Dr Ahmed Mehdi
Research Fellow
The University of Queensland Diamantina Institute
+61 7 344 36947
Publications
Book Chapter
Ali, Rubbiya A., Naqi, Ali, Ali, Sarah, Fatima, Mashal, Ishaq, Musarat and Mehdi, Ahmed M. (2019). Statistical and probabilistic approaches to predict protein abundance. Encyclopedia of Bioinformatics and Computational Biology. (pp. 847-854) edited by Shoba Ranganathan, Michael Gribskov, Kenta Nakai and Christian Schönbach. Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-809633-8.20466-4
Journal Articles
Sadeghirad, Habib, Monkman, James, Mehdi, Ahmed M., Ladwa, Rahul, O’Byrne, Ken, Hughes, Brett G. M. and Kulasinghe, Arutha (2022). Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell Carcinomas. Frontiers in Immunology, 13, 1-11. doi: 10.3389/fimmu.2022.895513
Rødahl, Inga, Gotley, James, Andersen, Stacey B., Yu, Meihua, Mehdi, Ahmed M., Christ, Angelika N., Hamilton-Williams, Emma E., Frazer, Ian H., Lukowski, Samuel W. and Chandra, Janin (2021). Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq. STAR Protocols, 2 (4) 100842, 1-27. doi: 10.1016/j.xpro.2021.100842
Ishaq, Musarat, Bandara, Nadeeka, Morgan, Steven, Nowell, Cameron, Mehdi, Ahmad M., Lyu, Ruqian, McCarthy, Davis, Anderson, Dovile, Creek, Darren J., Achen, Marc G., Shayan, Ramin and Karnezis, Tara (2021). Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema. International Journal of Obesity, 46 (3), 502-514. doi: 10.1038/s41366-021-01002-1
Budhwani, Megha, Turrell, Gavin, Yu, Meihua, Frazer, Ian H., Mehdi, Ahmed M. and Chandra, Janin (2021). Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patients. Frontiers in Molecular Biosciences, 8 622643, 622643. doi: 10.3389/fmolb.2021.622643
Benham, Helen, Chiu, Hedva, Tesiram, Joanne, Mehdi, Ahmed, Landsberg, Peter, Grosman, Sergei, Harrison, Andrew, Nash, Peter, Thomas, Ranjeny, Langbecker, Danette and Van Driel, Mieke (2021). A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectives. International Journal of Rheumatic Diseases, 24 (3), 355-363. doi: 10.1111/1756-185x.14051
Xie, Min, Yunis, Joseph, Yao, Yin, Shi, Jing, Yang, Yang, Zhou, Pengcheng, Liang, Kaili, Wan, Yanmin, Mehdi, Ahmed, Chen, Zhian, Wang, Naiqi, Xu, Shuyun, Zhou, Min, Yu, Muqing, Wang, Ke, Tao, Yu, Zhou, Ying, Li, Xiaochen, Liu, Xiansheng, Yu, Xiao, Wei, Yunbo, Liu, Zheng, Sprent, Jonathan and Yu, Di (2021). High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses. Clinical & Translational Immunology, 10 (2) e1251, e1251. doi: 10.1002/cti2.1251
Koller‐Smith, Louise, Mehdi, Ahmed M., March, Lyn, Tooth, Leigh, Mishra, Gita and Thomas, Ranjeny (2021). Rheumatoid arthritis is a preventable disease: 11 ways to reduce your patients’ risk. Internal Medicine Journal, 52 (5), 711-716. doi: 10.1111/imj.15537
Musthaffa, Yassmin, Hamilton‐Williams, Emma E, Nel, Hendrik J., Bergot, Anne‐Sophie, Mehdi, Ahmed M., Harris, Mark and Thomas, Ranjeny (2021). Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes. Clinical & Translational Immunology, 10 (7) e1315, e1315. doi: 10.1002/cti2.1315
Garcia-Gonzalez, Paulina A., Maggi, Jaxaira, Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Soto, Lilian, Neire, Oscar, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Aravena, Octavio, Carmen Molina, Maria, Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Carlos Aguillon, Juan (2019). Regulation of tolerogenic features on dexamethasone-modulated MPLA-activated dendritic cells by MYC. Frontiers in Immunology, 10 (MAY) 1171, 1171. doi: 10.3389/fimmu.2019.01171
Zahir, Syeda F., Griffin, Alison, Veerman, J. Lennert, Magliano, Dianna J., Shaw, Jonathan E., Cao, Kim-Anh Lê and Mehdi, Ahmed M. (2019). Exploring the association between BMI and mortality in Australian women and men with and without diabetes: the AusDiab study. Diabetologia, 62 (5), 754-758. doi: 10.1007/s00125-019-4830-4
Rehaume, Linda M., Matigian, Nicholas, Mehdi, Ahmed M., Lachner, Nancy, Bowerman, Kate L., Daly, Joshua, Lê Cao, Kim-Anh, Hugenholtz, Philip and Thomas, Ranjeny (2019). IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiota. Annals of the Rheumatic Diseases, 78 (4), 494-503. doi: 10.1136/annrheumdis-2018-214381
Buchanan, Kerry, Mehdi, Ahmed M, Hughes, Ian, Cotterill, Andrew, Le Cao, Kim-Anh, Thomas, Ranjeny and Harris, Mark (2018). An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes. Pediatric Diabetes, 20 (2), 166-171. doi: 10.1111/pedi.12808
