Dr Xiaowen Liang
UQ Development Fellow
The University of Queensland Diamantina Institute
+61 7 344 37487
Book Chapters
Holmes, Amy, Thorling, Camilla, Liu, Xin, Liang, Xiaowen, Wang, Haolu, Breunig, Hans G., König, Karsten, Studier, Hauke and Roberts, Michael S. (2018). Revealing interaction of dyes and nanomaterials with organs by imaging. In Karsten König (Ed.), Multiphoton microscopy and fluorescence lifetime imaging (pp. 345-368) Berlin, Germany: DeGruyter. doi:10.1515/9783110429985-020
Liang, Xiaowen, Wang, Haolu, Liu, Xin, Grice, Jeffrey, Xu, Zhi Ping and Roberts, Michael S. (2017). Related topic: Safety evaluation of nanomaterials. In Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds (pp. 313-322) Tokyo, Japan: Springer . doi:10.1007/978-4-431-56526-0_28
Liu, X., Wang, H., Liang, X. and Roberts, M. S. (2017). Hepatic metabolism in liver health and disease. In Pablo Muriel (Ed.), Liver Pathophysiology: Therapies and Antioxidants (pp. 391-400) Cambridge, United Kingdom: Academic Press. doi:10.1016/B978-0-12-804274-8.00030-8
Thorling, Camilla A., Holmes, Amy, Studier, Hauke, Liu, David, Liang, Xiaowen and Roberts, Michael S. (2016). Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. In Stefan G. Stanciu (Ed.), Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver (pp. 107-123) Rijeka, Croatia: InTech. doi:10.5772/63452
Journal Articles
Chen, Tao, Tu, Shaoxiong, Wang, Haolu, Liu, Xuesong, Li, Fenghua, Jin, Wang, Liang, Xiaowen, Zhang, Xiaoqun and Wang, Jian (2020) Computer-aided diagnosis of gallbladder polyps based on high resolution ultrasonography. Computer Methods and Programs in Biomedicine, 185 105118. doi:10.1016/j.cmpb.2019.105118
Ruan, Qi, Haolu Wang, Burke, Leslie J., Bridle, Kim R., Li, Xinxing, Chunxia Zhao, Crawford, Darrell Henry G., Roberts, Michael S. and Xiaowen Liang (2020) Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma. International Journal of Cancer, .doi:10.1002/ijc.32899
Li, Xinxing, Teng, Shifeng, Zhang, Yanyan, Zhang, Weigang, Zhang, Xianwen, Xu, Kai, Yao, Houshan, Yao, Jun, Wang, Haolu, Liang, Xiaowen and Hu, Zhiqian (2019) Erratum: TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT (Oncotarget (2017) 8 (47052–47063) DOI: 10.18632/oncotarget.16789). OncoTarget, 10 60: 6540-6540. doi:10.18632/oncotarget.27299
Wei, Shuxun, Chen, Jinshui, Huang, Yu, Sun, Qiang, Wang, Haolu, Liang, Xiaowen, Hu, Zhiqian and Li, Xinxing (2019) Identification of hub genes and construction of transcriptional regulatory network for the progression of colon adenocarcinoma hub genes and TF regulatory network of colon adenocarcinoma. Journal of Cellular Physiology, . doi:10.1002/jcp.29067
Nastiti, Christofori M.R.R., Mohammed, Yousuf, Telaprolu, Krishna C., Liang, Xiaowen, Grice, Jeffrey E., Roberts, Michael S. and Benson, Heather A.E. (2019) Evaluation of quantum dot skin penetration in porcine skin: effect of age and anatomical site of topical application. Skin Pharmacology and Physiology, 1-10. doi:10.1159/000499435
Yang, Chengcheng, Mi, Xuan, Su, Huilan, Yang, Jingxing, Gu, Yiyun, Zhang, Lu, Sun, Wenshe, Liang, Xiaowen and Zhang, Chunfu (2019) GE11-PDA-Pt@USPIOs nano-formulation for relief of tumor hypoxia and MRI/PAI-guided tumor radio-chemotherapy. Biomaterials Science, 7 5: 2076-2090. doi:10.1039/c8bm01492b
Zhang, Lu, Su, Huilan, Wang, Haolu, Li, Qian, Li, Xiao, Zhou, Chuanqing, Xu, Jia, Chai, Yimin, Liang, Xiaowen, Xiong, Liqin and Zhang, Chunfu (2019) Tumor chemo-radiotherapy with rod-shaped and spherical gold nano probes: shape and active targeting both matter. Theranostics, 9 7: 1893-1908. doi:10.7150/thno.30523
