Dr Alexis de Sa Ribeiro Do Bonfim Melo
Postdoctoral Research Fellow/Resear
The University of Queensland Diamantina Institute
Publications
Journal Articles
Bonifácio, Bruno Souza, Bonfim‐Melo, Alexis, Mortara, Renato Arruda and Ferreira, Éden Ramalho (2022). Successful invasion of Trypanosoma cruzi trypomastigotes is dependent on host cell actin cytoskeleton. Journal of Eukaryotic Microbiology, 69 (3) e12903, e12903. doi: 10.1111/jeu.12903
Bonfim-Melo, Alexis, Noordstra, Ivar, Gupta, Shafali, Chan, Amy H., Jones, Mathew J.K., Schroder, Kate and Yap, Alpha S. (2022). Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death. Cell Reports, 38 (5) 110316, 110316. doi: 10.1016/j.celrep.2022.110316
Bonfim-Melo, Alexis, Duszyc, Kinga, Gomez, Guillermo A. and Yap, Alpha S. (2022). Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis. The European Physical Journal E, 45 (1) 9, 9. doi: 10.1140/epje/s10189-022-00163-9
Nguyen, Thanh Binh, Myung, Yoochan, de Sá, Alex G. C., Pires, Douglas E. V. and Ascher, David B. (2021). mmCSM-NA: accurately predicting effects of single and multiple mutations on protein–nucleic acid binding affinity. NAR Genomics and Bioinformatics, 3 (4) lqab109, lqab109. doi: 10.1093/nargab/lqab109
Medina, Camila Macedo, Ferreira, Éden Ramalho, Bonifácio, Bruno Souza, Mortara, Renato Arruda and Bonfim-Melo, Alexis (2021). Trypanosoma cruzi extracellular amastigotes engage Rac1 and Cdc42 to invade RAW macrophages. Microbes and Infection, 23 (8) 104837, 104837. doi: 10.1016/j.micinf.2021.104837
Ferreira, Eden R., Bonfim-Melo, Alexis, Burleigh, Barbara A., Costales, Jaime A., Tyler, Kevin M. and Mortara, Renato A. (2021). Parasite-mediated remodeling of the host microfilament cytoskeleton enables rapid egress of Trypanosoma cruzi following membrane rupture. mBio, 12 (3) e00988-21. doi: 10.1128/mbio.00988-21
Romão, Fabiano T., Martins, Fernando H., Hernandes, Rodrigo T., Ooka, Tadasuke, Santos, Fernanda F., Yamamoto, Denise, Bonfim-Melo, Alexis, Jones, Nina, Hayashi, Tetsuya, Elias, Waldir P., Sperandio, Vanessa and Gomes, Tânia A. T. (2020). Genomic properties and temporal analysis of the interaction of an invasive Escherichia albertii with epithelial cells. Frontiers in Cellular and Infection Microbiology, 10 571088, 1-14. doi: 10.3389/fcimb.2020.571088
Ferreira, Bianca Lima, Ferreira, Éden Ramalho, Bonfim-Melo, Alexis, Mortara, Renato Arruda and Bahia, Diana (2019). Trypanosoma cruzi extracellular amastigotes selectively trigger the PI3K/Akt and Erk pathways during HeLa cell invasion. Microbes and Infection, 21 (10), 485-489. doi: 10.1016/j.micinf.2019.06.003
Rodrigues, João Paulo Ferreira, Souza Onofre, Thiago, Barbosa, Bruno Couto, Ferreira, Éden Ramalho, Bonfim‐Melo, Alexis and Yoshida, Nobuko (2019). Host cell protein LAMP‐2 is the receptor for Trypanosoma cruzi surface molecule gp82 that mediates invasion. Cellular Microbiology, 21 (5) e13003, e13003. doi: 10.1111/cmi.13003
Bonfim-Melo, Alexis, Ferreira, Eden R., Florentino, Pilar T.V. and Mortara, Renato A. (2018). Amastigote synapse: the tricks of Trypanosoma cruzi extracellular amastigotes. Frontiers in Microbiology, 9 (JUN) 1341. doi: 10.3389/fmicb.2018.01341
Bonfim-Melo, Alexis, Ferreira, Éden R. and Mortara, Renato A. (2018). Rac1/WAVE2 and Cdc42/N-WASP participation in actin-dependent host cell invasion by extracellular amastigotes of Trypanosoma cruzi. Frontiers in Microbiology, 9 (FEB) 360, 360. doi: 10.3389/fmicb.2018.00360
Ferreira, Éden R., Bonfim-Melo, Alexis, Cordero, Esteban M. and Mortara, Renato A. (2017). ERM proteins play distinct roles in cell invasion by extracellular amastigotes of Trypanosoma cruzi. Frontiers in Microbiology, 8 (NOV) 2230, 2230. doi: 10.3389/fmicb.2017.02230
