Dr Hanno Nel

Adisakwattana, Poom, Saunders, Sean P., Nel, Hendrik J. and Fallon, Padraic G. (2009). Helminth-Derived Immunomodulatory Molecules. In Fallon, P. G. (Ed.), Pathogen-Derived Immunomodulatory Molecules (pp. 95-107) Berlin, Germany: Springer.

Saha, Irene, Jaiswal, Hemant, Mishra, Richa, Nel, (Hanno) Hendrik J., Schreuder, Jaring, Kaushik, Monika, Singh Chauhan, Kuldeep, Singh Rawat, Bhupendra, Thomas, Ranjeny, Naik, Shalin, Kumar, Himanshu and Tailor, Prafullakumar (2020) RelB suppresses type I Interferon signaling in dendritic cells. Cellular Immunology, 349 104043.doi:10.1016/j.cellimm.2020.104043

Garcia-Gonzalez, Paulina A., Maggi, Jaxaira, Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Soto, Lilian, Neire, Oscar, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Aravena, Octavio, Carmen Molina, Maria, Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Carlos Aguillon, Juan (2019) Regulation of tolerogenic features on dexamethasone-modulated MPLA-activated dendritic cells by MYC. Frontiers in Immunology, 10 1171. doi:10.3389/fimmu.2019.01171

Dey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt (2019) A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical, 284 281-288. doi:10.1016/j.snb.2018.12.099

Chen, Alice C. -H., Pena, Olga M., Nel, Hendrik J., Yerkovich, Stephanie T., Chang, Anne B., Baines, Katherine J., Gibson, Peter G., Petsky, Helen L., Pizzutto, Susan J., Hodge, Sandra, Masters, Ian B., Buntain, Helen L. and Upham, John W. (2018) Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles. Pediatric Pulmonology, 53 5: 575-582. doi:10.1002/ppul.23984

Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny (2018) Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development. Frontiers in Immunology, 9 JAN: 1-10. doi:10.3389/fimmu.2018.00008

Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Larrondo, Milton L., Aravena, Octavio, Molina, Mar-A C., Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2017) Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response. Frontiers in Immunology, 8 OCT: 1350. doi:10.3389/fimmu.2017.01350

Overgaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017) CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 3: 837-844. doi:10.1189/jlb.1AB0217-065R

Benham, Helen, Nel, Hendrik J., Law, Soi Cheng, Mehdi, Ahmed M., Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Lee, Bernett T., Ng, Jennifer, Brunck, Marion E. G., Hyde, Claire, Trouw, Leendert A., Dudek, Nadine L., Purcell, Anthony W., O'Sullivan, Brendan J., Connolly, John E., Paul, Sanjoy K., Le Cao, Kim-Anh and Thomas, Ranjeny (2015) Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients. Science Translational Medicine, 7 290: 290ra87.1-290ra87.11. doi:10.1126/scitranslmed.aaa9301

Nel, Hendrik J., du Plessis, Nelita, Kleynhans, Leanie, Loxton, Andre G., van Helden, Paul D. and Walzl, Gerhard (2014) Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogens. BMC Microbiology, 14 1: . doi:10.1186/1471-2180-14-9

Scalfone, Lisa K., Nel, Hendrik J., Gagliardo, Lucille F., Cameron, Jody L., Al-Shokri, Shaikha, Leifer, Cynthia A., Fallon, Padraic G. and Appleton, Judith A. (2013) Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis. Infection and Immunity, 81 4: 1354-1363. doi:10.1128/IAI.01307-12

Knosp, Camille A., Schiering, Chris, Spence, Shaun, Carroll, Helen P., Nel, Hendrick J., Osbourn, Megan, Jackson, Ruaidhri, Lyubomska, Oksana, Malissen, Bernard, Ingram, Rebecca, Fitzgerald, Denise C., Powrie, Fiona, Fallon, Padraic G., Johnston, James A. and Kissenpfennig, Adrien (2013) Regulation of Foxp3(+) Inducible Regulatory T Cell Stability by SOCS2. Journal of Immunology, 190 7: 3235-3245. doi:10.4049/jimmunol.1201396

