Researcher biography

Paul Clarke is Director of The University of Queensland Diamantina Institute (UQDI), a leading translational medical research centre studying cancer, autoimmune diseases, infection and immunity, and the genetic basis of disease. Based at the $350 million Translational Research Instutute facility at the Princess Alexandra Hospital site in Woolloongabba, scientists and clinical researchers at UQDI develop new methods for the prevention, detection and treatment of human diseases. Paul Clarke joined UQ in 2017 from the University of Dundee in Scotland where he was Professor of Cancer Cell Biology and Associate Dean (Research) in the School of Medicine. As an undergraduate, he read Biochemistry at the University of Bristol and, for his PhD, carried out research on the control of metabolism by the AMP-activated protein kinase with D. Grahame Hardie FRS at Dundee. Subsequently he was a Wellcome Trust Research Fellow working on control of the cell cycle in the group of Eric Karsenti at the European Molecular Biology Laboratory, Heidelberg (1991-1994) and a Senior Research Fellow at the University of Manchester (1994-1998). He joined the University of Dundee as a Senior Lecturer in 1998 and was awarded a personal chair in 2005. Professor Clarke has received a UK Medical Research Council Career Development Award (2001), Royal Society-Wolfson Research Merit Award (2003) and research fellowships from The Wellcome Trust and Cancer Research UK. He is a Fellow of the Royal Society of Biology. He has served on grant review panels for MRC, BBSRC and Cancer Research UK and several other panels across Europe. Professor Clarke's current research interests are the molecular mechanisms of cell division, chromosome instability and mitotic cell death. He also carries out research into the cellular responses to anti-cancer drugs.

Areas of research