Xiao, Wenjin, Green, Thomas I. P., Liang, Xiaowen, Delint, Rosalia Cuahtecontzi, Perry, Guillaume, Roberts, Michael S., Le Vay, Kristian, Back, Catherine R., Ascione, Raimomdo, Wang, Haolu, Race, Paul R. and Perriman, Adam W. (2019) Designer artificial membrane binding proteins to direct stem cells to the myocardium. Chemical Science, 10 32: 7610-7618. doi:10.1039/c9sc02650a
Wang, Haolu, Lu, Hao, Yang, Haotian, Zhang, Xianwen, Thompson, Erik W., Roberts, Michael S., Hu, Zhigian, Liang, Xiaowen and Li, Xinxing (2019) Impact of age on risk of lymph node positivity in patients with colon cancer. Journal of Cancer, 10 9: 2102-2108. doi:10.7150/jca.28377
Xie, Yayun, Huang, Yu, Ruan, Qi, Wang, Haolu, Liang, Xiaowen, Hu, Zhiqian and Li, Xinxing (2019) Impact of Tumor Site on Lymph Node Status and Survival in Colon Cancer. Journal of Cancer, 10 11: 2376-2383. doi:10.7150/jca.32038
Wang, Haolu, Yang, Haotian, Xu, Zhi Ping, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018) Anionic long-circulating quantum dots for long-term intravital vascular imaging. Pharmaceutics, 10 4: 244. doi:10.3390/pharmaceutics10040244
Yang, Haotian, Villani, Rehan M., Wang, Haolu, Simpson, Matthew J., Roberts, Michael S., Tang, Min and Liang, Xiaowen (2018) The role of cellular reactive oxygen species in cancer chemotherapy. Journal of Experimental and Clinical Cancer Research, 37 1: 266. doi:10.1186/s13046-018-0909-x
He, Haihong, Liu, Yuxin, Zhou, Zhongneng, Guo, Chunlei, Wang, Hong-Yin, Wang, Zhuang, Wang, Xueli, Zhang, Ziqian, Wu, Fu-Gen, Wang, Haolu, Chen, Daijie, Yang, Dahai, Liang, Xiaowen, Chen, Jinquan, Zhou, Shengmin, Liang, Xin, Qian, Xuhong and Yang, Youjun (2018) A photo-triggered and photo-calibrated nitric oxide donor: rational design, spectral characterizations, and biological applications. Free Radical Biology and Medicine, 123 1-7. doi:10.1016/j.freeradbiomed.2018.04.563
Luo, Xiao, Yang, Haotian, Wang, Haolu, Ye, Zhiwei, Zhou, Zhongneng, Gu, Luyan, Chen, Jinquan, Xiao, Yi, Liang, Xiaowen, Qian, Xuhong and Yang, Youjun (2018) Highly sensitive hill-type small-molecule pH probe that recognizes the reversed pH gradient of cancer cells. Analytical Chemistry, 90 9: 5803-5809. doi:10.1021/acs.analchem.8b00218
He, Haihong, Xia, Yang, Qi, Yingxue, Wang, Hong-Yin, Wang, Zhuang, Bao, Jianming, Zhang, Ziqian, Wu, Fu-Gen, Wang, Haolu, Chen, Daijie, Yang, Dahai, Liang, Xiaowen, Chen, Jinquan, Zhou, Shengmin, Liang, Xin, Qian, Xuhong and Yang, Youjun (2018) A Water-Soluble, Green-Light Triggered, and Photo-Calibrated Nitric Oxide Donor for Biological Applications. Bioconjugate Chemistry, 29 4: 1194-1198. doi:10.1021/acs.bioconjchem.7b00821
Jin, Wang, Liang, Xiaowen, Brooks, Anastasia, Futrega, Kathryn, Liu, Xin, Doran, Michael R., Simpson, Matthew J., Roberts, Michael S. and Wang, Haolu (2018) Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice. PeerJ, 2018 12: e6072. doi:10.7717/peerj.6072
Wang, Haolu, Li, Xinxing, Tse, Brian Wan-Chi, Yang, Haotian, Thorling, Camilla A., Liu, Yuxin, Touraud, Margaux, Chouane, Jean Batiste, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018) Indocyanine green-incorporating nanoparticles for cancer theranostics. Theranostics, 8 5: 1227-1242. doi:10.7150/thno.22872
Lu, Hao, Guo, Rong, Yang, Haotian, Wang, Haolu, Liang, Xiaowen, Hu, Zhiqian and Li, Xinxing (2017) The prognostic value of negative lymph node count for patients with cervical cancer after radical surgery. Oncotarget, 9 2: 2810-2818. doi:10.18632/oncotarget.23596