Scally, Stephen W., Petersen, Jan, Law, Soi Cheng, Dudek, Nadine L., Nel, Hendrik J., Loh, Khai Lee, Wijeyewickrema, Lakshmi C., Eckle, Sidonia B.G., van Heemst, Jurgen, Pike, Robert N., McCluskey, James, Toes, Rene E., La Gruta, Nicole L., Purcell, Anthony W., Reid, Hugh H., Thomas, Ranjeny and Rossjohn, Jamie (2013) A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine, 210 12: 2569-2582. doi:10.1084/jem.20131241

Law, Soi Cheng, Street, Shayna, Yu, Chien-Hsiung Alan, Capini, Christelle, Ramnoruth, Sakoontalla, Nel, Hendrik J., van Gorp, Eline, Hyde, Claire, Lau, Kim, Pahau, Helen, Purcell, Anthony W. and Thomas, Ranjeny (2012) T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Research and Therapy, 14 3: R118.1-R118.12. doi:10.1186/ar3848

Viejo-Borbolla, Abel, Martinez-Martin, Nadia, Nel, Hendrik J., Rueda, Patricia, Martin, Rocio, Blanco, Soledad, Arenzana-Seisdedos, Fernando, Thelen, Marcus, Fallon, Padraic G. and Alcami, Antonio (2012) Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses. PloS Pathogens, 8 2: . doi:10.1371/journal.ppat.1002497

Knosp, Camille A., Carroll, Helen P., Elliott, Joanne, Saunders, Sean P., Nel, Hendrik J., Amu, Sylvie, Pratt, Joanne C., Spence, Shaun, Doran, Emma, Cooke, Nicola, Jackson, Ruaidhri, Swift, Jonathan, Fitzgerald, Denise C., Heaney, Liam G., Fallon, Padraic G., Kissenpfennig, Adrien and Johnston, James A. (2011) SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses. Journal of Experimental Medicine, 208 7: 1523-1531. doi:10.1084/jem.20101167

Ryan, Anthony, Lynch, Mark, Smith, Sinead M., Amu, Sylvie, Nel, Hendrik J., McCoy, Claire E., Dowling, Jennifer K., Draper, Eve, O'Reilly, Vincent, McCarthy, Ciara, O'Brien, Julie, Eidhin, Deirdre Ni, O'Connell, Mary J., Keogh, Brian, Morton, Charles O., Rogers, Thomas R., Fallon, Padraic G., O'Neill, Luke A., Kelleher, Dermot and Loscher, Christine E. (2011) A role for TLR4 in clostridium difficile infection and the recognition of surface layer proteins. PloS Pathogens, 7 6: . doi:10.1371/journal.ppat.1002076

Nel, Hendrik J., Hams, Emily, Saunders, Sean P., Mangan, Niamh E., Smith, Philip, Atzberger, Ann, Flavell, Richard A., Akira, Shizuo, McKenzie, Andrew N. and Fallon, Padraic G. (2011) Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice. Journal of Immunology, 186 8: 4631-4639. doi:10.4049/jimmunol.1002995

Downer, Eric J., Clifford, Eileen, Gran, Bruno, Nel, Hendrik J., Fallon, Padraic G. and Moynagh, Paul N. (2011) Identification of the Synthetic Cannabinoid R(+) WIN55,212-2 as a Novel Regulator of IFN Regulatory Factor 3 Activation and IFN-beta Expression RELEVANCE TO THERAPEUTIC EFFECTS IN MODELS OF MULTIPLE SCLEROSIS. Journal of Biological Chemistry, 286 12: 10316-10328. doi:10.1074/jbc.M110.188599

Adisakwattana, Poom, Saunders, Sean P., Nel, Hendrik J. and Fallon, Padraic G. (2009) Helminth-derived immunomodulatory molecules. Advances in Experimental Medicine and Biology, 666 95-107. doi:10.1007/978-1-4419-1601-3_8

Ni Ainle, Fionnuala, Preston, Roger J. S., Jenkins, P. Vincent, Nel, Hendrik J., Johnson, Jennifer A., Smith, Owen P., White, Barry, Fallon, Padraic G. and O'Donnell, James S. (2009) Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation. Blood, 114 8: 1658-1665. doi:10.1182/blood-2009-05-222109

Walzl, Gerhard , Hussell, Tracy and Nel, Hendrik J. (2004) Is the hygiene effect bad news for the control of infectious diseases?. Current Allergy and Clinical Immunology, 17 4: 180-186.