Ison, Matthew, Duggan, Emily, Mehdi, Ahmed, Thomas, Ranjeny and Benham, Helen (2018). Treatment delays for patients with new onset rheumatoid arthritis presenting to an Australian early arthritis clinic. Internal Medicine Journal, 48 (12), 1498-1504. doi: 10.1111/imj.13972
O'Sullivan, Brendan J., Yekollu, Suman, Ruscher, Roland, Mehdi, Ahmed M., Maradana, Muralidhara Rao, Chidgey, Ann P. and Thomas, Ranjeny (2018). Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice. Frontiers in Immunology, 9 (MAY) 1092, 1092. doi: 10.3389/fimmu.2018.01092
Mehdi, Ahmed M., Hamilton-Williams, Emma E., Cristino, Alexandre, Ziegler, Anette, Bonifacio, Ezio, Le Cao, Kim-Anh, Harris, Mark and Thomas, Ranjeny (2018). A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes. JCI Insight, 3 (5). doi: 10.1172/jci.insight.98212
Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Larrondo, Milton L., Aravena, Octavio, Molina, Mar-A C., Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2017). Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response. Frontiers in Immunology, 8 (OCT) 1350, 1350. doi: 10.3389/fimmu.2017.01350
Ali, Rubbiya A., Mehdi, Ahmed M., Rothnagel, Rosalba, Hamilton, Nicholas A., Gerle, Christoph, Landsberg, Michael J. and Hankamer, Ben (2017). RAZA: A Rapid 3D z-crossings algorithm to segment electron tomograms and extract organelles and macromolecules. Journal of Structural Biology, 200 (2), 73-86. doi: 10.1016/j.jsb.2017.10.002
Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 (OCT) 458, 458. doi: 10.3389/fimmu.2016.00458
Pang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17
Benham, Helen, Nel, Hendrik J., Law, Soi Cheng, Mehdi, Ahmed M., Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Lee, Bernett T., Ng, Jennifer, Brunck, Marion E. G., Hyde, Claire, Trouw, Leendert A., Dudek, Nadine L., Purcell, Anthony W., O'Sullivan, Brendan J., Connolly, John E., Paul, Sanjoy K., Le Cao, Kim-Anh and Thomas, Ranjeny (2015). Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients. Science Translational Medicine, 7 (290) 290ra87, 290ra87.1-290ra87.11. doi: 10.1126/scitranslmed.aaa9301
Roona, Gergely, Borsos, Mate, Ellis, Jonathan J., Mehdi, Ahmed M., Christie, Mary, Koornyei, Zsuzsanna, Neubrandt, Mate, Tooth, Judit, Bozooky, Zoltan, Buday, Laszlo, Madaraasz, Emilia, Bodaen, Mikael, Kobe, Bostjan and Veertessy, Beata G. (2014). Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation. Cell Cycle, 13 (22), 3551-3564. doi: 10.4161/15384101.2014.960740
Mehdi, Ahmed M., Patrick, Ralph, Bailey, Timothy L. and Boden, Mikael (2014). Predicting the dynamics of protein abundance. Molecular and Cellular Proteomics, 13 (5), 1330-1340. doi: 10.1074/mcp.M113.033076
Mehdi, Ahmed M., Sehgal, Muhammad Shoaib B., Kobe, Bostjan, Bailey, Timothy L. and Boden, Mikael (2013). DLocalMotif: a discriminative approach for discovering local motifs in protein sequences. Bioinformatics, 29 (1), 39-46. doi: 10.1093/bioinformatics/bts654
Marfori, Mary, Mynott, Andrew, Ellis, Jonathan J., Mehdi, Ahmed M., Saunders, Neil F. W., Curmi, Paul M., Forwood, Jade K., Bodén, Mikael and Kobe, Bostjan (2011). Molecular basis for specificity of nuclear import and prediction of nuclear localization. Biochimica et Biophysica Acta (BBA): Molecular Cell Research, 1813 (9), 1562-1577. doi: 10.1016/j.bbamcr.2010.10.013
Mehdi, Ahmed M., Sehgal, Muhammad Shoaib B., Kobe, Bostjan, Bailey, Timothy L. and Boden, Mikael (2011). A probabilistic model of nuclear import of proteins. Bioinformatics, 27 (9) btr121, 1239-1246. doi: 10.1093/bioinformatics/btr121
Mehdi, Ahmed M., Zayegh, Aladin, Begg, Rezaul and Ali, Rubbiya (2010). GK based fuzzy clustering for the diagnosis of cardiac arrhythmia. International Journal of Computational Intelligence and Applications, 9 (2), 105-123. doi: 10.1142/S146902681000280X
Conference Papers
Wehr, Pascale, Nel, Hendrik J., Zhou, Chenhao, Mehdi, Ahmed M., McGuire, Helen, Weedon, Helen, Small, Annabelle, Steptoe, Raymond, Gras, Stephanie, Wechalekar, Mihir D. and Thomas, Ranjeny (2021). Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones. Australian Rheumatology Association 61st Annual Scientific Meeting, Hybrid Meeting, 21–23 May 2021. Richmond, VIC, Australia: Wiley-Blackwell.