Brooks, Anastasia, Futrega, Kathryn, Liang, Xiaowen, Hu, Xiaoling, Liu, Xin, Crawford, Darrell H. G., Doran, Michael R., Roberts, Michael S. and Wang, Haolu (2017) Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells. Stem Cells Translational Medicine, 7 1: 78-86. doi:10.1002/sctm.17-0209
Wang, Haolu, Thorling, Camilla A., Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017) Visualization and Modeling of the In Vivo Distribution of Mesenchymal Stem Cells. Current Protocols in Stem Cell Biology, 43 1-17. doi:10.1002/cpsc.39
Li, Xinxing, Wang, Weijun, Ruan, Canping, Wang, Yi, Wang, Haolu, Liang, Xiaowen, Sun, Yanping and Hu, Zhiqian (2017) Age-specific impact on the survival of gastric cancer patients with distant metastasis: an analysis of SEER database. Oncotarget, 8 57: 97090-97100. doi:10.18632/oncotarget.21350
Li, Xinxing, Liu, Ye, Wang, Yi, Ruan, Canping, Wang, Haolu, Liang, Xiaowen, Sun, Yanping and Hu, Zhiqian (2017) The influence of marital status on survival of gallbladder cancer patients: a population-based study. Scientific Reports, 7 1: 5322. doi:10.1038/s41598-017-05545-0
Zhou, Ling-ling, Zhou, Cong, Liang, Xiao-wen, Feng, Zhe, Liu, Zhang-pu, Wang, Hao-lu and Zhou, Xue-ping (2017) Self-protection against triptolide-induced toxicity in human hepatic cells via Nrf2-ARE-NQO1 pathway. Chinese Journal of Integrative Medicine, 23 12: 929-936. doi:10.1007/s11655-017-2546-6
Li, Xinxing, Teng, Shifeng, Zhang, Yanyan, Zhang, Weigang, Zhang, Xianwen, Xu, Kai, Yao, Houshan, Yao, Jun, Wang, Haolu, Liang, Xiaowen and Hu, Zhiqian (2017) TROP2 promotes proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K/AKT pathway and inducing EMT. OncoTarget, 8 29: 47052-47063. doi:10.18632/oncotarget.16789
Liu, Xin, Liang, Xiaowen, Wang, Haolu, Roberts, Darren M. and Roberts, Michael S. (2017) Multiphoton imaging for assessing renal disposition in acute kidney injury. SPIE Biophotonics Australasia, 10013 . doi:10.1117/12.2242964
Wang, Haolu, Zhang, Run, Bridle, Kim R., Jayachandran, Aparna, Thomas, James A., Zhang, Wenzhu, Yuan, Jingli, Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017) Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific Reports, 7 1: 45374. doi:10.1038/srep45374
Li, Xinxing, Lu, Hao, Xu, Kai, Wang, Haolu, Liang, Xiaowen and Hu, Zhiqian (2017) Negative lymph node count is an independent prognostic factor for patients with rectal cancer who received preoperative radiotherapy. BMC Cancer, 17 1: . doi:10.1186/s12885-017-3222-8
Li, Xinxing, Zhang, Weigang, Zhang, Xianwen, Wang, Haolu, Xu, Kai, Yao, Houshan, Yao, Jun, Liang, Xiaowen and Hu, Zhiqian (2017) The prognostic value of negative lymph node count for patients with gastric cancer who received preoperative radiotherapy. Oncotarget, 8 29: 46946-46954. doi:10.18632/oncotarget.14943
Zhang, Feiyue, Liang, Xiaowen, Zhang, Wenzhu, Wang, Yong-Lei, Wang, Haolu, Mohammed, Yousuf H., Song, Bo, Zhang, Run and Yuan, Jingli (2017) A unique iridium(III) complex-based chemosensor for multi-signal detection and multi-channel imaging of hypochlorous acid in liver injury. Biosensors and Bioelectronics, 87 1005-1011. doi:10.1016/j.bios.2016.09.067
Teng, Shifeng, Xu, Kai, Yao, Jun, Zhang, Xianwen, Li, Mingming, Zhang, Yanyan, Zhang, Weigang, Wang, Haolu, Liang, Xiaowen, Li, Xinxing and Hu, Zhiqian (2017) Exploration of the optimal lymph node count retrieved for patients with node-negative colonic mucinous cancer. International Journal of Clinical and Experimental Medicine, 10 12: 16625-16631.