Rossouw, Manda, Nel, Hendrik J., Cooke, Graham S., van Helden, Paul D. and Hoal, Eileen G. (2003) Association between tuberculosis and a polymorphic NFκB binding site in the interferon γ gene. The Lancet, 361 9372: 1871-1872. doi:10.1016/s0140-6736(03)13491-5

Jansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Koppejan, Hester, Hameetman, Marjolijn, Liu, Ligong, Corbett, Alexandra, Eckle, Sidonia, Fairlie, David, Toes, Rene E. M., van Gaalen, Floris, Rossjohn, Jamie, McCluskey, James and Thomas, Ranjeny (2017). Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis. In: 2017 ACR/ARHP Annual Meeting, San Diego, California, (3918-2919). 3-8 November 2017.

Galea, Ryan, Nel, Hendrik, Talekar, Meghna, Cole, Suzanne, Cochlin, Karyn, Hitchcock, Shannon, Zeng, Bijun, Yekollu, Suman, Rossjohn, Jamie, Reid, Hugh, Malaviya, Ravi, Shealy, Dave, O'Sullivan, Brendan and Thomas, Ranjeny (2017). Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis. In: 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, California, (). 3-8 November 2017.

Bergot, Anne-Sophie, Talekar, Meghna, Nel, Hanno, Galea, Ryan, Harris, Mark, Hamilton-Williams, Emma and Thomas, Ranjeny (2017). Antigen specific immunotherapy for autoimmune disease targeting dendritic cells. In: 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS), Kanazawa Japan, (66-66). 29 October - 2 November 2017.

Law, Soi Cheng, Nel, Hendrik, Rossjohn, Jamie, Reid, Hugh H., La Gruta, Nicole L. and Thomas, Ranjeny (2015). Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients. In: Arthritis & Rheumatology. , , (). .

Law, S., Rossjohn, J., Nel, H., La Gruta, N., Reid, H. and Thomas, R. (2015). Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell Level. In: Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting, Adelaide, South Australia, (25-25). 23–26 May 2015. doi:10.1111/imj.12752

Law, Soi-Cheng, Nel, Hendrik, Mehdi, Ahmed, Le Cao, Kim-Anh and Thomas, Ranjeny (2014). Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.. In: Special Issue: 2014 ACR/ARHP Annual Meeting Abstract Supplemen. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, (S422-S422). 14-19 November 2014. doi:10.1002/art.38914

Klinken, Elizabeth, Nel, Hanno and Thomas, Ranjeny (2013). Mucosal Associated Invariant T (Mait) Cell Numbers Are Reduced in the Peripheral Blood of Rheumatoid Arthritis Patients. In: Special Issue: Australasian Society of Clinical Immunology and Allergy (ASCIA) 24th Annual Scientific Meeting. Australasian Society of Clinical Immunology and Allergy (ASCIA) 24th Annual Scientific Meeting, Perth, Western Australia, (10-10). 11-13 September 1013. doi:10.1111/imj.12252

Nel, H., Law, S., Street, S., Ramnoruth, N., Shams, R., Pahau, H., Brunck, M., Hyde, C., O'Sullivan, B., Capini, C., Tran, A., Ng, J., Godfrey, D. and Thomas, R. (2012). Outcome of a phase I trial of rheumavax in patients with rheumatoid arthritis. In: Special Issue: Australian Rheumatology Association in conjunction with Rheumatology Health Professionals 53rd Annual Scientific Meeting. 53rd Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals, Canberra ACT, Australia, (10-10). 12-15 May 2012. doi:10.1111/j.1445-5994.2012.02761.x

Dr Hanno Nel

Publications

Book Chapter

Journal Articles

Conference Papers