Dr Loredana Spoerri
Research Officer
The University of Queensland Diamantina Institute
+61 7 344 37115
Book Chapters
Spoerri, Loredana, Beaumont, Kimberley A., Anfosso, Andrea and Haass, Nikolas K. (2017). Real-time cell cycle imaging in a 3D cell culture model of melanoma. In 3D cell culture: methods and protocols (pp. 401-416) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-7021-6_29
Spoerri, Loredana, Oo, Zay Yar, Larsen, Jill E., Haass, Nikolas K., Gabrielli, Brian and Pavey, Sandra (2015). Cell cycle checkpoint and DNA damage response defects as anticancer targets: from molecular mechanisms to therapeutic opportunities.. Stress response pathways in cancer: from molecular targets to novel therapeutics. (pp. 29-49) edited by Georg T. Wondrak. Dordrecht: Springer Science+Business Media. doi: 10.1007/978-94-017-9421-3_3
Spoerri, Loredana, Barnham, Kevin J ., Multhaup, Gerd and Cappai, Roberto (2013). Role of the amyloid precursor protein and copper in Alzheimer's disease. Brain Diseases and Metalloproteins. (pp. 169-220) edited by David R. Brown. Singapore, Singapore: Pan Stanford Publishing. doi: 10.1201/b12777-7
Journal Articles
Truong, Phan H., Ciccotosto, Giuseppe D., Merson, Tobias D., Spoerri, Loredana, Chuei, Mun Joo, Ayers, Margaret, Xing, Yao Lulu, Emery, Ben and Cappai, Roberto (2019). Amyloid precursor protein and amyloid precursor-like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons. GLIA, 67 (3), 525-538. doi: 10.1002/glia.23561
Oo, Zay Yar, Stevenson, Alexander J., Proctor, Martina A., Daignault, Sheena M., Walpole, Sebastian, Lanagan, Catherine, Chen, James, Skalamera, Dubravka, Spoerri, Loredana, Ainger, Stephen, Sturm, Richard A, Haass, Nikolas K and Gabrielli, Brian (2018). Endogenous replication stress marks melanomas sensitive to CHEK1 inhibitors in vivo. Clinical Cancer Research, 24 (12), 2901-2912. doi: 10.1158/1078-0432.CCR-17-2701
Smith, Michael P., Rowling, Emily J., Miskolczi, Zsofia, Ferguson, Jennifer, Spoerri, Loredana, Haass, Nikolas K., Sloss, Olivia, Mcentegart, Sophie, Arozarena, Imanol, von Kriegsheim, Alex, Rodriguez, Javier, Brunton, Holly, Kmarashev, Jivko, Levesque, Mitchell P., Dummer, Reinhard, Frederick, Dennie T., Andrews, Miles C., Cooper, Zachary A., Flaherty, Keith T., Wargo, Jennifer A. and Wellbrock, Claudia (2017). Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure. EMBO Molecular Medicine, 9 (8), 1011-1029. doi: 10.15252/emmm.201607156
Fane, Mitchell E., Chhabra, Yash, Hollingsworth, David E. J., Simmons, Jacinta L., Spoerri, Loredana, Oh, Tae Gyu, Chauhan, Jagat, Chin, Toby, Harris, Lachlan, Harvey, Tracey J., Muscat, George E. O., Goding, Colin R., Sturm, Richard A., Haass, Nikolas K., Boyle, Glen M., Piper, Michael and Smith, Aaron G. (2017). NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF. EBioMedicine, 16, 63-75. doi: 10.1016/j.ebiom.2017.01.013
Spoerri, Loredana, Brooks, Kelly, Chia, KeeMing, Grossman, Gavriel, Ellis, Jonathan J., Dahmer-Heath, Mareike, Skalamera, Dubravka, Pavey, Sandra, Burmeister, Bryan and Gabrielli, Brian (2016). A novel ATM-dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma. Pigment Cell and Melanoma Research, 29 (3), 329-339. doi: 10.1111/pcmr.12466
Brooks, Kelly, Ranall, Max, Spoerri, Loredana, Stevenson, Alex, Gunasingh, Gency, Pavey, Sandra, Meunier, Fred, Gonda, Thomas J. and Gabrielli, Brian (2014). Decatenation checkpoint defective melanomas are dependent on PI3K for survival. Pigment Cell and Melanoma Research, 27 (5), 813-821. doi: 10.1111/pcmr.12268
Pavey, Sandra, Spoerri, Loredana, Haass, Nikolas K. and Gabrielli, Brian (2013). DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.. Pigment Cell and Melanoma Research, 26 (6), 805-816. doi: 10.1111/pcmr.12136
Brooks, Kelly, Chia, Kee Ming, Spoerri, Loredana, Mukhopadhyay, Pamela, Wigan, Matthew, Stark, Mitchell, Pavey, Sandra and Gabrielli, Brian (2013). Defective decatenation checkpoint function is a common feature of melanoma. Journal of Investigative Dermatology, 134 (1), 150-158. doi: 10.1038/jid.2013.264
Spoerri, Loredana and Gabrielli, Brian (2013). Similar, not the same: diverse roles and regulation of cyclin Es. Cell Cycle, 12 (5), 715-715. doi: 10.4161/cc.23909
Spoerri, Loredana, Vella, Laura J., Pham, Chi L. L., Barnham, Kevin J. and Cappai, Roberto (2012). The amyloid precursor protein copper binding domain histidine residues 149 and 151 mediate APP stability and metabolism. Journal of Biological Chemistry, 287 (32), 26840-26853. doi: 10.1074/jbc.M112.355743
Lei, Peng, Ayton, Scott, Finkelstein, David I., Spoerri, Loredana, Ciccotosto, Giuseppe D., Wright, David K., Wong, Bruce X. W., Adlard, Paul A., Cherny, Robert A., Lam, Linh Q., Roberts, Blaine R., Volitakis, Irene, Egan, Gary F., McLean, Catriona A., Cappai, Roberto, Duce, James A. and Bush, Ashley I. (2012). Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export. Nature Medicine, 18 (2), 291-295. doi: 10.1038/nm.2613
Conference Papers
Spoerri, L., Tonnessen-Murray, Ca, Beaumont, K. A., Hill, D., Jurek, R., Gunasingh, G., Weninger, W. and Haass, N. K. (2020). MITF-mediated changes of tumor architecture, tensile stress and extracellular matrix control intratumor heterogeneity in melanoma. Virtual Conference of the Society for Investigative Dermatology (SID ), Online, 13-16 May 2020. New York, NY, United States: Elsevier.