Ni, Qihong, Wang, Haolu, Zhang, Yunhe, Qian, Lijun, Chi, Jiachang, Liang, Xiaowen, Chen, Tao and Wang, Jian (2016) MDCT assessment of resectability in hilar cholangiocarcinoma. Abdominal Radiology, 42 3: 1-10. doi:10.1007/s00261-016-0943-0
Li, Xinxing, Wang, Haolu, Wang, Juan, Chen, Yuying, Yin, Xiaobin, Shi, Guiying, Li, Hui, Hu, Zhiqian and Liang, Xiaowen (2016) Emodin enhances cisplatin-induced cytotoxicity in human bladder cancer cells through ROS elevation and MRP1 downregulation. Bmc Cancer, 16 1: . doi:10.1186/s12885-016-2640-3
Liang, Xiaowen, Garcia, Brandon L., Visai, Livia, Prabhakaran, Sabitha, Meenan, Nicola A. G., Potts, Jennifer R., Humphries, Martin J. and Höök, Magnus (2016) Allosteric regulation of fibronectin/α5 β1 interaction by fibronectin-binding MSCRAMMs. PLoS ONE, 11 7: . doi:10.1371/journal.pone.0159118
Wang, Haolu, Liang, Xiaowen, Gravot, Germain, Thorling, Camilla A., Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2016) Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy. Journal of Biophotonics, 10 1: 46-60. doi:10.1002/jbio.201600083
Ni, Qihong, Wang, Haolu, Liang, Xiaowen, Zhang, Yunhe, Chen, Wei and Wang, Jian (2016) Successful parenchyma-sparing anatomical surgery by 3-dimensional reconstruction of hilar cholangiocarcinoma combined with anatomic variation. Journal of the College of Physicians and Surgeons Pakistan, 26 S1: S13-S15.
Wang, Haolu, Liang, Xiaowen, Xu, Zhi Ping, Crawford, Darrell H. G, Liu, Xin and Roberts, Michael S. (2016) A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells. Scientific Reports, 6 e22293.1-e22293.12. doi:10.1038/srep22293
Liang, Xiaowen, Wang, Haolu, Grice, Jeffrey E., Li, Li, Liu, Xin, Xu, Zhi Ping and Roberts, Michael S. (2016) Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles. Nano Letters, 16 2: 939-945. doi:10.1021/acs.nanolett.5b03854
Liang, Xiaowen, Wang, Haolu, Zhu, Yian, Zhang, Run, Cogger, Victoria C., Liu, Xin, Xu, Zhi Ping, Grice, Jeffrey E. and Roberts, Michael S. (2016) Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney. Acs Nano, 10 1: 387-395. doi:10.1021/acsnano.5b05066
Jin, Yue, Wang, Haolu, Ma, Xiaowei, Liang, Xiaowen, Liu, Xin and Wang, Yu (2015) Clinicopathological characteristics of gynecological cancer associated with hypoxia-inducible factor 1α expression: a meta-analysis including 6,612 subjects. PLoS ONE, 10 5: e0127229. doi:10.1371/journal.pone.0127229
Wang, Haolu, Liang, Xiaowen, Mohammed, Yousuf H., Thomas, James A., Bridle, Kim R., Thorling, Camilla A., Grice, Jeffrey E., Xu, Zhi Ping, Liu, Xin, Crawford, Darrell H. G. and Roberts, Michael S. (2015) Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging. Biomedical Optics Express, 6 3: 780-792. doi:10.1364/BOE.6.000780
Wang, Haolu, Thorling, Camilla A., Liang, Xiaowen, Bridle, Kim R., Grice, Jeffrey E., Zhu, Yian, Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts MS (2015) Diagnostic imaging and therapeutic application of nanoparticles targeting the liver. Journal of Materials Chemistry B, 3 6: 939-958. doi:10.1039/C4TB01611D
Jin, Yue, Wang, Haolu, Liang, Xiaowen, Ma, Jun and Wang, Yu (2014) Pathological and prognostic significance of hypoxia-inducible factor 1α expression in epithelial ovarian cancer: a meta-analysis. Tumor Biology, 35 8: 8149-8159. doi:10.1007/s13277-014-2059-x
Wang, Hui, Wang, Haolu, Chen, Tao, Liang, Xiaowen, Song, Yanyan and Wang, Jian (2014) Evaluation of the POSSUM, P-POSSUM and E-PASS scores in the surgical treatment of hilar cholangiocarcinoma. World Journal of Surgical Oncology, 12 1: . doi:10.1186/1477-7819-12-191
Liang X., Grice J.E., Zhu Y., Liu D., Sanchez W.Y., Li Z., Crawford D.H.G., Le Couteur D.G., Cogger V.C., Liu X., Xu Z.P. and Roberts M.S. (2014) Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sinusoidal liver cells. Small, 11 14: 1711-1720. doi:10.1002/smll.201402698
