Publications
Journal Articles
Banushi, Blerida and Simpson, Fiona (2022). Overlapping machinery in lysosome-related organelle trafficking: a lesson from rare multisystem disorders. Cells, 11 (22) 3702, 1-26. doi: 10.3390/cells11223702
Joseph, Shannon R., Lum, Benedict, Banushi, Blerida, Barry, Rachael, Panizza, Benedict, Walpole, Euan and Simpson, Fiona (2020). Antibody/ligand-target receptor internalization assay protocol using fresh human or murine tumor ex vivo samples. STAR Protocols, 1 (2) 100087, 100087. doi: 10.1016/j.xpro.2020.100087
Chew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019
Patel, Nina, Mills, Philippa, Davison, James, Cleary, Maureen, Gissen, Paul, Banushi, Blerida, Doykov, Ivan, Dorman, Megan, Mills, Kevin and Heywood, Wendy E. (2020). Free urinary glycosylated hydroxylysine as an indicator of altered collagen degradation in the mucopolysaccharidoses. Journal of Inherited Metabolic Disease, 43 (2), 309-317. doi: 10.1002/jimd.12166
Scietti, Luigi, Chiapparino, Antonella, De Giorgi, Francesca, Fumagalli, Marco, Khoriauli, Lela, Nergadze, Solomon, Basu, Shibom, Olieric, Vincent, Cucca, Lucia, Banushi, Blerida, Profumo, Antonella, Giulotto, Elena, Gissen, Paul and Forneris, Federico (2018). Author Correction: Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3. Nature communications, 9 (1) 3912, 3912. doi: 10.1038/s41467-018-06481-x
Baruteau, Julien, Perocheau, Dany P., Hanley, Joanna, Lorvellec, Maelle, Rocha-Ferreira, Eridan, Karda, Rajvinder, Ng, Joanne, Suff, Natalie, Diaz, Juan Antinao, Rahim, Ahad A., Hughes, Michael P., Banushi, Blerida, Prunty, Helen, Hristova, Mariya, Ridout, Deborah A., Virasami, Alex, Heales, Simon, Howe, Stewen J., Buckley, Suzanne M. K., Mills, Philippa B., Gissen, Paul and Waddington, Simon N. (2018). Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer. Nature Communications, 9 (1) 3505. doi: 10.1038/s41467-018-05972-1
Scietti, Luigi, Chiapparino, Antonella, De Giorgi, Francesca, Fumagalli, Marco, Khoriauli, Lela, Nergadze, Solomon, Basu, Shibom, Olieric, Vincent, Cucca, Lucia, Banushi, Blerida, Profumo, Antonella, Giulotto, Elena, Gissen, Paul and Forneris, Federico (2018). Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3. Nature Communications, 9 (1) 3163, 3912. doi: 10.1038/s41467-018-05631-5
Joseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018). An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, 139 (1), 213-223. doi: 10.1016/j.jid.2018.06.190
Ludtmann, Marthe H. R., Angelova, Plamena R., Horrocks, Mathew H., Choi, Minee L., Rodrigues, Margarida, Baev, Artyom Y., Berezhnov, Alexey V., Yao, Zhi, Little, Daniel, Banushi, Blerida, Al-Menhali, Afnan Saleh, Ranasinghe, Rohan T., Whiten, Daniel R., Yapom, Ratsuda, Dolt, Karamjit Singh, Devine, Michael J., Gissen, Paul, Kunath, Tilo, Jaganjac, Morana, Pavlov, Evgeny V., Klenerman, David, Abramov, Andrey Y. and Gandhi, Sonia (2018). α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease. Nature Communications, 9 (1) 2293. doi: 10.1038/s41467-018-04422-2