Daignault, S. M., Spoerri, L., Ju, R. J., Stehbens, S. J., Hill, D. S., Dolcetti, R. and Haass, N. (2019). Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma. In: 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, (E100-E100). 13-16 March, 2019. doi:10.1111/exd.13859
Spoerri, L., Tonnessen, C., Beaumont, K., Hill, D., Jurek, R., Gunasingh, G., Daignault, S. M., Vanwalleghem, G., Weninger, W., Scott, E. and Haass, N. K. (2019). MITF-mediated extracellular matrix changes control intratumour heterogeneity in melanoma. 49th Annual ESDR Meeting, Bordeaux, France, 18-21 September 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.709
Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Smith, A., Scott, E., Schaider, H., Gabrielli, B., Weninger, W. and Haass, N. (2019). Microphthalmia-associated transcription factor regulates dynamic heterogeneity and structural integrity in melanoma. In: 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, (E101-E101). 13-16 March, 2019. doi:10.1111/exd.13859
Daignault, S. M., Ju, R., Spoerri, L., Stehbens, S. J., Hill, D. S., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2019). Bortezomib-induced immunogenic cell death enhances immune response in melanoma. Society for Investigative Dermatology (SID) Meeting, Chicago, Il, United States, 8-11 May, 2019. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2019.03.907
Daignault, S. M., Ju, R. J., Spoerri, L., Stehbens, S. J., Dolcetti, R. and Haass, N. K. (2019). Bortezomib induces immunogenic cell death in melanoma and enhances immune responses in vivo. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.506
Daignault, S. M., Hill, D. S., Spoerri, L., Stehbens, S., Weninger, W., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2018). Targeting cell cycle phase-specific drug sensitivity for melanoma therapy. 45th Annual Meeting of the Arbeitsgemeinscha-Dermatologische-Forschung (ADF), Zurich, Switzerland, 7-10 March 2018. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.
Haass, N. K., Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Daignault, S. M., Ahmed, F., Smith, A. G. and Weninger, W. (2017). Microphthalmia-associated transcription factor regulates dynamic melanoma heterogeneity. 47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Salzburg Austria, Sep 27-30, 2017. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.jid.2017.07.726
Haass, N., Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Daignault, S. M., Gabrielli, B. and Weninger, W. (2017). Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities. Australasian College of Dermatologists 50th Annual Scientific Meeting, International Convention Centre, Sydney, NSW Australia, 6-9 May 2017. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.20_12652
Stehn, J. R., Stevenson, A., Spoerri, L., Daignault, S. M., Gabrielli, B., Eiffe, E., Gunning, P. W. and Haass, N. (2016). Developing a new melanoma drug. HOBOKEN: WILEY-BLACKWELL.
Tonnessen, C. A., Beaumont, K. A., Spoerri, L., Hill, D. S., Jurek, R. J., Daignault, S. M., Ahmed, F., Fane, M., Smith, A., Weninger, W. and Haass, N. K. (2016). MITF regulates cell adhesion and subcompartment-specific distribution of differentially cycling melanoma cells. 43rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung-e-V (ADF), Vienna Austria, Mar 10-12, 2016. HOBOKEN: WILEY-BLACKWELL.
Nierfeld, M., Nascimento, P. R., Baesler, K., Knuever, J., Spoerri, L., Schaider, H., Weninger, W. and Haass, N. K. (2016). Rose Bengal melanoma therapy - phototoxicity versus intrinsic cytotoxicity. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
Ahmed, F., Tonnessen, C., Spoerri, L., Daignault, S., Stark, M., Schaider, H., Hill, M. and Haass, N. (2016). Identification of unique molecular signatures of differentially cycling tumour cell subpopulations in a 3D melanoma model. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12584
Daignault, S. M., Tonnessen, C. A., Ahmed, F., Spoerri, L. and Haass, N. K. (2016). MITF modifies invasion and characteristics of the epithelial to mesenchymal transition in melanoma. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.