Liang, Xiao Wen, Xu, Zhi Ping, Grice, Jeffrey, Zvyagin, Andrei V., Roberts, Michael S. and Liu, Xin (2013) Penetration of Nanoparticles into Human Skin. Current Pharmaceutical Design, 19 35: 6353-6366. doi:10.2174/1381612811319350011
Conference Papers
Roberts, Michael S., Barkauskas, Deborah, Wang, Haolu, Liu, Xin, Studier, Hauke, Pastore, Michael, Zhang, Run, Holmes, Amy, Grice, Jeffrey E., Xu, Zhiping, Mohammed, Yousuf S. and Liang, Xiaowen (2020). Multiphoton and FLIM imaging in quantifying ex vivo and in vivo body organ kinetics of solutes. In: Ammasi Periasamy, Peter T. So and Karsten König, Multiphoton Microscopy in the Biomedical Sciences XX. Multiphoton Microscopy in the Biomedical Sciences, San Francisco, California, (). 2-4 February 2020. doi:10.1117/12.2546058
Liang, X., Wang, H., Liu, X., Touraud, M., Chouane, J. B., Tse, B. and Roberts, M. S. (2017). Novel mechanistic imaging biomarkers for early prediction of acetaminophen-induced hepatotoxicity. In: Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, , Gold Coast, Queensland, Australia, (8-8). 20–22 Aug 2017.
Wang, H., Liang, X., Weijs, L., Brooks, A., Liu, X., Roberts, M. S. and Crawford, D. H. G. (2017). Characterizing and predicting the in vivo kinetics of mesenchymal stem cells and their secretome for the treatment of liver cirrhosis. In: Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, Queensland, (12-12). 20–22 Aug 2017.
Thorling (Thompson), Camilla, Wang, Haolu, Liu, Xin, Liang, Xiaowen, Crawford, Darrell H. G. and Roberts, Michael S. (2017). Non-invasive assessment of the liver using imaging. In: Hutchinson, MR and Goldys, EM, Spie Biophotonics Australasia. SPIE BioPhotonics Australasia Conference, Adelaide, SA, Australia, (). 17 - 19 October 2016. doi:10.1117/12.2242883
Liang, Xiaowen, Wang, Haolu, Liu, Xin and Roberts, Michael (2017). Quantitative optical imaging of paracetamol-induced metabolism changes in the liver. In: Hutchinson, MR and Goldys, EM, SPIE BioPhotonics Australasia. SPIE BioPhotonics Australasia, Adelaide, SA, Australia, (). 17 - 19 October 2016. doi:10.1117/12.2242962
Wang, Haolu, Jayachandran, Aparna, Gravot, Germain, Liang, Xiaowen, Thorling, Camilla A., Zhang, Run, Liu, Xin and Roberts, Michael S. (2017). In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe. In: Hutchinson, MR and Goldys, EM, Spie Biophotonics Australasia. SPIE BioPhotonics Australasia Conference, Adelaide,SA, Australia, (). 17 - 19 October 2016. doi:10.1117/12.2242978
Wang, H., Liang, X., Endo-Munoz, L., Weijs, L., Liu, X., Crawford, D. and Roberts, M. (2015). A blood-flow limited physiologically based kinetic model to characterize and predict the biological fate of mesenchymal stem cells in vivo. In: Journal of Gastroenterology and Hepatology. Gastro 2015 GESA‐AGW And WGO International Congress, Gastroenterological Society Of Australia Australian Gastroenterology Week 2015 - World Congress Of Gastroenterology, , Brisbane, Queensland, Australia, (11-11). 28 September‐2 October 2015.
Liang, X., Wang, H., Zhu, Y., Grice, J., Liu, X., Xu, Z. and Roberts, M. (2015). Early diagnosis of hepatocellular carcinoma by in vivo imaging. In: European Cancer Congress, Vienna, Austria, (S129-S130). 2015. doi:10.1016/S0959-8049(16)30378-1
Wang, H., Liang, X., Thorling, C., Xu, Z. P., Crawford, D., Liu, X. and Roberts, M. (2015). A physiologically based kinetic model to characterize and predict the biological fate of circulating tumor cells in vivo. In: European Cancer Congress, Vienna, Austria, (S133-S133). 2015.
Thesis
Liang, Xiaowen (2015). Biodistribution of newly developed water-dispersible CdTe/CdS quantum dots for in vivo imaging PhD Thesis, School of Medicine, The University of Queensland. doi:10.14264/uql.2015.503