Maza, Paloma K., Bonfim-Melo, Alexis, Padovan, Ana C.B., Mortara, Renato A., Orikaza, Cristina M., Ramos, Lilian M. Damas, Moura, Tauany R., Soriani, Frederico M., Almeida, Ricardo S., Suzuki, Erika and Bahia, Diana (2017). Candida albicans: the ability to invade epithelial cells and survive under oxidative stress is unlinked to hyphal length. Frontiers in Microbiology, 8 (JUL) 1235, 1235. doi: 10.3389/fmicb.2017.01235
Garcia, Bruna G., Ooka, Tadasuke, Gotoh, Yasuhiro, Vieira, Mônica A.M., Yamamoto, Denise, Ogura, Yoshitoshi, Girão, Dennys M., Sampaio, Suely C.F., Melo, Alexis Bonfim, Irino, Kinue, Hayashi, Tetsuya and Gomes, Tânia A.T. (2016). Genetic relatedness and virulence properties of enteropathogenic Escherichia coli strains of serotype O119: H6 expressing localized adherence or localized and aggregative adherence-like patterns on HeLa cells. International Journal of Medical Microbiology, 306 (3), 152-164. doi: 10.1016/j.ijmm.2016.02.008
Ferreira, Éden Ramalho, Horjales, Eduardo, Bonfim-Melo, Alexis, Cortez, Cristian, Da Silva, Claudio Vieira, De Groote, Michel, Sobreira, Tiago José Paschoal, Cruz, Mário Costa, Lima, Fabio Mitsuo, Cordero, Esteban Mauricio, Yoshida, Nobuko, Da Silveira, José Franco, Mortara, Renato Arruda and Bahia, Diana (2016). Unique behavior of Trypanosoma cruzi mevalonate kinase: a conserved glycosomal enzyme involved in host cell invasion and signaling. Scientific Reports, 6 (1) 24610. doi: 10.1038/srep24610
Bonfim-Melo, Alexis, Zanetti, Bianca Ferrarini, Ferreira, Éden Ramalho, Vandoninck, Sandy, Han, Sang Won, Van Lint, Johan, Mortara, Renato Arruda and Bahia, Diana (2015). Trypanosoma cruzi extracellular amastigotes trigger the protein kinase D1-cortactin-actin pathway during cell invasion. Cellular Microbiology, 17 (12), 1797-1810. doi: 10.1111/cmi.12472
Florentino, P. T.V., Real, F., Bonfim-Melo, A., Orikaza, C. M., Ferreira, E. R., Pessoa, C. C., Lima, B. R., Sasso, G. R.S. and Mortara, R. A. (2014). An historical perspective on how advances in microscopic imaging contributed to understanding the Leishmania Spp. and Trypanosoma cruzi host-parasite relationship. BioMed Research International, 2014 565291, 1-16. doi: 10.1155/2014/565291
Ferreira, Éden R., Bonfim-Melo, Alexis, Mortara, Renato A. and Bahia, Diana (2012). Trypanosoma cruzi extracellular amastigotes and host cell signaling: more pieces to the puzzle. Frontiers in Immunology, 3 (NOV) Article 363. doi: 10.3389/fimmu.2012.00363
Passero, Luiz Felipe D, Carvalho, Ana Kely, Bordon, Maria Lac, Bonfim-Melo, Alexis, Carvalho, Karina, Kallás, Esper G, Santos, Bianca Ba, Toyama, Marcos H, Paes-Leme, Adriana, Corbett, Carlos Ep and Laurenti, Márcia D (2012). Proteins of Leishmania (Viannia) shawi confer protection associated with Th1 immune response and memory generation. Parasites and Vectors, 5 (1) 64. doi: 10.1186/1756-3305-5-64
Passero, Luiz Felipe Domingues, Carvalho, Ana Kely, Bordon, Maria Luiza A. C., Bonfim-Melo, Alexis, Toyama, Marcos Hikari, Corbett, Carlos Eduardo Pereira and Laurenti, Márcia Dalastra (2012). Leishmania (Viannia) shawi purified antigens confer protection against murine cutaneous leishmaniasis. Inflammation Research, 61 (3), 255-263. doi: 10.1007/s00011-011-0407-5
Zalewski, Cynthia A., Passero, Luiz Felipe D., Melo, Alexis S. R. B., Corbett, Carlos Eduardo P., Laurenti, Mãrcia D., Toyama, Marcos H., Toyama, Daniela O., Romoff, Paulete, Fávero, Oriana A. and Lago, João Henrique G. (2011). Evaluation of anti-inflammatory activity of derivatives from aerial parts of Baccharis uncinella. Pharmaceutical Biology, 49 (6), 602-607. doi: 10.3109/13880209.2010.537828
Passero, Luiz Felipe D., Bonfim-Melo, Alexis, Corbett, Carlos Eduardo P., Laurenti, Márcia D., Toyama, Marcos H., De Toyama, Daniela O., Romoff, Paulete, Fávero, Oriana A., Dos Grecco, Simone S., Zalewsky, Cynthia A. and Lago, João Henrique G. (2011). Anti-leishmanial effects of purified compounds from aerial parts of Baccharis uncinella C. DC. (Asteraceae). Parasitology Research, 108 (3), 529-536. doi: 10.1007/s00436-010-2091-8