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2018 dates

  • 9-13 April (Commonwealth Games week) - Years 10, 11 and 12 only
  • 2-6 July - Years 10, 11, 12 - Residential regional and remote student Immersion (min age 15 years) - accommodation UQ College
  • 9-13 July UQ special event - Years 10, 11, and 12 - Residential regional student Immersion (min age 15 years) - accommodation UQ College
  • 17-21 September (Last week of term 3) - Years 10, 11, and 12
  • 24-28 September - Years 10, 11, and 12
  • 2-5 October - Years 10, 11, and 12
  • 3-7 December - Years 10 and 11 only
  • 10-14 December - Years 10 and 11 only

9-13 April - Investigation of Retrotransposon Activity by Flow Cytometry

Mobile DNA or RNA elements (i.e. transposons/ retrotransposons or “jumping genes”) are believed to be critical drivers of evolution. These are repetitive nucleotide sequences that can cut or copy themselves out of the genome and re-insert elsewhere in the genome. Depending on their re-insertion site, transposons and retrotransposons can disrupt critical genes and inactivate them or alter their expression so as to cause disease. Mobilisation of transposons has been widely studied in many disease states including cancer, and up to 18 human diseases have been identified to be caused by recent insertion events.  

In this immersion program, we will measure the rate of retrotransposon activity in cells using reporter assays based on green and cherry fluorescent proteins and antibiotic resistance. The assays will reveal the role of key enzymes involved in the retrotransposition process. Students will be immersed in conducting modern-day research techniques including cell culture, transfection of mammalian cells with DNA, followed by techniques to measure reporter-gene activity including flow cytometric and microscopy-based analyses.

Learn more about Flow Cytometry.

Flow cytometry