Hanley, Joanna, Dhar, Dipok Kumar, Mazzacuva, Francesca, Fiadeiro, Rebeca, Burden, Jemima J., Lyne, Anne-Marie, Smith, Holly, Straatman-Iwanowska, Anna, Banushi, Blerida, Virasami, Alex, Mills, Kevin, Lemaigre, Frederic P., Knisely, A. S., Howe, Steven, Sebire, Neil, Waddington, Simon N., Paulusma, Coen C., Clayton, Peter and Gissen, Paul (2017). Vps33b is crucial for structural and functional hepatocyte polarity. Journal of Hepatology, 66 (5), 1001-1011. doi: 10.1016/j.jhep.2017.01.001
Gruber, Robert, Rogerson, Clare, Windpassinger, Christian, Banushi, Blerida, Straatman-Iwanowska, Anna, Hanley, Joanna, Forneris, Federico, Strohal, Robert, Ulz, Peter, Crumrine, Debra, Menon, Gopinathan K., Blunder, Stefan, Schmuth, Matthias, Mueller, Thomas, Smith, Holly, Mills, Kevin, Kroisel, Peter, Janecke, Andreas R. and Gissen, Paul (2017). Autosomal Recessive Keratoderma-Ichthyosis- Deafness (ARKID) Syndrome Is Caused by VPS33B Mutations Affecting Rab Protein Interaction and Collagen Modification. Journal of Investigative Dermatology, 137 (4), 845-854. doi: 10.1016/j.jid.2016.12.010
Banushi, Blerida, Forneris, Federico, Straatman-Iwanowska, Anna, Strange, Adam, Lyne, Anne-Marie, Rogerson, Clare, Burden, Jemima J., Heywood, Wendy E., Hanley, Joanna, Doykov, Ivan, Straatman, Kornelis R., Smith, Holly, Bem, Danai, Kriston-Vizi, Janos, Ariceta, Gema, Risteli, Maija, Wang, Chunguang, Ardill, Rosalyn E., Zaniew, Marcin, Latka-Grot, Julita, Waddington, Simon N., Howe, S. J., Ferraro, Francesco, Gjinovci, Asllan, Lawrence, Scott, Marsh, Mark, Girolami, Mark, Bozec, Laurent, Mills, Kevin and Gissen, Paul (2016). Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis. Nature Communications, 7 (1) 12111. doi: 10.1038/ncomms12111
Deas, Emma, Cremades, Nunilo, Angelova, Plamena R., Ludtmann, Marthe H. R., Yao, Zhi, Chen, Serene, Horrocks, Mathew H., Banushi, Blerida, Little, Daniel, Devine, Michael J., Gissen, Paul, Klenerman, David, Dobson, Christopher M., Wood, Nicholas W., Gandhi, Sonia and Abramov, Andrey Y. (2016). Alpha-synuclein oligomers interact with metal ions to induce oxidative stress and neuronal death in Parkinson's disease. Antioxidants & Redox Signaling, 24 (7), 376-391. doi: 10.1089/ars.2015.6343
Bem, Danai, Smith, Holly, Banushi, Blerida, Burden, Jemima J., White, Ian J., Hanley, Joanna, Jeremiah, Nadia, Rieux-Laucat, Frederic, Bettels, Ruth, Ariceta, Gema, Mumford, Andrew D., Thomas, Steven G., Watson, Steve P. and Gissen, Paul (2015). VPS33B regulates protein sorting into and maturation of alpha-granule progenitor organelles in mouse megakaryocytes. Blood, 126 (2), 133-143. doi: 10.1182/blood-2014-12-614677
Smith, Holly, Galmes, Romain, Gogolina, Ekaterina, Straatman-Iwanowska, Anna, Reay, Kim, Banushi, Blerida, Bruce, Christopher K., Cullinane, Andrew R., Romero, Rene, Chang, Richard, Ackermann, Oanez, Baumann, Clarisse, Cangul, Hakan, Celik, Fatma Cakmak, Aygun, Canan, Coward, Richard, Dionisi-Vici, Carlo, Sibbles, Barbara, Inward, Carol, Kim, Chong Ae, Klumperman, Judith, Knisely, A. S., Watson, Steven P. and Gissen, Paul (2012). Associations among genotype, clinical phenotype, and intracellular localization of trafficking proteins in ARC syndrome. Human Mutation, 33 (12), 1656-1664. doi: 10.1002/humu.22155