27 March 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12046
Wurzel, D. F., Marchant, J. M., Mackay, I. M., Wang, C. Y. T., Sloots, T., Upham, J., Yerkovich, S., Clark, J., Masters, I. B. and Chang, A. B. (2013). Protracted bacterial bronchitis in children: results of a large prospective cohort study. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, 22-27 March 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/resp.12046
Wurzel, D. F., Marchant, J. M., Upham, J., Yerkovich, S., Masters, I. B., Clark, J. and Chang, A. B. (2013). Wet cough in children: infective and inflammatory characteristics in broncho-alveolar lavage fluid. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, 22-27 March 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/resp.12045
Wurzel, D. F., Marchant, J., Mackay, I. M., Wang, C. Y., Sloots, T. P., Upham, J. W., Yerkovich, S., Anderson-James, S., Baker, P. and Chang, A. B. (2013). Nasopharyngeal Aspirate (npa): is the Ideal viral sampling method in children with chronic respiratory symptoms. ATS 2013 International Conference, Philadelphia, PA, United States, 17-22 May 2013. New York, NY, United States: American Thoracic Society.
Upham, J. W., Carroll, M. and White, O. (2013). Human Rhinovirus Enhances Expression Of Co-Inhibitory Molecules On Antigen Presenting Cells. NEW YORK: AMER THORACIC SOC.
Pizzutto, S. J., Yerkovich, S. T., Upham, J. W. and Chang, A. B. (2012). Adaptive Immunity to Non-Typeable H. Influenzae in Children with Non-Cf Bronchiectasis. MALDEN: WILEY-BLACKWELL.
Wurzel, D., Marchant, J. M., Masters, I. Brent, Yerkovich, S., Upham, J. and Chang, A. B. (2012). Cochrane systematic review - short courses of antibiotics for children and adults with bronchiectasis. Thoracic Society of Australia and New Zealand Annual Scientific Meeting (TSANZ), Canberra, ACT, Australia, 30 March - 4 April 2012. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02143.x
Wurzel, D. F., Marchant, J. M., Masters, I. B., Yerkovich, S. T., Upham, J. W. and Chang, A. B. (2012). Wet cough in children: infective and inflammatory characteristics in broncho-alveolar lavage fluid. 17th Congress of the Asian Pacific Society of Respirology, Hong Kong, Hong Kong, 14-16 December 2012. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02297.x
Garside, C. G., Simpson, J. L., Yang, I. A., Reynolds, P. N., Hodge, S. J., James, A. L., Upham, J., Gibson, P. G. and Amazes Study Research Group (2012). Inflammatory subtypes of uncontrolled asthma in Australia. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra, ACT, 30 March - 4 April 2012. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02142.x
Upham, J. W., Carroll, M. L., Phipps, S., Burel, J. G. and Pritchard, A. L. (2012). Innate interferons and plasmacytoid dendritic cells constrain T(h)2 cytokine responses to rhinovirus: A regulatory mechanism with relevance to asthma. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra ACT, Australia, 30 March-4 April 2012. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02143.x
Upham, J. W., Nath, K., Pritchard, A. L., Towers, M., Looke, D., Davies, J. E. and Burel, J. G. (2012). Impaired immune response to influenza vaccination in chronic obstructive pulmonary disease. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra, ACT, 30 March - 4 April 2012. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02142.x
Upham, John W., Carroll, Melanie L., Burel, Julie G. and Pritchard, Antonia L. (2012). Innate interferons and plasmacytoid dendritic cells constrain Th2 cytokine responses to rhinoviruses: A regulatory mechanism with relevance to asthma. Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Orlando Fl, 2-6 March March 2012. Philadelphia, PA, United States: Mosby. doi: 10.1016/j.jaci.2011.12.367
Upham, J. W., Carroll, M. L., Burel, J. G., White, O. J. and Pritchard, A. L. (2012). Asthma is associated with multiple deficiencies in anti-viral type I interferon signalling pathways. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2012 Annual Scientific Meetings, Canberra, ACT, Australia, 30 March-4 April 2012. Richmond, VIC, United Kingdom: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1843.2012.02142.x
Davies, J., Li, H., Towers, M., Green, M. and Upham, J. (2011). Allergy to subtropical grass pollens compared with temperate grass pollen in patients with allergic rhinitis from a subtropical region. 30th Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Istanbul Turkey, Jun 11-15, 2011. HOBOKEN: WILEY-BLACKWELL.
Upham, J. W., Carroll, M. L., Li, H. and Davies, J. M. (2011). Effects Of Budesonide & Formoterol On Innate Anti-Viral Immune Responses In Vitro. NEW YORK: AMER THORACIC SOC.