Wehr, Pascale, Nel, Hendrik, Zhou, Chenhao, Mehdi, Ahmed, Christ, Angelika, Weedon, Helen, Wechalekar, Mihir and Thomas, Ranjeny (2020). Mapping Oligoclonally Expanded T Cells Within the Peripheral and Synovial Immune Landscape of Untreated ACPA plus Rheumatoid Arthritis Patients at the Single Cell Level. ACR Convergence 2020, Virtual, 5-9 November 2020. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.41538
Bhuyan, Zaied Ahmed, Rahman, M. Arifur, Maradana, Muralidhara, Mehdi, Ahmed, Guggino, Giuliana, Leo, Paul, Rehaume, Linda, Brown, Matthew, Ciccia, Francesco and Thomas, Ranjeny (2018). Intestinal inflammatory regulation in murine and human spondyloarthropathy requires high-affinity T cell receptor-zeta chain-associated protein (ZAP) 70-mediated runt-related transcription factor (Runx) 3 activity. 2018 ACR/ARHP Annual Meeting, Chicago, Illinois, 19-24 October 2018. Hoboken, NJ, United States: John Wiley & Sons.
Law, S. C., Nel, H. J., Scally, S. W., Mehdi, A., Le Cao, K. -A, Rossjohn, J., Reid, H. H., La Gruta, N. L. and Thomas, R. (2016). Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
Law, Soi-Cheng, Nel, Hendrik, Mehdi, Ahmed, Le Cao, Kim-Anh and Thomas, Ranjeny (2014). Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, 14-19 November 2014. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/art.38914
Raza, Muhammad Taskeen, Sheikh, Noor M., Fahiem, Muhammad Abuzar and Mehdi, Ahmed M. (2011). Performance of different approaches for predicting the subcellular locations of proteins: a review. INMIC 2011: 14th IEEE International Multitopic Conference, Karachi, Pakistan, 22-24 December, 2011. Piscataway, NJ, USA: IEEE. doi: 10.1109/INMIC.2011.6151518
Mehdi, Ahmed M., Sehgal, Mohammad Shoabib, Zayegh, Aladin, Begg, Rezaul and Manan, Abdul (2009). K-Means Clustering on 3rd order polynomial based normalization of Acute Myeloid Leukemia (AML) and Acute Lymphocyte Leukemia (ALL). ICEE 2009: 3rd International Conference on Electrical Engineering, Lahore, Pakistan, 9-11 April, 2009. Piscataway, NJ, USA: IEEE. doi: 10.1109/ICEE.2009.5173170
Paracha, Zahir J., Mehdi, Ahmed M. and Kalam, Akhtar (2009). Computational analysis of sag and swell in electrical power distribution network. AUPEC '09 : 19th Australasian Universities Power Engineering Conference : sustainable energy technologies and systems, Adelaide, SA Australia, 27 - 30 September 2009. Piscataway, NJ United States: I E E E.
Thesis
Mehdi, Ahmed Murtaza (2013). Computational models of nucleo-cytoplasmic trafficking by integrating heterogeneous data. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland.
Data Collections
Ahmed Mehdi (2022). Environmental Pathways Database. The University of Queensland. (Dataset) doi: 10.48610/ee3f1f2
Ahmed Mehdi (2022). GSAO - Gene Set Annotation Overlap (Version 0.1.0). The University of Queensland. (Dataset) doi: 10.48610/2c1d352
Ahmed M. Mehdi (2022). NucImport. The University of Queensland. (Dataset) doi: 10.48610/7bfd689
Ahmed M. Mehdi (2022). PredictPA. The University of Queensland. (Dataset) doi: 10.48610/a53d449
Ahmed Mehdi (2021). E.PAGE. The University of Queensland. (Dataset) doi: 10.14264/e63e27d
Preprints
Monkman, James, Kim, Honesty, Mayer, Aaron, Mehdi, Ahmed, Matigian, Nicholas, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Mueller, Scott N., Adams, Mark N., O’Byrne, Ken and Kulasinghe, Arutha (2021). IL-2 stromal signatures dissect immunotherapy response groups in nonsmall cell lung cancer (NSCLC).