Pritchard, Antonia L., Carroll, Melanie L., Burel, Julie and Upham, John W. (2011). Type I interferons and plasmacytoid dendritic cells selectively constrain T(h)2 cytokine responses to rhinoviruses. 22nd Australasian Society of Clinical Immunology and Allergy (ASCIA) Annual Scientific Meeting, Darling Harbour, NSW, Australia, 7-9 September 2011. Richmond, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1445-5994.2011.02570.x
Pizzutto, S. J., Grimwood, Keith, Bauert, P., Schultz, K. I., Yerkovich, Stephanie, Upham, John and Chang, Anne B. (2011). Bronchososcopy with lavage contributes to the clinical management of children with non-CF bronchiectasis. Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Perth, Australia, 2-6 April 2011.
Nath, Karthik, Burel, Julie, Pritchard, Antonia L., Towers, Michelle, Looke, David, Davies, Janet E. and Upham, John W. (2011). Impaired immune response to influenza vaccination in chronic obstructive pulmonary disease. 22nd Australasian Society of Clinical Immunology and Allergy (ASCIA) Annual Scientific Meeting, Darling Harbour, NSW, Australia, 7-9 September 2011. Richmond, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1445-5994.2011.02570.x
Davies, Janet M., Carroll, Melanie L., Li, Hongzhuo, Poh, Alisa M., Kirkegard, Darren, Towers, Michelle and Upham, John W. (2011). Budesonide and formoterol reduce early innate anti-viral immune responses in vitro. Australasian Society of Clinical Immunology and Allergy Annual Scientific Meeting (22nd, ASCIA, 2011), Darling Harbour, NSW, Australia, 7-9 September 2011.
Burel, Julie, Li, Hongzhuo, Wong, Kelly, Towers, Michelle, Upham, John and Davies, Janet (2011). B cell responses to areoalllergens in patient with allergic disease. Australasian Society of Clinical Immunology and Allergy Annual Scientific Meeting (22nd, ASCIA, 2011), Darling Harbour, NSW, Australia, 7-9 September 2011. doi: 10.1111/j.1445-5994.2011.02570.x
Davies, Janet, Li, HonZhuo, Green, Melissa, Towers, Michelle and Upham, John (2010). Grass pollen allergy in Queensland: How important are the subtropical grass pollens for triggering allergic rhinitis and asthma?. 21st Meeting of the Australian Society for Clinical Immunology and Allergy, Gold Coast , QLD, Australia, 1-3 September 2010. Richmond, Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1445-5994.2010.02324.x
Upham, J. W., Yerkovich, S.T., Poh, A., Sly, P. D., Holt, P. G. and Roponen, M. (2009). Reduced expression of anti-viral molecules by blood mononuclear cells is associated With asthma, but not with atopy per se. 65th Annual Meeting of the American Academy of Allergy Asthma and Immunology, Washington, DC, U.S.A., 13-17 March 2009. Milwaukee, WI, U.S.A.: Mosby. doi: 10.1016/j.jaci.2008.12.849
Thompson, B. R., Cowen, G., Friese, M. E. J., Maillet, D., Wang, D., Eckert, B., Upham, J., Harris, B., King, G. G. and Thien, F. (2009). Analysis of Ventilation Heterogeneity (VH) with Hyperpolarized Helium Magnetic Resonance Imaging (HPHeMRI) Following Inhaled Methacholine (MCH) and Mannitol (MNT) Challenges in Asthmatic Subjects. NEW YORK: AMER THORACIC SOC.
Thompson, B. R., Cowin, G., Friese, M. E. J., Maillet, D., Wang, D., Eckert, J., Upham, J., Harris, G., King, G. and Thien, F. (2009). Analysis of ventilation heterogeneity (VH) with hyperpolarized helium magnetic resonance imaging (HPHeMRI) following inhaled methacholine (MCH) and mannitol (MNT) challenges in asthmatic subjects. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2009 Annual Scientific Meetings, Darwin, Australia, 3–8 April 2009. Carlton, Vic., Australia: Blackwell Science. doi: 10.1111/j.1440-1843.2009.01500_3.x
Taylor, R. C., Richmond, P. and Upham, J. W. (2005). Toll-like receptor 2 ligands inhibit Th2 responses to mite allergen. 35th Annual Scientific Meeting of the Australasian Society for Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, Australia, 29 November - 2 December 2005. OXFORD: BLACKWELL PUBLISHING.
Upham, J. W., Rate, A., Kusel, M., Sly, P. D. and Holt, P. G. (2005). Numbers of circulating plasmacytoid and myeloid dendritic cell subsets in infancy are differentially associated with risk for respiratory viral infections and allergic sensitisation. 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA & Immunogenetics Workshop, Melbourne, Australia, 29 November-2 December 2005. OXFORD: BLACKWELL PUBLISHING.
Rate, A., Kicic, A., Stick, S. M. and Upham, J. W. (2005). Airway epithelial cells from healthy children inhibit dendritic cell activation and cytokine synthesis. 35th Annual SCientific Meeting of the Australasian Society for Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, Australia, 29 November -2 December 2005. OXFORD: Wiley.
Yerkovich, ST, Mus, A and Upham, JW (2005). Influence of APC maturity on the expression of allergen specific T cell memory. 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne AUSTRALIA, NOV 29-DEC 02, 2005. OXFORD: BLACKWELL PUBLISHING.
Fogel, MF, Long, JAL, Thompson, PJT and Upham, JWU (2002). The synthetic immune response modifier induces dendritic cells to mature and synthesize cytokines via a pathway distinct from lipopolysaccharide. 21st Congress of the European-Academy-of-Allergology-and-Clinical-Immunology, Naples Italy, Jun 01-05, 2002. COPENHAGEN: BLACKWELL MUNKSGAARD.
Fogel, M., Long, J. A., Thompson, P. J. and Upham, J. W. (2002). The synthetic immune response modifier R-848 induces dendritic cells to mature and synthesize a diverse range of cytokines via a pathway distinct from lipopolysaccharide. Annual Meeting of the American Academy of Allergy, Asthma and Immunology, New York City, NY United States, 1-6 March 2002. Philadelphia, PA, United States: Mosby. doi: 10.1016/S0091-6749(02)81297-0
Denburg, Judah A., Sehmi, Roma and Upham, John (2001). Regulation of IL-5 receptor on eosinophil progenitors in allergic inflammation: role of retinoic acid. 23rd Symposium of the Collegium Internationale Allergologicum (CIA 2000), Hakone, Japan, 18-23 May 2000. Basel, Switzerland: Karger. doi: 10.1159/000053724
Lacosta, S., Sehmi, R., Upham, J., Hayes, L., Tavernier, J. and Denburg, J. A. (2000). Modulation of eosinophil progenitor growth and IL5R alpha expression on CD34+cells by retinoic acid. Annual Meeting of the American Academy of Allergy, Asthma and Immunology, San Diego California USA, 3-8 March 2000. Philadelphia, PA, United States: Mosby. doi: 10.1016/S0091-6749(00)91195-3
Denburg, Judah A., Sehmi, Roma, Upham, John, Wood, Lorna, Gauvreau, Gail and O'Byrne, Paul (1999). Regulation of IL-5 and IL-5 receptor expression in the bone marrow of allergic asthmatics. 22nd Symposium of the Collegium Internationale Allergologicum, Corfu, Greece, 12-16 September 1998. Basel, Switzerland: Karger. doi: 10.1159/000024040
Narita, S, Upham, J, Lundahl, J, Watson, R, Croitru, K and O'Byrne, PM (1999). Circulating T-cells and granulocytes from asthmatics exhibit impaired capacity for intracellular IL-10 production. ST LOUIS: MOSBY-YEAR BOOK INC.
Upham, J. W., Denburg, J. A. and O'Byrne, P. M. (1999). Circulating dendritic cells and asthma: Rapid response to inhaled allergen. -, -, -. New York, NY, United States: American Thoracic Society.
Narita, S., Upham, J., Lundahl, J., Watson, R., Croitru, K. and O'Byrne, P. M. (1999). Intracellular cytokines in T-cells from patients with allergic asthma and the effects of inhaled corticosteroids. -, -, -. New York, NY, United States: American Thoracic Society.
Lundahl, J., Sehmi, R., Hayes, L., Upham, J., Howie, K. and Denburg, J. A. (1998). Induction of eosinophilic differentiation involves selective up-regulation of beta-7 integrin. Unknown, Unknown, Unknown. ST LOUIS: MOSBY-YEAR BOOK INC.
Upham, J. W., Hayes, L. M., Sehmi, R. and Denburg, J. A. (1998). Retinoic acid selectively inhibits IL-5 receptor expression during differentiation of hemopoietic progenitor cells. Annual Meeting of the American Academy of Allergy, Asthma and Immunology, Washington DC, United States, 13-18 March 1998. Philadelphia, PA, United States: Mosby.
Upham, J. W. (1997). T-cell proliferative responses to mite allergens are detectable in most individuals regardless of atopic status and age. Unknown, Unknown, Unknown. Blackwell Publishing. doi: 10.1111/j.1440-1843.1997.tb00069.x
Holt, P. G., Nelson, D. J., McWilliam, A. S., Cooper, D., Strickland, D. and Upham, J. W. (1996). Role of dendritic cells, macrophages, and gamma delta T cells in antigen processing and presentation in the respiratory mucosa. 8th International Congress of Mucosal Immunology, San Diego CA, United States, 4 June 1995. SAN DIEGO: Academic Press. doi: 10.1016/B978-012394330-9/50006-5
Robinson, B. W. S., Manning, L. S., Bowman, R. V., Christmas, T. I., Musk, A. W., Davis, M. R., Bielefeldt-Ohmann, H., Upham, J. and Garlepp, M. J. (1993). The scientific basis for the immunotherapy of human malignant mesothelioma. International Conference on Mesothelial Cell and Mesothelioma: Past, Present and Future, Paris, France, 20 September - 2 October 1991. European Respiratory Society: Lausanne, Switzerland.